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The map label for this gene is 78223268

Identifier: 78223268

GI number: 78223268

Start: 2316532

End: 2318547

Strand: Direct

Name: 78223268

Synonym: Gmet_2061

Alternate gene names: NA

Gene position: 2316532-2318547 (Clockwise)

Preceding gene: 78223255

Following gene: 78223269

Centisome position: 57.95

GC content: 58.09

Gene sequence:

>2016_bases
ATGATCCCGATTGAGATCGTTTCCACACTATCTCTCCTTTATATTGGCCTTCTGTATGCCGTAGCCTATTTTGCCGACAG
ACGGCATGAGGCCGGCCGGAGCATCGTTGCCAACTCCTTCGTCTATTCCCTCTCCCTGGCCGTCATTTACACATCATGGA
CCTTTTACGGTTCCGTGGGACGGGCCGCCACCAGCGGCATCGAATTCCTCACCGACAGCCTGGGGATAACCCTCATGGCC
TTCTGCTGGTGGTTCCTGCTGCGGAAGATGGTGCGGGTCAGCAAGGAGCAGAACGTTCGCAGCATCGCCGATTTCATCTC
CAGCCGCTACGGAAAGTCACCGCTCCTGGGGGCGGTCGTCACCATTATCGTCATTGCGGCGTTCCCTCCGTACATTGCCC
TGCAACTTAAAGCAGTGGCCCACACCTTCGATCTCCTCACAAAACCGCCCCACATCGCCGGCGGTCTGAACAATCTCATC
CCCGCGCTCCCCCCTTTCGTGGATACCGCGTTCATTGTCACCCTGTTCCTCGCCCTTTTCGGCGTCCTGTTCGGAGCACG
GCACCTGGACGTCTCCGAGCGCCACGAGGGGCTGGTGGCCGCCATCGCCCTGCAATCGGTGGTCAAGCTCGTCGCCTTCG
TCACCGTGGGGCTGTTTGTCACCTATGGCCTGTTCGACGGCTTCAGTGATATCTTCTCACGCTTTATCGCCCGATTCCCC
GACCGCACAGACCTCTTTCTCCTGGGGACACCCCATGTTCCCCATTCGTTATGGTTATCCCGAGTATTGATGATCATGAT
TTCGTTCATGTTCCTCCCCCGCATGTTCCATGTCATGGTTATCGAGAATGCCGACGAGGGGCACATTAAAGACGCCATGT
GGCACCTCCCCACCTATGCCTTTCTCCTCGCCCTGTTCGTGCTGCCCGTAGCCCTGGGAGGCATCATCCTCAGCGGAGGG
GATACCGCCATGGCCGACTTTTTTGTTATCCACCTCCCCTTGGAGTCCGGTCATCCCTGGCTGGCCCTGTTGGCTTTCAT
AGGAGGCTTTTCCGCTTCGGCGGGCATGGTCATCGTCGAATCGGTGGTGCTCTCCACCATGATTCTCGACCATCTGGCCT
TGCCGGTCATTCTGAAGCTCAGGGTGGAAGCCTCGGACATGTCGAAAGTTCTCCTGAACATCAAACGGGCAGGGATCATT
GCCATCGTCTTTTTCGGCTACCTCTACTACCGGTTCATCAGCGAATCATACGCACTGATCAACACCGGTGTCGTCACGTT
CATCGCCGTGGCCCAGTTCGCGCCGTCCGTCATCGGGGGGCTCTTCTGGAAGCGTGCCAATCGTCGCGGGGCGCTGACCG
GTATCCTGCTGGGATTCGTCGTCTGGTTCTACACCCTGCTGATTCCCCTCTTTATCAACTCGGGCTGGCTGCCTGACGAT
CTCCTTGATAACGGCCCCTTCGGCCTCGGATTTCTGCGCCCCCAGGAACTGTTTGGCCTGAGTGGTCTCGACATGATCTC
CCACGCCCTGTTCTGGACCCTGTTCTTTAACCTGGGGGCTTTCGTTGCCTTTTCCCTCCTGAGCGACCCGGACGACAGCG
GAACCGAACAGGCAGTGAAATTCGTGGATGTTTTCGAGGTGCGCGATGAGTCGGTCACGCGCAAGAGGATGAGCAAGTCC
TTCGCCGTCGTGGAATTCGTGGATCTGATGACCAAGTTCATCGGCCAGGACCAGGCCCACGCCGCCATCGCCCGATTCCT
CAAACACAAGCAGATCGATGAAAAGGGAAGCCTCTCGGAATACGAGCTTCCCATCCTGAAGCGGTATACCGAGAAGGTTC
TGGCCGGTTCGGTGGGGGCAGCATCGGCGGGGATCATCGTGGACAGCTATCTGGCTGCGCGGGGAAGTGAACTTGAGGAC
GTTTTCGACATTTTCGGTACGGTTTCCCTCAGCCGCACCGCCAGCAGGGAACAACTTGGCGTTCTCTACGAGGCTGCGCG
GTTAGTGGCGACCTGA

Upstream 100 bases:

>100_bases
GACACCCGACAGCTTCCAAGGACCGATACCGGTCCGCTTGCCTGGATGCCCGGAATGGATGAAGCGCCACAGAAGATTCG
GCAGAGAGGGAATCCCGAGG

Downstream 100 bases:

>100_bases
AGACCATCCTGGACAGCATCCTGGAGCTTCTCCAGCAGCAGTTCAAGTTCGACACGTGCGTTATCCGCATTCTCGACGAA
GAAATGAAGACTCTTACCGT

Product: Na+/solute symporter

Products: NA

Alternate protein names: Multi-Sensor Hybrid Histidine Kinase; Integral Membrane Sensor Hybrid Histidine Kinase; Periplasmic Sensor Hybrid Histidine Kinase; Two-Component Sensor; ATPase Histidine Kinase- DNA Gyrase B- And; Multi-Sensor Signal Transduction Histidine Kinase; Two-Component Hybrid Sensor And Regulator; Histidine Kinase; Na+/Proline Symporter; Periplasmic Sensor Signal Transduction Histidine Kinase; Sensory Box Histidine Kinase/Response Regulator; Sensory Box Sensor Histidine Kinase/Response Regulator; Sensor Histidine Kinase Proline Sensor PrlS; Serine Phosphatase; Sensor Protein; Response Regulator Receiver; Sensory Box Histidine Kinase; PAS/PAC Sensor Hybrid Histidine Kinase; Two-Component System Sensor Protein; Two-Component Sensor Kinase CbrA; PAS Sensor Protein; Two-Component Sensor Histidine Kinase; Phytochrome Sensor Protein; Na+/Solute Symporter; Two Component Sensor Kinase/Response Regulator Hybrid; Two-Component Sensor CbrA; Sensor Histidine Kinase/Response Regulator; Integral Membrane Sensor Hybrid Histidine Protein Kinase; GalS His Kinase A Domain; Na-Solute Symporter/Sensory Box Histidinekinase; Sodium-Solute Symporter/Sensor Histidine Kinase; Two-Component System Sensor/Regulator Hybrid Protein; Diguanylate Cyclase/Phosphodiesterase; Na+/Proline Symporter-Like Protein; GAF Sensor Signal Transduction Histidine Kinase; PAS Fold Family; Signal Transduction Histidinekinase; Membrane Associated Response Regulator Histidine Kinase; GAF Sensor Protein; Sensory Transduction Histidine Kinase; Stage II Sporulation Protein E; Sensory Histidine Protein Kinase CbrA; Signal Transduction Histidine Kinase; PAS Fold Family Protein; Na+/Solute Symporter / Histidine Kinase; Two Component Sensor Signal Transduction Histidine Kinase; Proline Sensor PrlS

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MIPIEIVSTLSLLYIGLLYAVAYFADRRHEAGRSIVANSFVYSLSLAVIYTSWTFYGSVGRAATSGIEFLTDSLGITLMA
FCWWFLLRKMVRVSKEQNVRSIADFISSRYGKSPLLGAVVTIIVIAAFPPYIALQLKAVAHTFDLLTKPPHIAGGLNNLI
PALPPFVDTAFIVTLFLALFGVLFGARHLDVSERHEGLVAAIALQSVVKLVAFVTVGLFVTYGLFDGFSDIFSRFIARFP
DRTDLFLLGTPHVPHSLWLSRVLMIMISFMFLPRMFHVMVIENADEGHIKDAMWHLPTYAFLLALFVLPVALGGIILSGG
DTAMADFFVIHLPLESGHPWLALLAFIGGFSASAGMVIVESVVLSTMILDHLALPVILKLRVEASDMSKVLLNIKRAGII
AIVFFGYLYYRFISESYALINTGVVTFIAVAQFAPSVIGGLFWKRANRRGALTGILLGFVVWFYTLLIPLFINSGWLPDD
LLDNGPFGLGFLRPQELFGLSGLDMISHALFWTLFFNLGAFVAFSLLSDPDDSGTEQAVKFVDVFEVRDESVTRKRMSKS
FAVVEFVDLMTKFIGQDQAHAAIARFLKHKQIDEKGSLSEYELPILKRYTEKVLAGSVGAASAGIIVDSYLAARGSELED
VFDIFGTVSLSRTASREQLGVLYEAARLVAT

Sequences:

>Translated_671_residues
MIPIEIVSTLSLLYIGLLYAVAYFADRRHEAGRSIVANSFVYSLSLAVIYTSWTFYGSVGRAATSGIEFLTDSLGITLMA
FCWWFLLRKMVRVSKEQNVRSIADFISSRYGKSPLLGAVVTIIVIAAFPPYIALQLKAVAHTFDLLTKPPHIAGGLNNLI
PALPPFVDTAFIVTLFLALFGVLFGARHLDVSERHEGLVAAIALQSVVKLVAFVTVGLFVTYGLFDGFSDIFSRFIARFP
DRTDLFLLGTPHVPHSLWLSRVLMIMISFMFLPRMFHVMVIENADEGHIKDAMWHLPTYAFLLALFVLPVALGGIILSGG
DTAMADFFVIHLPLESGHPWLALLAFIGGFSASAGMVIVESVVLSTMILDHLALPVILKLRVEASDMSKVLLNIKRAGII
AIVFFGYLYYRFISESYALINTGVVTFIAVAQFAPSVIGGLFWKRANRRGALTGILLGFVVWFYTLLIPLFINSGWLPDD
LLDNGPFGLGFLRPQELFGLSGLDMISHALFWTLFFNLGAFVAFSLLSDPDDSGTEQAVKFVDVFEVRDESVTRKRMSKS
FAVVEFVDLMTKFIGQDQAHAAIARFLKHKQIDEKGSLSEYELPILKRYTEKVLAGSVGAASAGIIVDSYLAARGSELED
VFDIFGTVSLSRTASREQLGVLYEAARLVAT
>Mature_671_residues
MIPIEIVSTLSLLYIGLLYAVAYFADRRHEAGRSIVANSFVYSLSLAVIYTSWTFYGSVGRAATSGIEFLTDSLGITLMA
FCWWFLLRKMVRVSKEQNVRSIADFISSRYGKSPLLGAVVTIIVIAAFPPYIALQLKAVAHTFDLLTKPPHIAGGLNNLI
PALPPFVDTAFIVTLFLALFGVLFGARHLDVSERHEGLVAAIALQSVVKLVAFVTVGLFVTYGLFDGFSDIFSRFIARFP
DRTDLFLLGTPHVPHSLWLSRVLMIMISFMFLPRMFHVMVIENADEGHIKDAMWHLPTYAFLLALFVLPVALGGIILSGG
DTAMADFFVIHLPLESGHPWLALLAFIGGFSASAGMVIVESVVLSTMILDHLALPVILKLRVEASDMSKVLLNIKRAGII
AIVFFGYLYYRFISESYALINTGVVTFIAVAQFAPSVIGGLFWKRANRRGALTGILLGFVVWFYTLLIPLFINSGWLPDD
LLDNGPFGLGFLRPQELFGLSGLDMISHALFWTLFFNLGAFVAFSLLSDPDDSGTEQAVKFVDVFEVRDESVTRKRMSKS
FAVVEFVDLMTKFIGQDQAHAAIARFLKHKQIDEKGSLSEYELPILKRYTEKVLAGSVGAASAGIIVDSYLAARGSELED
VFDIFGTVSLSRTASREQLGVLYEAARLVAT

Specific function: Unknown

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 73919; Mature: 73919

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA