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The map label for this gene is exoB [H]

Identifier: 78223532

GI number: 78223532

Start: 2636313

End: 2637320

Strand: Reverse

Name: exoB [H]

Synonym: Gmet_2329

Alternate gene names: 78223532

Gene position: 2637320-2636313 (Counterclockwise)

Preceding gene: 78223533

Following gene: 78223531

Centisome position: 65.98

GC content: 62.7

Gene sequence:

>1008_bases
ATGTCTGAGGTCAGGAAAGGAGAAGGGATGACTGTTCTCGTTACTGGCGGTGCCGGGTACATCGGGAGCCATGTGGTCCG
ACAGCTTTCCGAGGCCGGCTATACCGTGGTTGTCTACGACAATCTCTCCACCGGCTTCGCCGACGCCTTGGTGCATGGCG
AGCGGCTTGTTGTGGGTGAGCTGGCTGATTCTGACCGGCTTGATGCCCTCTTCGCAGAGCACGGGTTCAAGACGGTGCTC
CATTTCGCAGCCTCCATCGTGGCGCCCGAGTCGGTGACCGATCCCCTCAAGTATTACAGCAATAATACCCGCAATACCCT
CAATCTCCTCACGGCCTGCGTGAAGCATGGGGTCGAGCGGTTCATCTTCTCCAGTACCGCGGCGGTGTACGGCATGCCCG
AGAACGGCATTGCTGCGGAAGAGAGTCCCACAGTCCCCATCAACCCCTATGGCACGTCGAAGCTCATGAGTGAATGGATG
CTCCGCGACGTCTGTGCCGCCCATGGCATGCGCTCGGTGGCGCTACGCTACTTCAACGTGGCGGGGGCAGACCCCCAGGC
CCGGATGGGACAGCGGACCCCGGAGGCGACCCACCTCATCAAGGTCTCCAGCCAGGCCGCCCTGGGGATGCGGGAGAAGG
TCTCCATCTTCGGCACCGACTACGCCACCCCCGACGGCACCGGCATCCGCGACTACATCCACATTGAGGATCTTGCCTCA
GCCCACCTGGCTGCCCTGGCGTATCTGGAAAGGGGCGGGGAGACGACGCGGATCAACGTCGGTTATGGCAAGGGGGCCAG
CGTCCGTGAGGTGATCGAGATGGTGCGCCGGGTGTCAGGAGTCCATTTCCCGGCCGAGGAAGCTCCCCGGCGTCCCGGCG
ATCCGGCCATGCTGGTGGCAAAGGCGGACCGGGCCAGGACGGTCCTCGGCTGGACCCCGCACTATGACGATCTTGAAACC
ATTGTCGCCGATGCGTGGCGATGGGAAGCTAAACTCAACAAACGGTGA

Upstream 100 bases:

>100_bases
GCCGACGTGGACGATCTGATGAACGATGTGGGTTTCAAACCGGCCACTCCCATCGGGGAAGGGATACGGCGGTTTGTTGA
GTGGTATCGGGAGTATTACC

Downstream 100 bases:

>100_bases
TTCTATGATCAAGAGTATGACCGGCTACGGCAAGGCCGTGGTCGAAACGGAAACAGGGCGGACCACCGTCGAGATACGGT
CGGTGAACCACCGCTACGGC

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSEVRKGEGMTVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFADALVHGERLVVGELADSDRLDALFAEHGFKTVL
HFAASIVAPESVTDPLKYYSNNTRNTLNLLTACVKHGVERFIFSSTAAVYGMPENGIAAEESPTVPINPYGTSKLMSEWM
LRDVCAAHGMRSVALRYFNVAGADPQARMGQRTPEATHLIKVSSQAALGMREKVSIFGTDYATPDGTGIRDYIHIEDLAS
AHLAALAYLERGGETTRINVGYGKGASVREVIEMVRRVSGVHFPAEEAPRRPGDPAMLVAKADRARTVLGWTPHYDDLET
IVADAWRWEAKLNKR

Sequences:

>Translated_335_residues
MSEVRKGEGMTVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFADALVHGERLVVGELADSDRLDALFAEHGFKTVL
HFAASIVAPESVTDPLKYYSNNTRNTLNLLTACVKHGVERFIFSSTAAVYGMPENGIAAEESPTVPINPYGTSKLMSEWM
LRDVCAAHGMRSVALRYFNVAGADPQARMGQRTPEATHLIKVSSQAALGMREKVSIFGTDYATPDGTGIRDYIHIEDLAS
AHLAALAYLERGGETTRINVGYGKGASVREVIEMVRRVSGVHFPAEEAPRRPGDPAMLVAKADRARTVLGWTPHYDDLET
IVADAWRWEAKLNKR
>Mature_334_residues
SEVRKGEGMTVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFADALVHGERLVVGELADSDRLDALFAEHGFKTVLH
FAASIVAPESVTDPLKYYSNNTRNTLNLLTACVKHGVERFIFSSTAAVYGMPENGIAAEESPTVPINPYGTSKLMSEWML
RDVCAAHGMRSVALRYFNVAGADPQARMGQRTPEATHLIKVSSQAALGMREKVSIFGTDYATPDGTGIRDYIHIEDLASA
HLAALAYLERGGETTRINVGYGKGASVREVIEMVRRVSGVHFPAEEAPRRPGDPAMLVAKADRARTVLGWTPHYDDLETI
VADAWRWEAKLNKR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=40.6528189910979, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=40.6528189910979, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=40.6528189910979, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=26.0450160771704, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657641, Length=324, Percent_Identity=26.8518518518519, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI193211614, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI8393516, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=39.6396396396396, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1790049, Length=265, Percent_Identity=27.1698113207547, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994969, Length=333, Percent_Identity=28.8288288288288, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=28.023598820059, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=38.0813953488372, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=37.7906976744186, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=333, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=250, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=40.8955223880597, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=38.0530973451327, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI21356223, Length=307, Percent_Identity=25.0814332247557, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36440; Mature: 36309

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVRKGEGMTVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFADALVHGERLVVGE
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEE
LADSDRLDALFAEHGFKTVLHFAASIVAPESVTDPLKYYSNNTRNTLNLLTACVKHGVER
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FIFSSTAAVYGMPENGIAAEESPTVPINPYGTSKLMSEWMLRDVCAAHGMRSVALRYFNV
HHHHCCHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
AGADPQARMGQRTPEATHLIKVSSQAALGMREKVSIFGTDYATPDGTGIRDYIHIEDLAS
CCCCHHHHHCCCCCCHHEEEEECCHHHHCHHHHEEEEECCCCCCCCCCCCCEEEHHHHHH
AHLAALAYLERGGETTRINVGYGKGASVREVIEMVRRVSGVHFPAEEAPRRPGDPAMLVA
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEE
KADRARTVLGWTPHYDDLETIVADAWRWEAKLNKR
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEVRKGEGMTVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFADALVHGERLVVGE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEE
LADSDRLDALFAEHGFKTVLHFAASIVAPESVTDPLKYYSNNTRNTLNLLTACVKHGVER
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FIFSSTAAVYGMPENGIAAEESPTVPINPYGTSKLMSEWMLRDVCAAHGMRSVALRYFNV
HHHHCCHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
AGADPQARMGQRTPEATHLIKVSSQAALGMREKVSIFGTDYATPDGTGIRDYIHIEDLAS
CCCCHHHHHCCCCCCHHEEEEECCHHHHCHHHHEEEEECCCCCCCCCCCCCEEEHHHHHH
AHLAALAYLERGGETTRINVGYGKGASVREVIEMVRRVSGVHFPAEEAPRRPGDPAMLVA
HHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEE
KADRARTVLGWTPHYDDLETIVADAWRWEAKLNKR
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]