| Definition | Geobacter metallireducens GS-15 chromosome, complete genome. |
|---|---|
| Accession | NC_007517 |
| Length | 3,997,420 |
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The map label for this gene is ucpA [C]
Identifier: 78223422
GI number: 78223422
Start: 2508676
End: 2509452
Strand: Reverse
Name: ucpA [C]
Synonym: Gmet_2217
Alternate gene names: 78223422
Gene position: 2509452-2508676 (Counterclockwise)
Preceding gene: 78223423
Following gene: 78223421
Centisome position: 62.78
GC content: 53.15
Gene sequence:
>777_bases ATGGGAAGAGTCGAGGGAAAGGTAGCAATTGTCACTGGTGCAGCATCTGGCTTAGGGGCTGCCAGTGCACGGCTTCTTGC GCGCGAGGGAGCAAGGGTCGTAATTACGGATATCAATGTAAAAGATGGTCAGGCGTTGGCTAATTCACTAGGTGAAGGAG CGATCTTTCTGCGGCATGATGTCAGTGACGAGGCGCAGTGGGTTGCCATTATCGAGCAGACGTTGTCACGCTTCGGACGC CTGGACATCTTGGTTAATAACGCGGGTGTGGTGGTTGTGGCTGATGTTGAACACACGACAGTGGAAGATTGGCGTTTTGT CAATGCCGTCGGCACGGACGGTACATTCTTCGGTTGCAAGCATGCCATACCAGCAATGCGAAGATCGGGGGGAGGATCTA TCGTCAATCTGTCATCCCTTGCCGGCATCGGCGGCTATCCCCTTGTGTTTGCCTATTCCGCTTCCAAGGGGGCGATTCGT GCCATGACCAAATCCGTTGCTGTCCATTGTGCCCAGAATAAATACAATATCCGGTGCAACTCCATTCATCCGGGGGGGAT CCTCACCCCCTTGGTTGAAGGATTTATCAAGTCGGCGGTTGGTACTGCGGATGCAAGTATGGACAAAGCACGGGACCTGT TTTCCAAGTTGGGTGAGCCTGATGATGTTGCCTACATGGTCTTGTACCTGGCGTCGGACGAGTCTAAGTTTGTGAGCGGC TCCGAGTTCATCATTGATAACACGGCAACAATTACCGAGGGAGTAGTGCCGACGTAG
Upstream 100 bases:
>100_bases CATGTTGGCCTAGCAGGTACTATTCAAGTAATGGTGTATGGTGTGTACAATAGGGGCACGTTTAGTGCCATAGACTGATG GTCTAAAAAGGAGTAAGGAT
Downstream 100 bases:
>100_bases GCGGCTCGGTCCGTGCCTTATTGCTTGATCCGGAAATATATTCGGGTTGTTTCCTGGAAACTCGCTCCCATGGTGCGTCA CCGGGAACCTTTGGTGGAAT
Product: Short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MGRVEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHDVSDEAQWVAIIEQTLSRFGR LDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCKHAIPAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIR AMTKSVAVHCAQNKYNIRCNSIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMVLYLASDESKFVSG SEFIIDNTATITEGVVPT
Sequences:
>Translated_258_residues MGRVEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHDVSDEAQWVAIIEQTLSRFGR LDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCKHAIPAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIR AMTKSVAVHCAQNKYNIRCNSIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMVLYLASDESKFVSG SEFIIDNTATITEGVVPT >Mature_257_residues GRVEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHDVSDEAQWVAIIEQTLSRFGRL DILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCKHAIPAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIRA MTKSVAVHCAQNKYNIRCNSIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMVLYLASDESKFVSGS EFIIDNTATITEGVVPT
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=35.7446808510638, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=36.2903225806452, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=28.740157480315, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI31542939, Length=245, Percent_Identity=33.469387755102, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=30.5785123966942, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.5490196078431, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=38.0116959064327, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4504505, Length=242, Percent_Identity=30.1652892561983, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=30.859375, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=30.5019305019305, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40254986, Length=271, Percent_Identity=27.3062730627306, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI20149619, Length=234, Percent_Identity=31.6239316239316, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI310128830, Length=207, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI310115468, Length=207, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7706318, Length=246, Percent_Identity=28.8617886178862, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI209862901, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI19923983, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=25.7692307692308, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7657478, Length=255, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI210032110, Length=158, Percent_Identity=31.0126582278481, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=31.5217391304348, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=32.994923857868, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=34.9809885931559, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=29.6747967479675, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.8775510204082, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=30.1652892561983, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=30.0813008130081, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=30.9917355371901, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=27.0491803278689, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=32.1138211382114, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=29.8039215686275, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=32.2463768115942, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=31.3653136531365, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=29.8181818181818, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=280, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=29.9638989169675, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.4132841328413, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=32.6848249027237, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=34.2857142857143, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=34.297520661157, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=30.241935483871, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=32.2314049586777, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=29.1512915129151, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.9803921568627, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17560220, Length=281, Percent_Identity=28.4697508896797, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17551412, Length=278, Percent_Identity=28.4172661870504, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17538480, Length=283, Percent_Identity=28.9752650176678, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=32.3770491803279, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=28.6231884057971, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=28.4671532846715, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=26.7148014440433, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI72000259, Length=277, Percent_Identity=28.158844765343, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=31.1224489795918, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=28.2608695652174, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=30.03663003663, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71982365, Length=282, Percent_Identity=28.0141843971631, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.6932270916335, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17555612, Length=263, Percent_Identity=30.7984790874525, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=27.1739130434783, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=25.3886010362694, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17561272, Length=259, Percent_Identity=30.8880308880309, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17558628, Length=269, Percent_Identity=24.907063197026, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=29.9595141700405, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=26.6932270916335, Blast_Score=62, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=24.8995983935743, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=36.0323886639676, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=118, Evalue=3e-27, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=33.9920948616601, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=30.6772908366534, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.8548387096774, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=33.0612244897959, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=31.640625, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=30.6451612903226, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21358495, Length=234, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=30.0411522633745, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=29.5275590551181, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=28.7128712871287, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI281364892, Length=187, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357673, Length=147, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24663911, Length=259, Percent_Identity=26.6409266409266, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=29.4605809128631, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24640492, Length=196, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24648944, Length=229, Percent_Identity=29.6943231441048, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.51 [H]
Molecular weight: Translated: 27032; Mature: 26901
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGRVEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHD CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEEC VSDEAQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCK CCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCEEEEEEECCCCCEECHH HAIPAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIRAMTKSVAVHCAQNKYNIRCN HHHHHHHHCCCCCEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEEECCCCEEEEC SIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMVLYLASDESKFVSG CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEECC SEFIIDNTATITEGVVPT CEEEEECCCCCCCCCCCC >Mature Secondary Structure GRVEGKVAIVTGAASGLGAASARLLAREGARVVITDINVKDGQALANSLGEGAIFLRHD CCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCEEEEEEC VSDEAQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCK CCCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCEEEEEEECCCCCEECHH HAIPAMRRSGGGSIVNLSSLAGIGGYPLVFAYSASKGAIRAMTKSVAVHCAQNKYNIRCN HHHHHHHHCCCCCEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHEEEECCCCEEEEC SIHPGGILTPLVEGFIKSAVGTADASMDKARDLFSKLGEPDDVAYMVLYLASDESKFVSG CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEECC SEFIIDNTATITEGVVPT CEEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8382516; 2026158; 8617258 [H]