| Definition | Geobacter metallireducens GS-15 chromosome, complete genome. |
|---|---|
| Accession | NC_007517 |
| Length | 3,997,420 |
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The map label for this gene is acnB [H]
Identifier: 78223119
GI number: 78223119
Start: 2132484
End: 2135027
Strand: Reverse
Name: acnB [H]
Synonym: Gmet_1912
Alternate gene names: 78223119
Gene position: 2135027-2132484 (Counterclockwise)
Preceding gene: 78223120
Following gene: 78223118
Centisome position: 53.41
GC content: 60.73
Gene sequence:
>2544_bases ATGATCGAAGCCTATCTCGCCCACGAAGCCGAACGGAAGGCGCAGGGTATTCCGGCGCTGCCCCTCAACCCGGAGCAGAC TGCCGACCTGTGCAACCTGCTGCAAAATCCCCCTGCAGGTAAGGAGGAATTCCTTCTCAATCTGTTGAAAGAGCGCGTCT CCCCCGGCGTCGATCCTGCCGCCAAGGTCAAGGCTGCTTTCCTGGCCGAAATCGTCAAGGGTACCAAGAAGTCACCGCTG GTTTCCAAGGTGGATGCCATCCGCATCCTCGGCACCATGATCGGCGGCTACAACGTGGGTCCCCTGGTTGAGGCCCTCAA GGATGCAGAACTGGCCGAAGAAGCCGCCTGTGCCCTTTCCCGCATGACTCTGGTCTATGATGGCTTCGATCAGGTTGTAG AACTCAGCAAGAGCAATGCCGCCGCCAAGAAGGTACTGGAGTCTTGGGCCAATGCCGAGTGGTTCACCAACCGCCCCGGC GTTCCCGAGACCATCAAGGTCAAGGTTTTCAAGGTTGAAGGCGAGATCAACACCGACGACTTCTCCCCGGCCGGCGACGC CTGGAGCCGTCCCGATATCCCCCTTCACGCCCTGGCCATGGGCAAGACCCGCTTCCCGAACCGCCTCAAAGACATTGCTG ACTGGCGCGCCGCCGGTCACCAAGTGGCCTTCGTGGGTGACGTGGTCGGTACCGGTTCTTCCCGCAAGTCCGCCTGCAAC AGCGTGCTCTGGCACATGGGGCAGGACATCCCCGCCGTTCCCAACAAGAAGACTGCCGGTGTCATCATCGGCGGCGTCAT CGCCCCGATCTTCTTCAATACCGCCCAGGATTCCGGTGCGCTCCCCCTCAAGGCTGATGTCACCAAGATGAACGACGGCG ACGTCATCACCATCAACACCGCCAAAGGCGAGATCTCCAACGATAAGGGCGAGGTCATCTCCACCTTCAAAATCAGCCCC AACACCCTGGCCGACGAGTTCCGCGCCGGTGGCCGGATTCCGCTCATCATCGGCCGCGCTATCACCGAGAAGGCCCGCAA GGCCCTCGGCCTCGGCGATACCGATGTCTTCACCAAGCCGGTGAACCCCGCGCCCAAAGCCGGCCAGGGCTACTCCCTTG CCCAAAAGATGGTCGGCAAGGCCTGCGGCGTGGCCGGTATCCTCCCTGGCACCGCCTGCGAGCCGAAGATGACCACTGTC GGTTCCCAGGACACCACCGGCCCCATGACCGCCGACGAACTCAAGGAACTGGCCTGCCTCAAGTTCCTGTCGCCGATGTT CATGCAGTCCTTCTGCCACACCGCCGCTTATCCGAAGCCGGCCGATGTGAAAATGCACAAAAACCTCCCCGGCTTCATCA TCGAGCGGGGCGGCGTACCCCTCAAGCCGGGTGACGGCGTTATCCACTCCTGGCTGAATCGTCTGCTCCTCCCGGATACC GTCGGTACCGGCGGCGACTCCCACACCCGCTTCCCCATCGGCATCAGCTTCCCGGCCGGTTCCGGACTGGTTGCCTTCGC CGGTGCCATGGGCTTCATGCCGCTTGATATGCCCGAGTCGGTCCTGGTTCGCTTCAAGGGTAAGCTCAACCCCGGCATCA CCCTTCGCGACGCGGTCAACGCCATCCCCTACTGGGCCATCAAGCAGGGCAAACTGACCGTTCCCAAGAAGAACAAGATC AACATCTTCAACGGCCGCATCCTCGAGATGGAAGGGCTTCCCGACCTGACCGTGGAACAGGCCTTCGAGCTGACCGACGC TGCTGCCGAGCGCTCCGCCGCCGCAGGCTGCATCCAGCTCTCCAAGGAGAGCGTGGCCACCTACCTCCGCTCCAACGTAG CCCTCATGAAAAAGATGATTGCTGACGGCTACCAGGATGCCCAGACCCTCCAGAATCGCATCGACGCCGTCAATGAGTGG CTGAAGAACCCGCAGCTCCTCGAAGCCGACAAGAACGCCGTCGAGACCGGCGCCTACGCCGACGTCATCGAGATCGACCT GGCCGAGATCACTGAGCCGATCCTGGCCTGCCCCAATGACCCGGACGACGTGAAGCTCCTCTCCGATGTTGCCGGCACTC CGATCCAGGACGTCTTCCTCGGCTCCTGCATGACCAACATCGGTCACTTCCGTGCTGCCGCCGAGATCTGGCGCGGTCTT AAGTTCAACCCGAGCGTCCGCACCTGGATCTGCCCGCCGACCCGCATGGATCAGAAGCAGCTTAAGGACGAAGCTTACTT CTCGGTATACAGCGCCTTCGGGGCCCGGATCGAAATTGCCGGTTGCTCCCTCTGCATGGGTAACCAAGCCCGCGTTCCCG ATGGTGTCAATATGTTCTCCACTTCAACCCGCAACTTTGACGACCGGATCGGTGATGGCGCTAAAGTATTCCTCGGTTCT GCCGAATTGGGCGCGGTAACTGCAACCTTGGGCAAACTGCCTACTGTTGCTGAGTTTATGGCTGCATACAAAGAGAAGGT TGAACCTAAGAAGGATGTTGTTTACAAGTATCTCCAGTTCGACGAGATGCCTGAGTACAAGTAA
Upstream 100 bases:
>100_bases CAAAAATTGTATACAGTATCCATTTTCTCCCGCCGCACAATCATTTCAACGTCTCGAAATAACGATTGATTCAAGAAGTA AAATCACAGGAGGAATGGAT
Downstream 100 bases:
>100_bases CCTCAACGCATGATACAGAATGCTTGAGGCAGAGATGCTGAAAGCATGACATGAGACCCCCGTTCGGGCTTGCCCGGGCG GGGGTCTTGAATTTTGCGGA
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 847; Mature: 847
Protein sequence:
>847_residues MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPAAKVKAAFLAEIVKGTKKSPL VSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALSRMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPG VPETIKVKVFKVEGEINTDDFSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACN SVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINTAKGEISNDKGEVISTFKISP NTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKPVNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTV GSQDTTGPMTADELKELACLKFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDT VGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVNAIPYWAIKQGKLTVPKKNKI NIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQLSKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEW LKNPQLLEADKNAVETGAYADVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGL KFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFSTSTRNFDDRIGDGAKVFLGS AELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQFDEMPEYK
Sequences:
>Translated_847_residues MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPAAKVKAAFLAEIVKGTKKSPL VSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALSRMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPG VPETIKVKVFKVEGEINTDDFSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACN SVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINTAKGEISNDKGEVISTFKISP NTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKPVNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTV GSQDTTGPMTADELKELACLKFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDT VGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVNAIPYWAIKQGKLTVPKKNKI NIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQLSKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEW LKNPQLLEADKNAVETGAYADVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGL KFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFSTSTRNFDDRIGDGAKVFLGS AELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQFDEMPEYK >Mature_847_residues MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPAAKVKAAFLAEIVKGTKKSPL VSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALSRMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPG VPETIKVKVFKVEGEINTDDFSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACN SVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINTAKGEISNDKGEVISTFKISP NTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKPVNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTV GSQDTTGPMTADELKELACLKFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDT VGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVNAIPYWAIKQGKLTVPKKNKI NIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQLSKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEW LKNPQLLEADKNAVETGAYADVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGL KFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFSTSTRNFDDRIGDGAKVFLGS AELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQFDEMPEYK
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Escherichia coli, GI2367097, Length=858, Percent_Identity=62.3543123543124, Blast_Score=1022, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=366, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=2e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 91142; Mature: 91142
Theoretical pI: Translated: 6.45; Mature: 6.45
Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPA CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH AKVKAAFLAEIVKGTKKSPLVSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALS HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH RMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPGVPETIKVKVFKVEGEINTDD HHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCC FSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACN CCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHH SVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINT HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCEEECCEECCCCCEEEEEC AKGEISNDKGEVISTFKISPNTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKP CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCC VNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTVGSQDTTGPMTADELKELACL CCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHH KFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDT HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCC VGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVN CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHEECCCCCCCEEHHHHHC AIPYWAIKQGKLTVPKKNKINIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQL CCCCEEEECCEEECCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH SKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEWLKNPQLLEADKNAVETGAYA HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCCCH DVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGL HHHEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC KFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFS CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEECCCCCCCCCCCCHHC TSTRNFDDRIGDGAKVFLGSAELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQF CCCCCCHHHCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH DEMPEYK CCCCCCC >Mature Secondary Structure MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPA CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH AKVKAAFLAEIVKGTKKSPLVSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALS HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH RMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPGVPETIKVKVFKVEGEINTDD HHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCC FSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACN CCCCCCCCCCCCCCEEHEECCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHH SVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINT HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCEEECCEECCCCCEEEEEC AKGEISNDKGEVISTFKISPNTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKP CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCC VNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTVGSQDTTGPMTADELKELACL CCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHH KFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDT HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCC VGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVN CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHEECCCCCCCEEHHHHHC AIPYWAIKQGKLTVPKKNKINIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQL CCCCEEEECCEEECCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH SKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEWLKNPQLLEADKNAVETGAYA HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHCCCCH DVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGL HHHEEEHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC KFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFS CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEECCCCCCCCCCCCHHC TSTRNFDDRIGDGAKVFLGSAELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQF CCCCCCHHHCCCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH DEMPEYK CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]