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The map label for this gene is 78224011

Identifier: 78224011

GI number: 78224011

Start: 3181621

End: 3182796

Strand: Reverse

Name: 78224011

Synonym: Gmet_2815

Alternate gene names: NA

Gene position: 3182796-3181621 (Counterclockwise)

Preceding gene: 78224014

Following gene: 78224010

Centisome position: 79.62

GC content: 66.41

Gene sequence:

>1176_bases
ATGCTCACCACGGTGCTCCCGTTTCTCTGCATCCTCCCTCCCCTTGCCTACGGCGTTATCGCCCTCGGTTGCGCCCGGTC
CTACTTTGGCCGCCGGCGCCCCGCGCCGGGGCACACGCCCCCCATTTCGATCCTCAAGCCGGTAAAGGGGATGGACGCCG
GGAGCTTTGACAACTTCGCCTCCTTCTGTCGCCAGGAGTATCCTGCCCCGTGGCAGATCGTCTTTGCCGTCGCTGACCCC
GCCGACCCGGTGATTCCCGTCATCGGGCGGCTCATGGGGGAGTTTCCCGCCATCGACATGGAGCTGGTGGTGGACGCCAC
CATCCACGGCCCGAACCACAAGGTCTCGAACCTGATCAACGCCTGCCCCAAGGCAAAGCACGATCTCCTCATCGTCTGCG
ACAGCGACATCCGGGTCTCCCCCGACTACCTCCGGGAGGTGGCGGCCCCCTTCGCCGACCAACAGGTGGGGCTCGTCACC
TCCCTCTACCGCAGCCCCGGCGTGGCGGGCGCCGCCACGGCCGTGGAGGCCATGGGATTCACGGTGGAGATGATTCCCAA
CGTCATGGTGGCCATGAAGCTGGAGGGGCTCTCCTTTGCCCTGGGGGCCTCCATGGCGGTGCGCCGGGAGGCTCTGGAGG
CAATCGGCGGCTTTGCCGCCCTGGCCGATTACCTGGCCGACGACTACCAGCTCGGCAACAAGGTCCACAAGGTGGGGTGG
CGGCTGGAACTCTCCGACTGCTTCGTGGAGAGCGTCATGCACCGGGAGGATCTGGCCACGGTCCTCTCCCGCCAGCTCCG
CTGGTCGCGCACCATGCGGGTCTCGCGCCCCGGCGGCTACCTCGGCTCCGGCATCACCCAGTCATTTCCCATGGCCTGTC
TGGCGCTGGCCCTTTCCGGATTTTCCGGCGCCGGCTGGGGGGCCGTCCTCCTCCTCTACCTAGTCCGCGCCGCCGTGGCC
ATGGCCTTCAGCCGCTGTTACGTGAAGGACGGCATTTTTCCCCGCTGGCTCTGGCTCCTTCCCCTGCGGGACTTCCTCGC
CTTCGCCACCTGGGCCCTCTCCTTCGCGGGAAACCGCGTCCGCTGGCGGGGAAACCTGTTCCGGCTTCTTCCCGGCGGCA
AGATCGTTGAATTGCCAAAAACATTTGAAACACGGGGCAACGGAGCAACGGAGTAA

Upstream 100 bases:

>100_bases
CGCAAGAGGCAAACCCCGGTCTGGACGAGTTTTGCGTTGCAATGGCTCCGCGAACAGGGGTAAATAGGCGCAAGAACAAT
CCCGCGAGGTTTTCGGCATT

Downstream 100 bases:

>100_bases
AATCTGTGGGGAAAATGCTCTCAGGCCCGTGTAGGAACCAACTTCCGGCTCATCCCCTGTCCATCGCGAAACTGCGCCGG
CGCCGGCGACCTTTCCCGTG

Product: ceramide glucosyltransferase

Products: UDP; D-glucosyl-N-acylsphingosine

Alternate protein names: Glycosyltransferase; Glycosyl Transferase Family Protein; Glucosyltransferase; Cell Wall Biosynthesis Glycosyltransferase-Like Protein; Glycosyl Transferase Group 2 Family; Glycosyl Transferase; Cell Wall Biosynthesis Glycosyltransferase; Glycosyl Transferase Group 2 Family Protein; Acyl-CoA Dehydrogenase-Like; Acyl-CoA Dehydrogenase-Like Protein; UDP-GlucoseCeramide Glycosyltransferase; Glycosyl Transferase Protein; Glycosyl Tranferase Homolog; Syl Transferase Group 2 Family Protein; Putatiave Glycosyltransferase; Family 2 Glycosyl Transferase

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLTTVLPFLCILPPLAYGVIALGCARSYFGRRRPAPGHTPPISILKPVKGMDAGSFDNFASFCRQEYPAPWQIVFAVADP
ADPVIPVIGRLMGEFPAIDMELVVDATIHGPNHKVSNLINACPKAKHDLLIVCDSDIRVSPDYLREVAAPFADQQVGLVT
SLYRSPGVAGAATAVEAMGFTVEMIPNVMVAMKLEGLSFALGASMAVRREALEAIGGFAALADYLADDYQLGNKVHKVGW
RLELSDCFVESVMHREDLATVLSRQLRWSRTMRVSRPGGYLGSGITQSFPMACLALALSGFSGAGWGAVLLLYLVRAAVA
MAFSRCYVKDGIFPRWLWLLPLRDFLAFATWALSFAGNRVRWRGNLFRLLPGGKIVELPKTFETRGNGATE

Sequences:

>Translated_391_residues
MLTTVLPFLCILPPLAYGVIALGCARSYFGRRRPAPGHTPPISILKPVKGMDAGSFDNFASFCRQEYPAPWQIVFAVADP
ADPVIPVIGRLMGEFPAIDMELVVDATIHGPNHKVSNLINACPKAKHDLLIVCDSDIRVSPDYLREVAAPFADQQVGLVT
SLYRSPGVAGAATAVEAMGFTVEMIPNVMVAMKLEGLSFALGASMAVRREALEAIGGFAALADYLADDYQLGNKVHKVGW
RLELSDCFVESVMHREDLATVLSRQLRWSRTMRVSRPGGYLGSGITQSFPMACLALALSGFSGAGWGAVLLLYLVRAAVA
MAFSRCYVKDGIFPRWLWLLPLRDFLAFATWALSFAGNRVRWRGNLFRLLPGGKIVELPKTFETRGNGATE
>Mature_391_residues
MLTTVLPFLCILPPLAYGVIALGCARSYFGRRRPAPGHTPPISILKPVKGMDAGSFDNFASFCRQEYPAPWQIVFAVADP
ADPVIPVIGRLMGEFPAIDMELVVDATIHGPNHKVSNLINACPKAKHDLLIVCDSDIRVSPDYLREVAAPFADQQVGLVT
SLYRSPGVAGAATAVEAMGFTVEMIPNVMVAMKLEGLSFALGASMAVRREALEAIGGFAALADYLADDYQLGNKVHKVGW
RLELSDCFVESVMHREDLATVLSRQLRWSRTMRVSRPGGYLGSGITQSFPMACLALALSGFSGAGWGAVLLLYLVRAAVA
MAFSRCYVKDGIFPRWLWLLPLRDFLAFATWALSFAGNRVRWRGNLFRLLPGGKIVELPKTFETRGNGATE

Specific function: Unknown

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4507811, Length=350, Percent_Identity=25.7142857142857, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25147526, Length=349, Percent_Identity=24.3553008595989, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32564728, Length=382, Percent_Identity=23.0366492146597, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25149574, Length=382, Percent_Identity=23.0366492146597, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25149577, Length=382, Percent_Identity=23.0366492146597, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25149580, Length=270, Percent_Identity=24.0740740740741, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566973, Length=383, Percent_Identity=24.2819843342037, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24657569, Length=365, Percent_Identity=24.3835616438356, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.80

Molecular weight: Translated: 42567; Mature: 42567

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTVLPFLCILPPLAYGVIALGCARSYFGRRRPAPGHTPPISILKPVKGMDAGSFDNFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHH
SFCRQEYPAPWQIVFAVADPADPVIPVIGRLMGEFPAIDMELVVDATIHGPNHKVSNLIN
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHH
ACPKAKHDLLIVCDSDIRVSPDYLREVAAPFADQQVGLVTSLYRSPGVAGAATAVEAMGF
HCCCCCCCEEEEECCCCEECHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCC
TVEMIPNVMVAMKLEGLSFALGASMAVRREALEAIGGFAALADYLADDYQLGNKVHKVGW
HHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
RLELSDCFVESVMHREDLATVLSRQLRWSRTMRVSRPGGYLGSGITQSFPMACLALALSG
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHC
FSGAGWGAVLLLYLVRAAVAMAFSRCYVKDGIFPRWLWLLPLRDFLAFATWALSFAGNRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
RWRGNLFRLLPGGKIVELPKTFETRGNGATE
EEECCEEEECCCCCEEECCCHHHCCCCCCCC
>Mature Secondary Structure
MLTTVLPFLCILPPLAYGVIALGCARSYFGRRRPAPGHTPPISILKPVKGMDAGSFDNFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHH
SFCRQEYPAPWQIVFAVADPADPVIPVIGRLMGEFPAIDMELVVDATIHGPNHKVSNLIN
HHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHH
ACPKAKHDLLIVCDSDIRVSPDYLREVAAPFADQQVGLVTSLYRSPGVAGAATAVEAMGF
HCCCCCCCEEEEECCCCEECHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCC
TVEMIPNVMVAMKLEGLSFALGASMAVRREALEAIGGFAALADYLADDYQLGNKVHKVGW
HHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
RLELSDCFVESVMHREDLATVLSRQLRWSRTMRVSRPGGYLGSGITQSFPMACLALALSG
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHC
FSGAGWGAVLLLYLVRAAVAMAFSRCYVKDGIFPRWLWLLPLRDFLAFATWALSFAGNRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
RWRGNLFRLLPGGKIVELPKTFETRGNGATE
EEECCEEEECCCCCEEECCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; N-acylsphingosine

Specific reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA