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The map label for this gene is lpxH [H]

Identifier: 78223972

GI number: 78223972

Start: 3140688

End: 3141428

Strand: Direct

Name: lpxH [H]

Synonym: Gmet_2776

Alternate gene names: 78223972

Gene position: 3140688-3141428 (Clockwise)

Preceding gene: 78223939

Following gene: 78223978

Centisome position: 78.57

GC content: 63.83

Gene sequence:

>741_bases
ATGCGCGCTATCTTCATCGCCGATGCCCATCTGCGGCACGAGGGGGACGAAAACTACCGGCTCCTCGTGGAATTTCTTAC
AGAACTCCGGGGAACCGTCGACACGCTCTTCATCCTCGGCGATCTCTTCGAATTCTGGATCGGCTACGAAACGGTCCCCT
TCACCCACTACCTTCCGATTCTGAAAAAGCTCCAGGAGCTGGCGGAAAATGGCACGGAAATCGTCTACCTGGAGGGAAAC
CACGACTTCCACATGGGGCCGTTCTTCACCAAGACCCTCGGCGCCCGGGTCCATCCCGGCCCGGCCCTCGTCACCATCGA
GGGGAAACAGGTCTATCTCTGCCACGGCGACGAGGTGAACAGCCGGGATTACTCCTACCGGCTCCTCCGCTTCATCCTCC
ACAGCTCCCTCGTCCGGGCGGCCACCCGTGTCGTTCCCCCCTCGGTCGCCTCCCGTATCGCCGAGCGGATGTCCCGCGGC
AGCAGGAAGAACCATGGCCGGCGGCAGCACCGCTGGGATTACCCGGCGCTCCTGCGGGAATTCGCCGCCCGGCGCTTCCG
CGAGGGGTGCGACGTGGTTGTCTCGGGCCACTTCCACATCCCGTTCCTGGACGAAGCCGACGGAAAGGTTCTCCTCTCCC
TGGGTGACTGGCTCACCCACTATACCTACGGGGAGTGGCGGGACGGGGTGGTATCGCTGAGGCGATACCGGTACCGGGGA
CCGGGGACCGGGGACCAGTAA

Upstream 100 bases:

>100_bases
TCGTCCCAGACTATCTCCACATCACGCATGAACCCCATGGCTAACCCGTCTTCCTCTCTCTATCTTTACCTTTGCAGGCC
TTTTGTTCTATAGTGCCGCC

Downstream 100 bases:

>100_bases
AAACCTTCACGTCACGTCGAGGCCGAAGAGCCTCAGATATTTCCCAACCCGCTCCTCCAGGGTCGGCGCCGCCACCAGGA
GGCAGGTTTCGTCGGGGCGA

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRAIFIADAHLRHEGDENYRLLVEFLTELRGTVDTLFILGDLFEFWIGYETVPFTHYLPILKKLQELAENGTEIVYLEGN
HDFHMGPFFTKTLGARVHPGPALVTIEGKQVYLCHGDEVNSRDYSYRLLRFILHSSLVRAATRVVPPSVASRIAERMSRG
SRKNHGRRQHRWDYPALLREFAARRFREGCDVVVSGHFHIPFLDEADGKVLLSLGDWLTHYTYGEWRDGVVSLRRYRYRG
PGTGDQ

Sequences:

>Translated_246_residues
MRAIFIADAHLRHEGDENYRLLVEFLTELRGTVDTLFILGDLFEFWIGYETVPFTHYLPILKKLQELAENGTEIVYLEGN
HDFHMGPFFTKTLGARVHPGPALVTIEGKQVYLCHGDEVNSRDYSYRLLRFILHSSLVRAATRVVPPSVASRIAERMSRG
SRKNHGRRQHRWDYPALLREFAARRFREGCDVVVSGHFHIPFLDEADGKVLLSLGDWLTHYTYGEWRDGVVSLRRYRYRG
PGTGDQ
>Mature_246_residues
MRAIFIADAHLRHEGDENYRLLVEFLTELRGTVDTLFILGDLFEFWIGYETVPFTHYLPILKKLQELAENGTEIVYLEGN
HDFHMGPFFTKTLGARVHPGPALVTIEGKQVYLCHGDEVNSRDYSYRLLRFILHSSLVRAATRVVPPSVASRIAERMSRG
SRKNHGRRQHRWDYPALLREFAARRFREGCDVVVSGHFHIPFLDEADGKVLLSLGDWLTHYTYGEWRDGVVSLRRYRYRG
PGTGDQ

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=169, Percent_Identity=28.9940828402367, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 28462; Mature: 28462

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIFIADAHLRHEGDENYRLLVEFLTELRGTVDTLFILGDLFEFWIGYETVPFTHYLPI
CCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LKKLQELAENGTEIVYLEGNHDFHMGPFFTKTLGARVHPGPALVTIEGKQVYLCHGDEVN
HHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCEECCCCEEEEEECCEEEEEECCCCC
SRDYSYRLLRFILHSSLVRAATRVVPPSVASRIAERMSRGSRKNHGRRQHRWDYPALLRE
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHH
FAARRFREGCDVVVSGHFHIPFLDEADGKVLLSLGDWLTHYTYGEWRDGVVSLRRYRYRG
HHHHHHHCCCCEEEECCEECCEEECCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHCCC
PGTGDQ
CCCCCC
>Mature Secondary Structure
MRAIFIADAHLRHEGDENYRLLVEFLTELRGTVDTLFILGDLFEFWIGYETVPFTHYLPI
CCEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LKKLQELAENGTEIVYLEGNHDFHMGPFFTKTLGARVHPGPALVTIEGKQVYLCHGDEVN
HHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCEECCCCEEEEEECCEEEEEECCCCC
SRDYSYRLLRFILHSSLVRAATRVVPPSVASRIAERMSRGSRKNHGRRQHRWDYPALLRE
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHH
FAARRFREGCDVVVSGHFHIPFLDEADGKVLLSLGDWLTHYTYGEWRDGVVSLRRYRYRG
HHHHHHHCCCCEEEECCEECCEEECCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHCCC
PGTGDQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA