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The map label for this gene is iscR [H]

Identifier: 78223138

GI number: 78223138

Start: 2156815

End: 2157222

Strand: Reverse

Name: iscR [H]

Synonym: Gmet_1931

Alternate gene names: 78223138

Gene position: 2157222-2156815 (Counterclockwise)

Preceding gene: 78223139

Following gene: 78223137

Centisome position: 53.97

GC content: 58.58

Gene sequence:

>408_bases
ATGATGGAGCTTACACGAAAAGGCGAATACGCAATCAGGGGAATAATTCATCTGGCCCAGTTGCCGCCGGGGAAAGTGGC
GCTCATCAGCGAGATCGCCGAGGCAACCGATGTTCCGCAGACGTTTCTGGCCAAGATACTGCAGAGTTTCGCCAAGATCG
GCATCGTTCAGTCGTTCCGGGGGGCAGGGGGGGGGTTCATGCTTGGTCGTTCCGCCTCCAGGATCACTCTGCGCGAAGTG
GTGGAGGCGGTGGAAGGGCCTATTTTGCCAAATCGCTGCCTGATCGGTTCAGGGACCTGTGAACGGGACAGCACCTGCGG
CGTCCATCCGGTCTGGAGGCAAGTGCAGCAACGGGTCGTGGAGGTTCTCGACGGAGTCACCATTGAAGATCTTGCCACGC
ACAAGTAG

Upstream 100 bases:

>100_bases
GCGAGAAGCAGGGATAAGTAATTTATGTGCGAGAAAATATATTGACAGGTCTGAAAGCTTTAGGTATAAAAAGACTAAAT
TGGTCTTATAGGTGCTATTT

Downstream 100 bases:

>100_bases
ATAACACAAAATTTTTTTGCCCCCATACAGGATAAATTTAGTCCTGTATGGTATAATAATCAGAAAATTGTGTTTATGGT
TACGAAACAAATTGAGGCTT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MMELTRKGEYAIRGIIHLAQLPPGKVALISEIAEATDVPQTFLAKILQSFAKIGIVQSFRGAGGGFMLGRSASRITLREV
VEAVEGPILPNRCLIGSGTCERDSTCGVHPVWRQVQQRVVEVLDGVTIEDLATHK

Sequences:

>Translated_135_residues
MMELTRKGEYAIRGIIHLAQLPPGKVALISEIAEATDVPQTFLAKILQSFAKIGIVQSFRGAGGGFMLGRSASRITLREV
VEAVEGPILPNRCLIGSGTCERDSTCGVHPVWRQVQQRVVEVLDGVTIEDLATHK
>Mature_135_residues
MMELTRKGEYAIRGIIHLAQLPPGKVALISEIAEATDVPQTFLAKILQSFAKIGIVQSFRGAGGGFMLGRSASRITLREV
VEAVEGPILPNRCLIGSGTCERDSTCGVHPVWRQVQQRVVEVLDGVTIEDLATHK

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=9e-15,
Organism=Escherichia coli, GI1790621, Length=130, Percent_Identity=31.5384615384615, Blast_Score=71, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 14622; Mature: 14622

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELTRKGEYAIRGIIHLAQLPPGKVALISEIAEATDVPQTFLAKILQSFAKIGIVQSFR
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GAGGGFMLGRSASRITLREVVEAVEGPILPNRCLIGSGTCERDSTCGVHPVWRQVQQRVV
CCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHH
EVLDGVTIEDLATHK
HHHCCCCHHHHHCCC
>Mature Secondary Structure
MMELTRKGEYAIRGIIHLAQLPPGKVALISEIAEATDVPQTFLAKILQSFAKIGIVQSFR
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GAGGGFMLGRSASRITLREVVEAVEGPILPNRCLIGSGTCERDSTCGVHPVWRQVQQRVV
CCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHH
EVLDGVTIEDLATHK
HHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA