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The map label for this gene is coaX

Identifier: 78223193

GI number: 78223193

Start: 2216008

End: 2216775

Strand: Reverse

Name: coaX

Synonym: Gmet_1986

Alternate gene names: 78223193

Gene position: 2216775-2216008 (Counterclockwise)

Preceding gene: 78223194

Following gene: 78223192

Centisome position: 55.46

GC content: 57.55

Gene sequence:

>768_bases
ATGCTTCTCGTCATAGACGTGGGCAACACGAATATCGTTCTCGGCATCTATGACGGTCAGAGGCTTGTGCGTGACTGGCG
CATATCCACCGACAAGGCCAAAACGTCAGACGAGTACGGAATCCTGATCCGTGAGCTTTTCCGTGGCGCCGACATCGAAT
TCAAGGATGTGAAGGCCATTATTATTTCTTCGGTGGTGCCGACCCTGTCCGGAGTTCTGGAACGGCTTTCCCGGAACTAC
TTCGGCTACAGTCCCCTTGTGGTTGGGCCGGGGATCAGGACCGGCATGCCGATCCAGTACGACAATCCCAAGGAGGTGGG
GGCGGACCGGATTGTCAATGCGGTGGCAGGCTACGAGAAGTACAAGACGTCTCTGGTCATCGTCGATTTTGGCACCGCCA
CCACCTTTGATTACGTGAACCGCAAGGGAGAATACTGCGGCGGCGCCATCGCCCCAGGGCTTGTCATATCTATGGAGGCC
CTGTTCCAGAGGGCGAGCAAGCTTCCCCGCGTCGATATCGTGAAGCCTCCGGCAGTCATTGCCCGCAATACGGTCAATTC
CATGCAGGCCGGCATCTTTTATGGGTATGTGGGGCTTGTGGACGAGATCGTGGCCAGGATGAAAGCAGAGAGCAAGGAAA
CTCCACGGGTCATCGCCACGGGGGGGCTTGCCGGGCTGATCGCCCCCGAGTCAAAAACCATCGAGGCGGTGGAGGAGTAC
CTCACGCTGGAGGGACTGCGGATACTGTACGAACGAAACAGGGAGTGA

Upstream 100 bases:

>100_bases
TGCTGAGAACCGCTCATGGCACCCTTGAGCGGGTTCTGGCAGGGGATGTGACAATTGAAGGGTAAGGTGGCGCCGTGCTT
TCTGTTCTGGAGGTAAACCC

Downstream 100 bases:

>100_bases
GATGACGAGATAGCGCGGAAGTCAAAAGGTCGCCAGACCTATACCTTATCATCACGGGAGGATGTATGGGCAAGTATGAT
ACCGCAAAGCTGAGAAACCT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLLVIDVGNTNIVLGIYDGQRLVRDWRISTDKAKTSDEYGILIRELFRGADIEFKDVKAIIISSVVPTLSGVLERLSRNY
FGYSPLVVGPGIRTGMPIQYDNPKEVGADRIVNAVAGYEKYKTSLVIVDFGTATTFDYVNRKGEYCGGAIAPGLVISMEA
LFQRASKLPRVDIVKPPAVIARNTVNSMQAGIFYGYVGLVDEIVARMKAESKETPRVIATGGLAGLIAPESKTIEAVEEY
LTLEGLRILYERNRE

Sequences:

>Translated_255_residues
MLLVIDVGNTNIVLGIYDGQRLVRDWRISTDKAKTSDEYGILIRELFRGADIEFKDVKAIIISSVVPTLSGVLERLSRNY
FGYSPLVVGPGIRTGMPIQYDNPKEVGADRIVNAVAGYEKYKTSLVIVDFGTATTFDYVNRKGEYCGGAIAPGLVISMEA
LFQRASKLPRVDIVKPPAVIARNTVNSMQAGIFYGYVGLVDEIVARMKAESKETPRVIATGGLAGLIAPESKTIEAVEEY
LTLEGLRILYERNRE
>Mature_255_residues
MLLVIDVGNTNIVLGIYDGQRLVRDWRISTDKAKTSDEYGILIRELFRGADIEFKDVKAIIISSVVPTLSGVLERLSRNY
FGYSPLVVGPGIRTGMPIQYDNPKEVGADRIVNAVAGYEKYKTSLVIVDFGTATTFDYVNRKGEYCGGAIAPGLVISMEA
LFQRASKLPRVDIVKPPAVIARNTVNSMQAGIFYGYVGLVDEIVARMKAESKETPRVIATGGLAGLIAPESKTIEAVEEY
LTLEGLRILYERNRE

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_GEOMG (Q39U59)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384940.1
- ProteinModelPortal:   Q39U59
- SMR:   Q39U59
- STRING:   Q39U59
- GeneID:   3739208
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1986
- NMPDR:   fig|269799.3.peg.1599
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   GMET269799:GMET_1986-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28029; Mature: 28029

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNTNIVLGIYDGQRLVRDWRISTDKAKTSDEYGILIRELFRGADIEFKDVKAI
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
IISSVVPTLSGVLERLSRNYFGYSPLVVGPGIRTGMPIQYDNPKEVGADRIVNAVAGYEK
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YKTSLVIVDFGTATTFDYVNRKGEYCGGAIAPGLVISMEALFQRASKLPRVDIVKPPAVI
HCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHH
ARNTVNSMQAGIFYGYVGLVDEIVARMKAESKETPRVIATGGLAGLIAPESKTIEAVEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHH
LTLEGLRILYERNRE
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLVIDVGNTNIVLGIYDGQRLVRDWRISTDKAKTSDEYGILIRELFRGADIEFKDVKAI
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
IISSVVPTLSGVLERLSRNYFGYSPLVVGPGIRTGMPIQYDNPKEVGADRIVNAVAGYEK
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YKTSLVIVDFGTATTFDYVNRKGEYCGGAIAPGLVISMEALFQRASKLPRVDIVKPPAVI
HCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHH
ARNTVNSMQAGIFYGYVGLVDEIVARMKAESKETPRVIATGGLAGLIAPESKTIEAVEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHH
LTLEGLRILYERNRE
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA