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The map label for this gene is trpB [H]

Identifier: 78223685

GI number: 78223685

Start: 2824488

End: 2825678

Strand: Reverse

Name: trpB [H]

Synonym: Gmet_2482

Alternate gene names: 78223685

Gene position: 2825678-2824488 (Counterclockwise)

Preceding gene: 78223686

Following gene: 78223684

Centisome position: 70.69

GC content: 65.07

Gene sequence:

>1191_bases
ATGAAATTACCCGACAAACAGGGCCACTTCGGCCAGTTCGGCGGCCGTTACGTGCCGGAAACCCTCATGCCGGCGCTCCT
GGAGCTGGAGAAGGCCTACAACCACTACAAGAACGACCGCGAGTTCAAGGAGGAGTTCGACTACTACCTCCGCCAGTACG
TGGGGCGCCCCAATCCCCTCTACTTTGCCGAGAAGCTCACGCAAAAGCTGGGGGGCGCGAAGATCTACCTCAAGCGCGAG
GACCTGAACCACACCGGTGCCCACAAGGTGAACAATACCATCGGCCAGGGGCTTCTGGCCAAGCGGATGGGGAAGAAACG
GGTCATTGCCGAGACCGGTGCCGGCCAGCACGGGGTGGCCACGGCCACCATTGCGGCCCTCTTCGGCATGGAGTGCGAGG
TCTTCATGGGGGAGGAGGATATCCGGCGCCAGGCCCTGAACGTCTTCCGGATGAAGCTCCTGGGGGCGAAGGTTACGCCG
GTGACCGCCGGCACCGCCACCCTCAAGGACGCCATGAACGAGGCCATGCGGAACTGGGTGACCTACATCCACAACACCTT
CTACGTGATCGGCACCGTGGCGGGACCCCACCCCTATCCGGTGATGGTCCGCGACTTCCAGTCGGTCATCGGCCGGGAGG
CCAAGGCCCAGCACAAGAAGATCGAGGGAAGGTTGCCGGATGTTCTCGTTGCCTGCGTCGGCGGCGGCAGCAATGCCCTG
GGGCTCTTCTACCCGTTCCTCAATGACCGGGAGGTCCGGATGGTGGGGGTGGAGGCCGCGGGCCACGGCATCGCCTCCGG
AGCCCACGCGGCGCCGCTCTGCGCCGGGACGGTCGGCGTTCTCCACGGCAACAAGACCTACCTCCTCCAGGATGAGTTCG
GCCAGATAGCCAATGCCCACTCCGTTTCCGCCGGCCTTGATTACCCCGGCGTTGGCCCCGAGCACGCCTGGCTCAAGGAT
TCCAGGCGGGCCGAGTATGTGTCGGTCACCGACGATGAGGCCCTGGAGGCCTTCACGCTCCTGACCCGGGAGGAGGGGAT
CATGCCGGCCCTGGAGTCGTCCCACGCCATCGCCCACGTGGTGAAGCTGGCGCCGACACTGCCGAGGGAGCAGACCATCG
TCGCCTGCCTCTCCGGCCGGGGGGACAAGGATATTCACACGGTGGCCGACGCCATGGGGGTACAGTTTTAG

Upstream 100 bases:

>100_bases
TCTTGATGTGGCTCCTCCTGATGTGTGACAATATATGGCCCGCAGTTTCCCGATATCAGCCGGTGCGACTGATTTCTAAT
ACTACCGATGGAGGATATCC

Downstream 100 bases:

>100_bases
TATTTGTAAAAATGAACACTATGCCGAAAAATGCCTTTGTAACTTGTTGAAAATACAGGCTAATATAAAAAAATAGCTTG
ACATTGCACGCTGTTTTACC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKLPDKQGHFGQFGGRYVPETLMPALLELEKAYNHYKNDREFKEEFDYYLRQYVGRPNPLYFAEKLTQKLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVATATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGAKVTP
VTAGTATLKDAMNEAMRNWVTYIHNTFYVIGTVAGPHPYPVMVRDFQSVIGREAKAQHKKIEGRLPDVLVACVGGGSNAL
GLFYPFLNDREVRMVGVEAAGHGIASGAHAAPLCAGTVGVLHGNKTYLLQDEFGQIANAHSVSAGLDYPGVGPEHAWLKD
SRRAEYVSVTDDEALEAFTLLTREEGIMPALESSHAIAHVVKLAPTLPREQTIVACLSGRGDKDIHTVADAMGVQF

Sequences:

>Translated_396_residues
MKLPDKQGHFGQFGGRYVPETLMPALLELEKAYNHYKNDREFKEEFDYYLRQYVGRPNPLYFAEKLTQKLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVATATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGAKVTP
VTAGTATLKDAMNEAMRNWVTYIHNTFYVIGTVAGPHPYPVMVRDFQSVIGREAKAQHKKIEGRLPDVLVACVGGGSNAL
GLFYPFLNDREVRMVGVEAAGHGIASGAHAAPLCAGTVGVLHGNKTYLLQDEFGQIANAHSVSAGLDYPGVGPEHAWLKD
SRRAEYVSVTDDEALEAFTLLTREEGIMPALESSHAIAHVVKLAPTLPREQTIVACLSGRGDKDIHTVADAMGVQF
>Mature_396_residues
MKLPDKQGHFGQFGGRYVPETLMPALLELEKAYNHYKNDREFKEEFDYYLRQYVGRPNPLYFAEKLTQKLGGAKIYLKRE
DLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVATATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGAKVTP
VTAGTATLKDAMNEAMRNWVTYIHNTFYVIGTVAGPHPYPVMVRDFQSVIGREAKAQHKKIEGRLPDVLVACVGGGSNAL
GLFYPFLNDREVRMVGVEAAGHGIASGAHAAPLCAGTVGVLHGNKTYLLQDEFGQIANAHSVSAGLDYPGVGPEHAWLKD
SRRAEYVSVTDDEALEAFTLLTREEGIMPALESSHAIAHVVKLAPTLPREQTIVACLSGRGDKDIHTVADAMGVQF

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=55.8441558441558, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=58.3333333333333, Blast_Score=459, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43317; Mature: 43317

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPDKQGHFGQFGGRYVPETLMPALLELEKAYNHYKNDREFKEEFDYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTQKLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
TATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGAKVTPVTAGTATLKDAMNEAMRNWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TYIHNTFYVIGTVAGPHPYPVMVRDFQSVIGREAKAQHKKIEGRLPDVLVACVGGGSNAL
HHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCE
GLFYPFLNDREVRMVGVEAAGHGIASGAHAAPLCAGTVGVLHGNKTYLLQDEFGQIANAH
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCEEEEECCEEEEECHHHHHHHCCC
SVSAGLDYPGVGPEHAWLKDSRRAEYVSVTDDEALEAFTLLTREEGIMPALESSHAIAHV
CCCCCCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
VKLAPTLPREQTIVACLSGRGDKDIHTVADAMGVQF
HHHCCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKLPDKQGHFGQFGGRYVPETLMPALLELEKAYNHYKNDREFKEEFDYYLRQYVGRPNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCH
YFAEKLTQKLGGAKIYLKREDLNHTGAHKVNNTIGQGLLAKRMGKKRVIAETGAGQHGVA
HHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
TATIAALFGMECEVFMGEEDIRRQALNVFRMKLLGAKVTPVTAGTATLKDAMNEAMRNWV
HHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
TYIHNTFYVIGTVAGPHPYPVMVRDFQSVIGREAKAQHKKIEGRLPDVLVACVGGGSNAL
HHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCE
GLFYPFLNDREVRMVGVEAAGHGIASGAHAAPLCAGTVGVLHGNKTYLLQDEFGQIANAH
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCEEEEECCEEEEECHHHHHHHCCC
SVSAGLDYPGVGPEHAWLKDSRRAEYVSVTDDEALEAFTLLTREEGIMPALESSHAIAHV
CCCCCCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHCCHHHHHH
VKLAPTLPREQTIVACLSGRGDKDIHTVADAMGVQF
HHHCCCCCCHHHEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA