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The map label for this gene is lnt

Identifier: 78223570

GI number: 78223570

Start: 2674828

End: 2676393

Strand: Reverse

Name: lnt

Synonym: Gmet_2367

Alternate gene names: 78223570

Gene position: 2676393-2674828 (Counterclockwise)

Preceding gene: 78223571

Following gene: 78223569

Centisome position: 66.95

GC content: 63.22

Gene sequence:

>1566_bases
GTGGACTACCGCAGATTACGGATGCCCGATTTTGACGCCATTCCACGGCGTGACTACCTGATGGCGGTTCTCTCGGGGGT
GCTCCTTGCCCTCTCGTTCCCGAGTCCCGGCATCTCCCCCCTGGCCTGGATCGCGTTTGCGCCGCTCCTGCTCGCCTGCG
GCCGGAAGGACCCCCGCAAGGCCTTCCGGCTGGGGTTCGTCACAGGACTCGCCGCCTACGCCGGGATTCTCTACTGGATC
ACCATTGTCGTCACCACCTACGGAAAGCTTCCGTGGATCGTGAGCGTCGGCGTCCTTTCCATGCTCGTGTCCTACCTGGC
CCTCTATCCGGCCGTGGTGGCCTATCTGGTCCGGCGGGGGGAGGAGCGGGGGATTTCCCTGCTCATTTCGTTTCCGCTGC
TATGGGTGGGATTGGAGTATGGCCGCGCCTTCCTCGTCACCGGGTTTCCCTGGGCGAGTCTCGGCTACACCCAGTACCGG
ACCCTTCCCCTCATTCAGATCGCCGACATCACCGGGGTCTACGGCCTGAGCTTTCTCATCGCCCTGGCAAACGTGGTCCT
CTTCCGGATCATCCGCGGCTTTGCGGCCCGGGAGCCAGCTCCCTACCCGGTGAAGAGCGTCGTACTCCTGCTCGTGCTGC
TTCTGGTTACCATTGCCTACGGCTTCAAGCGCCTCCATGTCCCCGAGGGCGGTGCGCCGTTCAAGGTGGCCCTCATCCAG
GGAAACATCGACCAGAACATCAAGTGGGATCCGTCGTTCCAGGAGGAAACCGTCGCCATCTACGAGCGGCTGTCGCGCAA
GGCCTGCGCCGCCGGCCCTTCCGATCTTCTGGTTTGGCCCGAAAGCGCGGCCCCGTTTTATTTTCAGGACGAGCCGCGGT
ACGCCTCCCGCATCAAGGGGCTTGCCAGGGAACTCAAAACCTGCGCCGTGGTGGGAAGCCCCGCCTTCGAGAAGGACGGG
GAGCGGCTGAAGTACCTGAACAGCGCCTTTCTCCTTTCCCCGTGGGGGGACGTGATCGGCCGCAGCGACAAGATTCACCT
GGTCCCCTTCGGCGAGTATGTCCCTATGGCAAAACTCCTTCCCTTCGTGAACAAGCTCGTGGCAGGCATCGGCGATTTCT
CGCCCGGTGCGCAGATAGCCGCCCTGGACACCGGCAAGGGGAGGATCGGCATCCTCGTCTGCTTCGAGGGGATATTCCCG
GAACTCTCCCGTGCCTACGTCCGGGCCGGGAGCCGCCTCCTTGTCAACATCACCAACGACGCCTGGTTCGGACGCTCCTC
GGCCCCCTACCAGCATATCTCCATGACCGTCTTCCGTGCCGTGGAGAACCGGGTGCCGCTGGTGCGGGCTGCCAACACCG
GCATAACCTCCATCATCGACAGCAGGGGACACATCCGGGGGATGACCCCTCTCTTCCAAGAGGCGGTGCTGAACGGCGAG
GTGCGGCTGGGGGAGGGTGAGAGCTTCTATAACCGTTATGGCGACGTGTTCGCCTGGGCGTGTGTTGCGGGCGCGGCGGT
GGTTGCGGCCCTTGCTTTCAGAAGAAAGAGTATTCACCATCAATAA

Upstream 100 bases:

>100_bases
ACGACGCTCTTCGGATGACTGTCCTTGAGGGTGGCGAACGGAATATCAGGAAGGTGCGGGTGGCCCGCAGGGCCGGCGCC
TCCGAGGAGACCGAAGGGTA

Downstream 100 bases:

>100_bases
AGGAGTCATGGATGTTCAGAGAAGAAGTAGCCCGCGTTGAAAATCTTTCGGAGCGCATCGCCAAGCTCCGGGGGTCTCTT
TGACATAGACAGCAAGCGGG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRKAFRLGFVTGLAAYAGILYWI
TIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRGEERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYR
TLPLIQIADITGVYGLSFLIALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQ
GNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKGLARELKTCAVVGSPAFEKDG
ERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLLPFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFP
ELSRAYVRAGSRLLVNITNDAWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGE
VRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ

Sequences:

>Translated_521_residues
MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRKAFRLGFVTGLAAYAGILYWI
TIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRGEERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYR
TLPLIQIADITGVYGLSFLIALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQ
GNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKGLARELKTCAVVGSPAFEKDG
ERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLLPFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFP
ELSRAYVRAGSRLLVNITNDAWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGE
VRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ
>Mature_521_residues
MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRKAFRLGFVTGLAAYAGILYWI
TIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRGEERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYR
TLPLIQIADITGVYGLSFLIALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQ
GNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKGLARELKTCAVVGSPAFEKDG
ERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLLPFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFP
ELSRAYVRAGSRLLVNITNDAWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGE
VRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=513, Percent_Identity=29.8245614035088, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_GEOMG (Q39T32)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385317.1
- ProteinModelPortal:   Q39T32
- STRING:   Q39T32
- GeneID:   3740044
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_2367
- NMPDR:   fig|269799.3.peg.2611
- eggNOG:   COG0815
- HOGENOM:   HBG616234
- OMA:   FESYFPE
- PhylomeDB:   Q39T32
- ProtClustDB:   PRK00302
- BioCyc:   GMET269799:GMET_2367-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57387; Mature: 57387

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50263 CN_HYDROLASE

Important sites: ACT_SITE 281-281 ACT_SITE 346-346 ACT_SITE 394-394

Signals:

None

Transmembrane regions:

HASH(0x10b94d60)-; HASH(0x13b770d8)-; HASH(0x13ec8478)-; HASH(0x1336454c)-; HASH(0x14122c28)-; HASH(0x13951bd0)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
AFRLGFVTGLAAYAGILYWITIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYRTLPLIQIADITGVYGLSFLI
CCCCEEEEEHHHHHHHHHHCCCEEEEECCCCHHCCCCHHCCCCEEEEHHHHHHHHHHHHH
ALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHEEECCCCCCCEEEEEEE
GNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCHHHHHHH
LARELKTCAVVGSPAFEKDGERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLL
HHHHHHHHHEECCCCCCCCCHHHHHHHHHHEECCCHHHCCCCCCEEEEECCCCCCHHHHH
PFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFPELSRAYVRAGSRLLVNITND
HHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECHHCHHHHHHHHHCCCEEEEEECCC
AWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGE
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHCCC
VRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MDYRRLRMPDFDAIPRRDYLMAVLSGVLLALSFPSPGISPLAWIAFAPLLLACGRKDPRK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCHHH
AFRLGFVTGLAAYAGILYWITIVVTTYGKLPWIVSVGVLSMLVSYLALYPAVVAYLVRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EERGISLLISFPLLWVGLEYGRAFLVTGFPWASLGYTQYRTLPLIQIADITGVYGLSFLI
CCCCEEEEEHHHHHHHHHHCCCEEEEECCCCHHCCCCHHCCCCEEEEHHHHHHHHHHHHH
ALANVVLFRIIRGFAAREPAPYPVKSVVLLLVLLLVTIAYGFKRLHVPEGGAPFKVALIQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHEEECCCCCCCEEEEEEE
GNIDQNIKWDPSFQEETVAIYERLSRKACAAGPSDLLVWPESAAPFYFQDEPRYASRIKG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCHHHHHHH
LARELKTCAVVGSPAFEKDGERLKYLNSAFLLSPWGDVIGRSDKIHLVPFGEYVPMAKLL
HHHHHHHHHEECCCCCCCCCHHHHHHHHHHEECCCHHHCCCCCCEEEEECCCCCCHHHHH
PFVNKLVAGIGDFSPGAQIAALDTGKGRIGILVCFEGIFPELSRAYVRAGSRLLVNITND
HHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECHHCHHHHHHHHHCCCEEEEEECCC
AWFGRSSAPYQHISMTVFRAVENRVPLVRAANTGITSIIDSRGHIRGMTPLFQEAVLNGE
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHCCC
VRLGEGESFYNRYGDVFAWACVAGAAVVAALAFRRKSIHHQ
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA