BacMap

Definition	Geobacter metallireducens GS-15 chromosome, complete genome.
Accession	NC_007517
Length	3,997,420

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The map label for this gene is fadB1 [H]

Identifier: 78223278

GI number: 78223278

Start: 2330299

End: 2331081

Strand: Reverse

Name: fadB1 [H]

Synonym: Gmet_2071

Alternate gene names: 78223278

Gene position: 2331081-2330299 (Counterclockwise)

Preceding gene: 78223279

Following gene: 78223277

Centisome position: 58.31

GC content: 61.94

Gene sequence:

>783_bases
ATGGGAACCGAGAATCTGCTTGTTGACATAAAAGACGGCGTGGCCCTGCTGACCATCAACCGGCCCAAGGTGCTGAACGC
CCTCCACACCTCGGTGATCGCCGAGTTGCAGGAAACCTTCGAAGCGTTGAACGCCAACCAGGCTGTCAAGGCGGTCGTTA
TCACGGGCAGCGGCGAGAAGGCCTTTGTGGCCGGAGCCGACATTGCCGAGATGGCGGTCATGGACGCCCAGCAGGCCCTC
GTTTTCGCCCGCACGGGACAGAAGCTGGTGAACTACATCGGCACCATGCCCAAGCCGGTCATAGCCGCCGTCAACGGTTT
TGCCCTGGGGGGAGGGATGGAACTGGCCCTGGCCTGCGATTTCATCTACGCCTCGGAAAACGCCAAGATGGGACTGCCGG
AGGTGACCCTCGGGATCATGCCCGGGTTCGGCGGTTCCCAGAAGTTCGCCCGGCTCCTGGGGCGCAGTCGGGCCAACGAG
TTGATTTTCACCGGCAAGATGCTGACTGCCGCCGAAGCGAAGGAGTGGGGGATCGTCAACGCCGTCTTACCGCTTGCGGA
GCTGGTGGGAAAGGCCCTTGAGACGGCCGCGAGAATTGCCGGCAACGGCCTCCTCGGGGTCGCCCATGTCAAGGAAGCCA
TCCGCCGGGGCCTCGATATGACGGAACCGGACGGCATGGACTACGAGTCGGTCCTTTTTGCCTCCCTCTTCGCCTCCCGT
GACCAGAAGGAAGGTATGGGGGCTTTTGTGGAAAAGCGGAAACCGAACTTTACCGGGTCGTAA

Upstream 100 bases:

>100_bases
AGTACCGCCCCTGTCCGCTCCTGGTCAAGATGGTGGAGGCCGGGTATCTGGGGAGGAAGACGGGGCGGGGATTCTACACC
TACTGATTGGGGGAAATGCC

Downstream 100 bases:

>100_bases
GATTGTTCGAGATGTGAACCTATTAACACTATTGGAGATTGAGCCATGGAAGCTACCCGCGAACTCTATTGGAATATCGG
CCACGGGGCATCGGTCCTTA

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGTENLLVDIKDGVALLTINRPKVLNALHTSVIAELQETFEALNANQAVKAVVITGSGEKAFVAGADIAEMAVMDAQQAL
VFARTGQKLVNYIGTMPKPVIAAVNGFALGGGMELALACDFIYASENAKMGLPEVTLGIMPGFGGSQKFARLLGRSRANE
LIFTGKMLTAAEAKEWGIVNAVLPLAELVGKALETAARIAGNGLLGVAHVKEAIRRGLDMTEPDGMDYESVLFASLFASR
DQKEGMGAFVEKRKPNFTGS

Sequences:

>Translated_260_residues
MGTENLLVDIKDGVALLTINRPKVLNALHTSVIAELQETFEALNANQAVKAVVITGSGEKAFVAGADIAEMAVMDAQQAL
VFARTGQKLVNYIGTMPKPVIAAVNGFALGGGMELALACDFIYASENAKMGLPEVTLGIMPGFGGSQKFARLLGRSRANE
LIFTGKMLTAAEAKEWGIVNAVLPLAELVGKALETAARIAGNGLLGVAHVKEAIRRGLDMTEPDGMDYESVLFASLFASR
DQKEGMGAFVEKRKPNFTGS
>Mature_259_residues
GTENLLVDIKDGVALLTINRPKVLNALHTSVIAELQETFEALNANQAVKAVVITGSGEKAFVAGADIAEMAVMDAQQALV
FARTGQKLVNYIGTMPKPVIAAVNGFALGGGMELALACDFIYASENAKMGLPEVTLGIMPGFGGSQKFARLLGRSRANEL
IFTGKMLTAAEAKEWGIVNAVLPLAELVGKALETAARIAGNGLLGVAHVKEAIRRGLDMTEPDGMDYESVLFASLFASRD
QKEGMGAFVEKRKPNFTGS

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=244, Percent_Identity=45.0819672131148, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=37.0517928286853, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=32.4110671936759, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI68989263, Length=236, Percent_Identity=33.0508474576271, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=33.1491712707182, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI70995211, Length=251, Percent_Identity=30.6772908366534, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=32.9032258064516, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=32.9032258064516, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI45643119, Length=222, Percent_Identity=30.6306306306306, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI260275230, Length=222, Percent_Identity=30.6306306306306, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI260274832, Length=222, Percent_Identity=30.6306306306306, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI25453481, Length=258, Percent_Identity=24.8062015503876, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI51538573, Length=258, Percent_Identity=24.8062015503876, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4757968, Length=258, Percent_Identity=24.8062015503876, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI49355787, Length=258, Percent_Identity=24.8062015503876, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4757966, Length=247, Percent_Identity=24.6963562753036, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI51538581, Length=247, Percent_Identity=24.6963562753036, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI221136756, Length=258, Percent_Identity=23.6434108527132, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI221136753, Length=258, Percent_Identity=23.6434108527132, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI221307494, Length=258, Percent_Identity=23.6434108527132, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI62530384, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116235487, Length=232, Percent_Identity=23.7068965517241, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI261878539, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI157694516, Length=208, Percent_Identity=25, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI213417737, Length=208, Percent_Identity=25, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=40.5511811023622, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=38.3141762452107, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=39.7905759162304, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788597, Length=266, Percent_Identity=28.9473684210526, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790281, Length=206, Percent_Identity=37.8640776699029, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082183, Length=250, Percent_Identity=31.2, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=33.4615384615385, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=47.7911646586345, Blast_Score=223, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=46.9879518072289, Blast_Score=214, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=36, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17558304, Length=197, Percent_Identity=39.0862944162437, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534483, Length=268, Percent_Identity=26.865671641791, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=30.078125, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17508951, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17508953, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144160, Length=193, Percent_Identity=32.6424870466321, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=25.2918287937743, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25144157, Length=193, Percent_Identity=32.6424870466321, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=214, Percent_Identity=29.9065420560748, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=186, Percent_Identity=30.1075268817204, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=27.0916334661355, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25141363, Length=173, Percent_Identity=26.5895953757225, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=185, Percent_Identity=28.1081081081081, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=42.1052631578947, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=42.1052631578947, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=36.6037735849057, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI19922422, Length=252, Percent_Identity=29.3650793650794, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=31.640625, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357171, Length=263, Percent_Identity=27.7566539923954, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24583077, Length=202, Percent_Identity=33.6633663366337, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583079, Length=202, Percent_Identity=33.6633663366337, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921000, Length=200, Percent_Identity=34, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650670, Length=254, Percent_Identity=25.9842519685039, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19921018, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24654903, Length=210, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24583165, Length=173, Percent_Identity=30.0578034682081, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571729, Length=143, Percent_Identity=30.0699300699301, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571730, Length=143, Percent_Identity=30.0699300699301, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550169, Length=175, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27415; Mature: 27284

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTENLLVDIKDGVALLTINRPKVLNALHTSVIAELQETFEALNANQAVKAVVITGSGEK
CCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
AFVAGADIAEMAVMDAQQALVFARTGQKLVNYIGTMPKPVIAAVNGFALGGGMELALACD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEECCCCEEEEEEE
FIYASENAKMGLPEVTLGIMPGFGGSQKFARLLGRSRANELIFTGKMLTAAEAKEWGIVN
EEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHH
AVLPLAELVGKALETAARIAGNGLLGVAHVKEAIRRGLDMTEPDGMDYESVLFASLFASR
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
DQKEGMGAFVEKRKPNFTGS
CCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
GTENLLVDIKDGVALLTINRPKVLNALHTSVIAELQETFEALNANQAVKAVVITGSGEK
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
AFVAGADIAEMAVMDAQQALVFARTGQKLVNYIGTMPKPVIAAVNGFALGGGMELALACD
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEECCCCEEEEEEE
FIYASENAKMGLPEVTLGIMPGFGGSQKFARLLGRSRANELIFTGKMLTAAEAKEWGIVN
EEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCHHH
AVLPLAELVGKALETAARIAGNGLLGVAHVKEAIRRGLDMTEPDGMDYESVLFASLFASR
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
DQKEGMGAFVEKRKPNFTGS
CCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]