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The map label for this gene is trpS [H]

Identifier: 78223167

GI number: 78223167

Start: 2184903

End: 2185889

Strand: Reverse

Name: trpS [H]

Synonym: Gmet_1960

Alternate gene names: 78223167

Gene position: 2185889-2184903 (Counterclockwise)

Preceding gene: 78223168

Following gene: 78223166

Centisome position: 54.68

GC content: 59.98

Gene sequence:

>987_bases
ATGAGCAACAAGCGGATAGTCAGCGGCATGAGGCCAACCGGAAAACTCCACCTTGGCCACTTCCACGGCGTGCTCGCCAA
CTGGCGGGAACTCCAGGAAGAGTATGAATGCTTCTTCTTCGCTGCCGACTGGCACTCCCTTACCACTGAATACGACAACA
CCGCAGGTATACGTCAGAACACCGACGAGATGATCCTCGACTGGCTTGCCTTCGGGGTCGATCCCGCCAAGTGCGTTATC
TTCCGGCAGAGCCGCGTACCCCAGCACGCGGAACTGAACCTGATCCTTTCCATGATCACGCCGGTTTCATGGCTTGAGCG
GAACCCCACCTACAAGGAGATGCAGGAGAATCTTTCCACCAAGGATCTCTCCACCTTCGGTTTTCTCGGCTATCCGGTCC
TCATGGCGTCGGACATCATCGTCTACAAGGCATCCAAGGTTCCGGTGGGGCACGATCAGCTCCCCCACTTGGAGATTACC
CGCGAGATCGCACGGCGCTTCAACTACCTCTACAACAGAGAGGTCTTCCCTGAGCCCGCGGCGCTCCTCACCGAGACGCC
CAAGGTGCTGGGGCTCGACGGCCGCAAGATGAGCAAGTCCTACGGCAATGCCATTTTTCTCTCGGAGAGTGCCGAAGAAA
CCCGCAAGAAGGTGATGTCGATGGTTACCGATACTCAGCGGGTCCGGCGGAGCGATCCGGGGGAGCCCGACCGTTGTGTT
GCCTTTTCCCTCAACAGCCTCTACCTCCCCGAAGAAAAGAAGGCAGACATCTACGCAGGGTGCCGCAGTGCCGCCATTGG
TTGCGTTGAGTGCAAGAAGCTCCAGGCCGAGTACCTGGTCCAGACCCTTGCCCCCTACCGGGCACGCCGCGACGAACTCA
CCGAAAAGCCGGGGCTCGTGGCCGAAATCCTTGCCGAAGGGGAGGCCCGTGCCGCAACCGAGGCCGCGCGAACCATGGCC
GAGGTGCGGGACGCCCTCAATCTATGA

Upstream 100 bases:

>100_bases
GGGATCCGTATTCTTGCCGGGCCTCAAAGCGGTCTGGTGTACAGCGTTACCCACTTTCTCATGAGATAAACGGCACAGCC
GTCGATAAAAGGAGCAGACG

Downstream 100 bases:

>100_bases
GCAACGGCGGGAATCTTGACCTCTACCAGGATGAGGAGAGCCCCTCCTATACGGTGAAGCTCGAGGTCTTCGAGGGGCCC
CTCGACCTCCTGCTCCACCT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSNKRIVSGMRPTGKLHLGHFHGVLANWRELQEEYECFFFAADWHSLTTEYDNTAGIRQNTDEMILDWLAFGVDPAKCVI
FRQSRVPQHAELNLILSMITPVSWLERNPTYKEMQENLSTKDLSTFGFLGYPVLMASDIIVYKASKVPVGHDQLPHLEIT
REIARRFNYLYNREVFPEPAALLTETPKVLGLDGRKMSKSYGNAIFLSESAEETRKKVMSMVTDTQRVRRSDPGEPDRCV
AFSLNSLYLPEEKKADIYAGCRSAAIGCVECKKLQAEYLVQTLAPYRARRDELTEKPGLVAEILAEGEARAATEAARTMA
EVRDALNL

Sequences:

>Translated_328_residues
MSNKRIVSGMRPTGKLHLGHFHGVLANWRELQEEYECFFFAADWHSLTTEYDNTAGIRQNTDEMILDWLAFGVDPAKCVI
FRQSRVPQHAELNLILSMITPVSWLERNPTYKEMQENLSTKDLSTFGFLGYPVLMASDIIVYKASKVPVGHDQLPHLEIT
REIARRFNYLYNREVFPEPAALLTETPKVLGLDGRKMSKSYGNAIFLSESAEETRKKVMSMVTDTQRVRRSDPGEPDRCV
AFSLNSLYLPEEKKADIYAGCRSAAIGCVECKKLQAEYLVQTLAPYRARRDELTEKPGLVAEILAEGEARAATEAARTMA
EVRDALNL
>Mature_327_residues
SNKRIVSGMRPTGKLHLGHFHGVLANWRELQEEYECFFFAADWHSLTTEYDNTAGIRQNTDEMILDWLAFGVDPAKCVIF
RQSRVPQHAELNLILSMITPVSWLERNPTYKEMQENLSTKDLSTFGFLGYPVLMASDIIVYKASKVPVGHDQLPHLEITR
EIARRFNYLYNREVFPEPAALLTETPKVLGLDGRKMSKSYGNAIFLSESAEETRKKVMSMVTDTQRVRRSDPGEPDRCVA
FSLNSLYLPEEKKADIYAGCRSAAIGCVECKKLQAEYLVQTLAPYRARRDELTEKPGLVAEILAEGEARAATEAARTMAE
VRDALNL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=328, Percent_Identity=32.6219512195122, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI41352700, Length=184, Percent_Identity=39.6739130434783, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1789786, Length=350, Percent_Identity=31.1428571428571, Blast_Score=152, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71982800, Length=333, Percent_Identity=30.9309309309309, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71982793, Length=333, Percent_Identity=31.2312312312312, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=30.4597701149425, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=32.1321321321321, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37145; Mature: 37014

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKRIVSGMRPTGKLHLGHFHGVLANWRELQEEYECFFFAADWHSLTTEYDNTAGIRQN
CCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCEEEEEECHHHHHCCCCCCCCCCCC
TDEMILDWLAFGVDPAKCVIFRQSRVPQHAELNLILSMITPVSWLERNPTYKEMQENLST
HHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
KDLSTFGFLGYPVLMASDIIVYKASKVPVGHDQLPHLEITREIARRFNYLYNREVFPEPA
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
ALLTETPKVLGLDGRKMSKSYGNAIFLSESAEETRKKVMSMVTDTQRVRRSDPGEPDRCV
HHHHCCCHHCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
AFSLNSLYLPEEKKADIYAGCRSAAIGCVECKKLQAEYLVQTLAPYRARRDELTEKPGLV
EEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AEILAEGEARAATEAARTMAEVRDALNL
HHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNKRIVSGMRPTGKLHLGHFHGVLANWRELQEEYECFFFAADWHSLTTEYDNTAGIRQN
CCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCEEEEEECHHHHHCCCCCCCCCCCC
TDEMILDWLAFGVDPAKCVIFRQSRVPQHAELNLILSMITPVSWLERNPTYKEMQENLST
HHHHHHHHHHHCCCHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCH
KDLSTFGFLGYPVLMASDIIVYKASKVPVGHDQLPHLEITREIARRFNYLYNREVFPEPA
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCH
ALLTETPKVLGLDGRKMSKSYGNAIFLSESAEETRKKVMSMVTDTQRVRRSDPGEPDRCV
HHHHCCCHHCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
AFSLNSLYLPEEKKADIYAGCRSAAIGCVECKKLQAEYLVQTLAPYRARRDELTEKPGLV
EEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AEILAEGEARAATEAARTMAEVRDALNL
HHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]