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The map label for this gene is clpX

Identifier: 78223079

GI number: 78223079

Start: 2086865

End: 2088118

Strand: Reverse

Name: clpX

Synonym: Gmet_1872

Alternate gene names: 78223079

Gene position: 2088118-2086865 (Counterclockwise)

Preceding gene: 78223080

Following gene: 78223078

Centisome position: 52.24

GC content: 50.88

Gene sequence:

>1254_bases
GTGAGTAGAAGAAACGACAGCAGCGAAAATCTGACCTGTTCTTTCTGTGGCAAGAGCCAGGATGAGGTGAAGAAGCTCAT
CGCAGGGCCGACGGTCTATATTTGTGATGAATGCATCGAACTCTGCAATGATATTATTGCCGAAGAAAGCAAGCTTGAAG
AGGCCATGGGACCGGACGTAAAGAAACTTCCCAAGCCCCGTGAAATCAAGGATGTTCTTGATGAGTACGTCATCGGTCAG
GACCGGGCCAAGAAAATCCTTGCCGTTGCTGTCTACAATCACTACAAGCGTATCGAGTCCATGGGTAAGCCAAGCGACGT
GGAGATGCAGAAAAGCAACATACTCCTCTTGGGTCCCACCGGTTCAGGCAAGACTCTTCTTGCCCAGACCCTTGCGCGGA
TTCTCAGGGTTCCGTTCGCGATGGCTGACGCCACCAATCTTACGGAAGCCGGGTATGTTGGTGAGGATGTTGAGAATATT
ATCCTCAACCTCCTGCAGGCTGCCGATTACGATGTGGAGCGTGCCCAGAAGGGCATTATCTATATTGACGAAATAGACAA
GATTGCCCGCAAATCCGATTCTCCGTCCATAACCCGCGATGTCTCGGGGGAAGGGGTTCAGCAGGCGTTGCTCAAAATAA
TTGAAGGCACCGTTGCCAGCGTGCCTCCAAAGGGTGGCCGAAAGCATCCCCAGCAGGAATTTCTCAAGGTTGATACCTCA
AACATTCTGTTCATCTGCGGTGGAGCCTTTGCCGGCCTCGATAACATCATTCAGCAGCGTATTGGTGTCAAGACCCTTGG
CTTTGGTGCCGACGTCAAGAGCAAGGTGGAGAAGAAGGCCGGTGAACTCCTTACTGACGTTACCCCGGAGGATCTTCTCA
AGTTCGGGTTTATCCCAGAGTTTATTGGGCGTCTTCCGGTGCTTGCCACGCTTCACGAACTGGACGAGGCAGCAATGGTT
CAGATTCTCAAAGAACCGAAGAGTGCTCTCGTCAAGCAGTACCAGAAACTCTTCGAGATGGAACACGTGAAGCTCAAATT
TACCGATGGTTCACTCGTCGCTATAGCGCGTGAAGCTCTGAAGCGCAAGACTGGTGCCCGGGGGCTTCGATCCATTCTGG
AAAATGCCATGCTCGATATCATGTACGAGATTCCTTCTCAAACCATGGTAAAGGAAGTAGTCATAAGCGAAGATGTAATC
TATAACCGGGAAAAACCGATCATAGTCTACGAAAGTGTGGCGGAATCCGCCTGA

Upstream 100 bases:

>100_bases
CTGACACCGAGCGTGATTATTTTATGTCTGGTGAAGAAGCAAAATCGTATGGTATTATTGACGCAATTATAGCGCGTAAA
CCCACCAGCGGAGGTTCTCG

Downstream 100 bases:

>100_bases
TCTGAGGAACTAGATGCACGATAATCAAGGTAGTCAACCGCTCAAGAGAGGGGATCTGGAAAGATTCCCTCTTTTACCAT
TAAGAGATATTGTTGTGTTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSRRNDSSENLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQ
DRAKKILAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILRVPFAMADATNLTEAGYVGEDVENI
ILNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTS
NILFICGGAFAGLDNIIQQRIGVKTLGFGADVKSKVEKKAGELLTDVTPEDLLKFGFIPEFIGRLPVLATLHELDEAAMV
QILKEPKSALVKQYQKLFEMEHVKLKFTDGSLVAIAREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVISEDVI
YNREKPIIVYESVAESA

Sequences:

>Translated_417_residues
MSRRNDSSENLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQ
DRAKKILAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILRVPFAMADATNLTEAGYVGEDVENI
ILNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTS
NILFICGGAFAGLDNIIQQRIGVKTLGFGADVKSKVEKKAGELLTDVTPEDLLKFGFIPEFIGRLPVLATLHELDEAAMV
QILKEPKSALVKQYQKLFEMEHVKLKFTDGSLVAIAREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVISEDVI
YNREKPIIVYESVAESA
>Mature_416_residues
SRRNDSSENLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDVKKLPKPREIKDVLDEYVIGQD
RAKKILAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPTGSGKTLLAQTLARILRVPFAMADATNLTEAGYVGEDVENII
LNLLQAADYDVERAQKGIIYIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTSN
ILFICGGAFAGLDNIIQQRIGVKTLGFGADVKSKVEKKAGELLTDVTPEDLLKFGFIPEFIGRLPVLATLHELDEAAMVQ
ILKEPKSALVKQYQKLFEMEHVKLKFTDGSLVAIAREALKRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVISEDVIY
NREKPIIVYESVAESA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=337, Percent_Identity=49.8516320474777, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786642, Length=410, Percent_Identity=68.5365853658537, Blast_Score=568, Evalue=1e-163,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=44.6601941747573, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=46.0365853658537, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=328, Percent_Identity=46.0365853658537, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=428, Percent_Identity=37.8504672897196, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=39.922480620155, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=413, Percent_Identity=40.9200968523002, Blast_Score=268, Evalue=8e-73,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=47.0219435736677, Blast_Score=294, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=47.0219435736677, Blast_Score=294, Evalue=8e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_GEOMG (Q39UH3)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384826.1
- ProteinModelPortal:   Q39UH3
- STRING:   Q39UH3
- GeneID:   3740270
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1872
- NMPDR:   fig|269799.3.peg.2135
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q39UH3
- ProtClustDB:   PRK05342
- BioCyc:   GMET269799:GMET_1872-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46056; Mature: 45925

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRNDSSENLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDV
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKLPKPREIKDVLDEYVIGQDRAKKILAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCC
GSGKTLLAQTLARILRVPFAMADATNLTEAGYVGEDVENIILNLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTS
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
NILFICGGAFAGLDNIIQQRIGVKTLGFGADVKSKVEKKAGELLTDVTPEDLLKFGFIPE
CEEEEECCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHH
FIGRLPVLATLHELDEAAMVQILKEPKSALVKQYQKLFEMEHVKLKFTDGSLVAIAREAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHH
KRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVISEDVIYNREKPIIVYESVAESA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
SRRNDSSENLTCSFCGKSQDEVKKLIAGPTVYICDECIELCNDIIAEESKLEEAMGPDV
CCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKLPKPREIKDVLDEYVIGQDRAKKILAVAVYNHYKRIESMGKPSDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCC
GSGKTLLAQTLARILRVPFAMADATNLTEAGYVGEDVENIILNLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSDSPSITRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQEFLKVDTS
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
NILFICGGAFAGLDNIIQQRIGVKTLGFGADVKSKVEKKAGELLTDVTPEDLLKFGFIPE
CEEEEECCHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHH
FIGRLPVLATLHELDEAAMVQILKEPKSALVKQYQKLFEMEHVKLKFTDGSLVAIAREAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHH
KRKTGARGLRSILENAMLDIMYEIPSQTMVKEVVISEDVIYNREKPIIVYESVAESA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA