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The map label for this gene is lytT [H]

Identifier: 78223893

GI number: 78223893

Start: 3046200

End: 3046922

Strand: Reverse

Name: lytT [H]

Synonym: Gmet_2697

Alternate gene names: 78223893

Gene position: 3046922-3046200 (Counterclockwise)

Preceding gene: 78223894

Following gene: 78223892

Centisome position: 76.22

GC content: 64.18

Gene sequence:

>723_bases
ATGAGAGTCTTCATCGTTGACGACGAGGCACCGGCTCGGCGGGAGCTCAGGTACCTTCTGGAGCGCGTGGAGGGGGTGGA
GGTTGCCGGCGAGGCCGCCAACGGCACCGAGGCCCTCAAGGGGATCAGGCAGACCCGCCCCCAGCTGGTGTTCCTTGACA
TCCAGATGCCGGGCCTGTCGGGGTTGGAGCTGGCCCAGTTCCTGGCCGAACTTCCCACAAGACCGTTGCTGGTCTTCGCC
ACGGCGTTCCAGGAGTATGCCCTCCAGGCCTTCGAGGTGGAGGCCTTCGACTACCTGCTCAAGCCCTTCGACAAGGAGCG
CCTGGAGAAGACGGTGATGAAGGCCGCCCGGGCGCTCGCTCCCCCAGCGGGGCGGGAACCCGGCGAACCCGGCAGGAAGA
TAGCGCTCTATCGGGGCGAGACTATCATCCCCACCGCACCGGAGCGGATCCTGTTCGCCCGGAGCGAGGGGGGGGAGGTC
GTCGTCCATGCCGGCGACGGGCGGTACCGTACCCGCTTCACCCTCAACGAACTAGAGCAGAAGCTCTCCCCCTCGGGCTT
CGTCCGGGTCCACCGGAGTTTCCTGGTCAACACGAACCATGTCCGGGAGGTCGTGCCGTGGTTCCACGGCAGCTACAAAC
TGATCATGGACGACCGGGAGAAGTCCGAAATCCCCGTCAGCCGGTACAACGTGAAAGATCTAAAAAGGTATTTCGATATC
TGA

Upstream 100 bases:

>100_bases
CTGTACGGGCCGGAGCATGCCCTGCGGGTGGAAAGCACCCCGGGAGCGGGGACCACCGTGTCATTCACGGTGCCCCAAGG
GGGGAGGGGGGAGTATGCTC

Downstream 100 bases:

>100_bases
GCCCCCATTCGTCTCCCCGCGGCAACCATTCATCCCCCGATTACGACCATTCACCGTTTTTCCGGTTTTTCCCCGCGCGT
TTCCTCTATGCTGAACCATA

Product: LytR/AlgR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRVFIVDDEAPARRELRYLLERVEGVEVAGEAANGTEALKGIRQTRPQLVFLDIQMPGLSGLELAQFLAELPTRPLLVFA
TAFQEYALQAFEVEAFDYLLKPFDKERLEKTVMKAARALAPPAGREPGEPGRKIALYRGETIIPTAPERILFARSEGGEV
VVHAGDGRYRTRFTLNELEQKLSPSGFVRVHRSFLVNTNHVREVVPWFHGSYKLIMDDREKSEIPVSRYNVKDLKRYFDI

Sequences:

>Translated_240_residues
MRVFIVDDEAPARRELRYLLERVEGVEVAGEAANGTEALKGIRQTRPQLVFLDIQMPGLSGLELAQFLAELPTRPLLVFA
TAFQEYALQAFEVEAFDYLLKPFDKERLEKTVMKAARALAPPAGREPGEPGRKIALYRGETIIPTAPERILFARSEGGEV
VVHAGDGRYRTRFTLNELEQKLSPSGFVRVHRSFLVNTNHVREVVPWFHGSYKLIMDDREKSEIPVSRYNVKDLKRYFDI
>Mature_240_residues
MRVFIVDDEAPARRELRYLLERVEGVEVAGEAANGTEALKGIRQTRPQLVFLDIQMPGLSGLELAQFLAELPTRPLLVFA
TAFQEYALQAFEVEAFDYLLKPFDKERLEKTVMKAARALAPPAGREPGEPGRKIALYRGETIIPTAPERILFARSEGGEV
VVHAGDGRYRTRFTLNELEQKLSPSGFVRVHRSFLVNTNHVREVVPWFHGSYKLIMDDREKSEIPVSRYNVKDLKRYFDI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=242, Percent_Identity=36.7768595041322, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87082052, Length=240, Percent_Identity=37.5, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27346; Mature: 27346

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFIVDDEAPARRELRYLLERVEGVEVAGEAANGTEALKGIRQTRPQLVFLDIQMPGLS
CEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
GLELAQFLAELPTRPLLVFATAFQEYALQAFEVEAFDYLLKPFDKERLEKTVMKAARALA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PPAGREPGEPGRKIALYRGETIIPTAPERILFARSEGGEVVVHAGDGRYRTRFTLNELEQ
CCCCCCCCCCCCEEEEEECCEECCCCCCCEEEEECCCCEEEEECCCCCEEEEEEHHHHHH
KLSPSGFVRVHRSFLVNTNHVREVVPWFHGSYKLIMDDREKSEIPVSRYNVKDLKRYFDI
HCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCHHHHHHHHCC
>Mature Secondary Structure
MRVFIVDDEAPARRELRYLLERVEGVEVAGEAANGTEALKGIRQTRPQLVFLDIQMPGLS
CEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCC
GLELAQFLAELPTRPLLVFATAFQEYALQAFEVEAFDYLLKPFDKERLEKTVMKAARALA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
PPAGREPGEPGRKIALYRGETIIPTAPERILFARSEGGEVVVHAGDGRYRTRFTLNELEQ
CCCCCCCCCCCCEEEEEECCEECCCCCCCEEEEECCCCEEEEECCCCCEEEEEEHHHHHH
KLSPSGFVRVHRSFLVNTNHVREVVPWFHGSYKLIMDDREKSEIPVSRYNVKDLKRYFDI
HCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]