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The map label for this gene is dfrA [H]

Identifier: 78223527

GI number: 78223527

Start: 2631842

End: 2632219

Strand: Reverse

Name: dfrA [H]

Synonym: Gmet_2324

Alternate gene names: 78223527

Gene position: 2632219-2631842 (Counterclockwise)

Preceding gene: 78223528

Following gene: 78223525

Centisome position: 65.85

GC content: 60.32

Gene sequence:

>378_bases
ATGAAAGAGATTATTGCCACCGACAAGGCACCCAAGGCGATCGGGCCCTATTCTCAGGCAGTGAAGGCGGGGGGCTTCCT
GTTCCTCTCGGGGCAGATACCGCTGGATCCTGCAACCGGAGAATTTGTGCCCGGTGGGATCAGGGAGCAGACCGACCGGG
TCATGGACAATATTGCCGCGGTATTGGCCGAGGCCGGCCTCGGTTTTGACGCCGTCGTGAAGACGACCATCTTTCTGACC
GATCTGGCCAATTTCGGGGTGGTCAACGAGGTGTATGGGAGCCGTTTTTCCGCAGAGCCGCCGGCACGTTCCACGGTGGA
GGTGAAAGGTCTTCCTCGCGGCGCCCTGGTGGAAATCGAGGTGCTTGCCCTCTGCTGA

Upstream 100 bases:

>100_bases
GTCACGAGCCTTGAGCACCTGACCCGGGTCATGAACAACATCATGAAGGTAAGCGGCGTCACCCATGTGGAACGGATGAA
GTCGTAGGAAGGAGCATGCG

Downstream 100 bases:

>100_bases
GAGGTTTCCCCGGGAGAATAAGAAACGACAAAAGCCGCAGACGCGGATGCGCTGCGGCTGAGTCGTTTGTTGGGTGCGGA
AACGTGCCCGAGGGGCAACG

Product: endoribonuclease L-PSP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKEIIATDKAPKAIGPYSQAVKAGGFLFLSGQIPLDPATGEFVPGGIREQTDRVMDNIAAVLAEAGLGFDAVVKTTIFLT
DLANFGVVNEVYGSRFSAEPPARSTVEVKGLPRGALVEIEVLALC

Sequences:

>Translated_125_residues
MKEIIATDKAPKAIGPYSQAVKAGGFLFLSGQIPLDPATGEFVPGGIREQTDRVMDNIAAVLAEAGLGFDAVVKTTIFLT
DLANFGVVNEVYGSRFSAEPPARSTVEVKGLPRGALVEIEVLALC
>Mature_125_residues
MKEIIATDKAPKAIGPYSQAVKAGGFLFLSGQIPLDPATGEFVPGGIREQTDRVMDNIAAVLAEAGLGFDAVVKTTIFLT
DLANFGVVNEVYGSRFSAEPPARSTVEVKGLPRGALVEIEVLALC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family [H]

Homologues:

Organism=Homo sapiens, GI5032215, Length=124, Percent_Identity=43.5483870967742, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87082213, Length=127, Percent_Identity=44.0944881889764, Blast_Score=110, Evalue=4e-26,
Organism=Escherichia coli, GI87082396, Length=127, Percent_Identity=45.6692913385827, Blast_Score=108, Evalue=1e-25,
Organism=Escherichia coli, GI1787245, Length=122, Percent_Identity=27.8688524590164, Blast_Score=59, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25148896, Length=124, Percent_Identity=48.3870967741936, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71982075, Length=124, Percent_Identity=48.3870967741936, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71982068, Length=124, Percent_Identity=48.3870967741936, Blast_Score=121, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6322138, Length=120, Percent_Identity=41.6666666666667, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320899, Length=103, Percent_Identity=40.7766990291262, Blast_Score=84, Evalue=9e-18,
Organism=Drosophila melanogaster, GI19921376, Length=124, Percent_Identity=46.7741935483871, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR006056
- InterPro:   IPR019897 [H]

Pfam domain/function: PF01042 Ribonuc_L-PSP [H]

EC number: NA

Molecular weight: Translated: 13107; Mature: 13107

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIIATDKAPKAIGPYSQAVKAGGFLFLSGQIPLDPATGEFVPGGIREQTDRVMDNIAA
CCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLAEAGLGFDAVVKTTIFLTDLANFGVVNEVYGSRFSAEPPARSTVEVKGLPRGALVEIE
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEE
VLALC
EEEEC
>Mature Secondary Structure
MKEIIATDKAPKAIGPYSQAVKAGGFLFLSGQIPLDPATGEFVPGGIREQTDRVMDNIAA
CCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLAEAGLGFDAVVKTTIFLTDLANFGVVNEVYGSRFSAEPPARSTVEVKGLPRGALVEIE
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEE
VLALC
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA