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The map label for this gene is alr

Identifier: 78224104

GI number: 78224104

Start: 3291515

End: 3292654

Strand: Reverse

Name: alr

Synonym: Gmet_2908

Alternate gene names: 78224104

Gene position: 3292654-3291515 (Counterclockwise)

Preceding gene: 78224107

Following gene: 78224103

Centisome position: 82.37

GC content: 66.49

Gene sequence:

>1140_bases
ATGGACAGTCGCCCCACCATTGCCGAAATCGATCTTGCCGCCCTGCGTCATAACTTCGAGCAGGTGCAGCGTGCCGTTCC
CGCCGGATGCGGGATTCTTGCCATCGTGAAGGCCGATGCCTACGGCCACGGCTTCATGGATATCTCCCGGGAACTGGAGT
CCCTGGGGGTGACCGCCTTCGGCGTGGCGTTTCTGGCCGAGGGAATCCAACTGCGCAAGAGCGGCATCGACCGGCCGGTC
CTGATCCTCGGCGGGGTCTATCCGGGGCAGGAGCGCAAGTGCGTCGGGTTCAACCTCTCCACCGCCGTCTTCTCCCTGGA
GCAGGCGCGGGTCCTGAACGACACCGCCGCCCGTCTCTACCGCAAGGCGAAGATCCACGTGAAGATCGATACCGGCATGG
GGCGTCTCGGGGTCGCCGCGGCCGAGGCCCCGGCCTTTTTCCGGGAACTGCGGGAGATGAAATCCCTGGAACTGGAGGGG
ATCATCTCTCACTTCGCCTCCGCCGACGAACTGGATGATGATGGCCGCCGCTTCTCGGACCGCCAGGCTGCCGTCTTCGC
CCAGTCGGTGGCAGAGGCCCGGTCCCTGGGACTCGACCCCCGCTACGTCCACATCGCCAACAGTGCCGCCGCTTTCGGCA
TGGATCTCCCCTTCTGCAACCTGGTCCGGCCCGGCATCGTCCTCTACGGGGCGCTTCCGTCGGGTGACTTCGAGGGAAAG
ATGGCGCTCCGGCCCATCATGCGGCTGCAGAGTACCGTGGCCATGCTCAAGTGGGTGGAGCCCGGCACCAGTATCAGCTA
CGCCCGCCGCTACACGGCCCCGGACCGGCGCCTTATCGCCAGTGTTCCCGTGGGGTACGCCGACGGCTACAGCCGGGCCC
TGACCAACCGGGGAGAGGTCCTGATCCGGGGCACGCGGGCACCGGTGGTTGGGACCGTCTGCATGGACTGGATCATGATC
GATGTGACCTCCGTCCCTGGCGTGGCTGTGGGGGACGAGGTGACGCTCCTTGGCTGCGACCGGCAGGGTCATTGCGTGCG
GGCCGAGGAACTGGCCTCGTGGGCCGGCACCATCCCCTACGAAATTTTCTGCGGCATCAGCAAGCGGGTGCCGCGGGTCT
ACCTGAACGCGACCCGGTGA

Upstream 100 bases:

>100_bases
TTAACCCGTTGACGCCGGGCGGATTTCACCCTGAAGCGGGGGCATCACAGTGTCAGGTTCATGCTTTACACCACCGGCGG
GAAGTGGTAGGAAAAGGGGC

Downstream 100 bases:

>100_bases
CTGTGATGATCAAGCTGACATCCCTCGTAAAAGCGGCCGGCTGAGCGGCCAAGCTGGGCCCGGCGGGCCTGGAAGACGCA
CTGAGCGGCATCCTGGGGAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAFGVAFLAEGIQLRKSGIDRPV
LILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLYRKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEG
IISHFASADELDDDGRRFSDRQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGK
MALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEVLIRGTRAPVVGTVCMDWIMI
DVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPYEIFCGISKRVPRVYLNATR

Sequences:

>Translated_379_residues
MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAFGVAFLAEGIQLRKSGIDRPV
LILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLYRKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEG
IISHFASADELDDDGRRFSDRQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGK
MALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEVLIRGTRAPVVGTVCMDWIMI
DVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPYEIFCGISKRVPRVYLNATR
>Mature_379_residues
MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAFGVAFLAEGIQLRKSGIDRPV
LILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLYRKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEG
IISHFASADELDDDGRRFSDRQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGK
MALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEVLIRGTRAPVVGTVCMDWIMI
DVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPYEIFCGISKRVPRVYLNATR

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=375, Percent_Identity=34.9333333333333, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=32.3450134770889, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_GEOMG (Q39RJ8)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385851.1
- HSSP:   P10724
- ProteinModelPortal:   Q39RJ8
- SMR:   Q39RJ8
- STRING:   Q39RJ8
- GeneID:   3740858
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2908
- NMPDR:   fig|269799.3.peg.3140
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   TEDESII
- PhylomeDB:   Q39RJ8
- ProtClustDB:   CLSK827943
- BioCyc:   GMET269799:GMET_2908-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 41180; Mature: 41180

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 37-37 ACT_SITE 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHH
GVAFLAEGIQLRKSGIDRPVLILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLY
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
RKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEGIISHFASADELDDDGRRFSD
HEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
RQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGK
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCHHHHCCCCEEEEECCCCCCCCCC
MALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHCCCCCE
LIRGTRAPVVGTVCMDWIMIDVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPY
EEEECCCCCHHHHHHHHHEEEEECCCCEEECCCEEEEECCCCCCEECHHHHHHHCCCCCH
EIFCGISKRVPRVYLNATR
HEEECCHHCCCEEEEEECC
>Mature Secondary Structure
MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHH
GVAFLAEGIQLRKSGIDRPVLILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLY
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
RKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEGIISHFASADELDDDGRRFSD
HEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
RQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGK
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCHHHHCCCCEEEEECCCCCCCCCC
MALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHCCCCCE
LIRGTRAPVVGTVCMDWIMIDVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPY
EEEECCCCCHHHHHHHHHEEEEECCCCEEECCCEEEEECCCCCCEECHHHHHHHCCCCCH
EIFCGISKRVPRVYLNATR
HEEECCHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA