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The map label for this gene is ftsX [H]

Identifier: 78223062

GI number: 78223062

Start: 2068558

End: 2069508

Strand: Reverse

Name: ftsX [H]

Synonym: Gmet_1855

Alternate gene names: 78223062

Gene position: 2069508-2068558 (Counterclockwise)

Preceding gene: 78223063

Following gene: 78223061

Centisome position: 51.77

GC content: 51.84

Gene sequence:

>951_bases
ATGTCCCGAAATAAGCCGTCCATTCGTCCCGCCATGTCCAGTGACGGGGTAGGGGGGAGGATCCGCTACTTCTTTGCCCG
GGCACTCCTCAATATTCGTCAGAACGTTCTGGTGAACGTTCTCGCCATCGGTACCATAACCCTGGCGCTTCTTATCGTTT
CGCTGTTCCTCCTCATTTTCGTGAATCTGGAGTCTACGGCCGATGAGTGGAGTGGGAAGATTCAGGTGACCGCGTATTTC
AATACTGAGCCAACCCCTCAGGAACTTTCTGCTATCATGACGAGGGTGAAGGCCATTGATGGGACTGATAAGGTCGGGTA
CGTCAGCAAACAGGAAGCCATGAAGCGTTTTCGCGAACGTCTGAAGGGCCAGGAAACTCTTCTCGAAGGGGTTCCGGCGG
ACGTGCTTCCTTCTTCCATCGAGATAACTCTGAAGCGTAATAGTCGTGAAGATGCCGCTATGGAGGCTTATGTTGGCAGG
CTCAAAAAAGTTCCCGGCATAGCGGAGGTCCAGTATGGCGAAGAATGGGTCAGGCGCTTCAATACGTTCATGAACTTCCT
TCGCTTTGTGGGAGCGCTCCTTGGAGGATTCCTCCTGATGGCAGTGCTCTTTATTGTGTCAAACACCATAAAATTGACAA
TCTACGCCAGAAAAGAGGAGATTGAGGTGATGGAGCTTGTGGGGGCCACCCGATTTTTCATCAAGGCTCCTTTCCTCATT
GAGGGAATCATCCAGGGCGCTGCCGGAGCAGTTCTGTCACTTCTCATTCTTGTGGCTGCTTTTTTCGGTTTTCTCCACAG
CGCGACGAATTTCGTCAACTTCTCCTCGTCGGTATCGGGGCTTTCGTTCCTTCCGCCATTGTATATTGCCGGAATTCTTG
CCGGAGGAGTGGTCCTCGGGTTCCTTGGTAGCCTCACTTCCCTGAAACGATTCATCAATAACCCGCAATGA

Upstream 100 bases:

>100_bases
GGTACCACGGTGGTGGTGGCGACCCACGACCGCCGGGTGATCGAGAACAGCCATAGGCGCGTTATCGTGCTCGATAGGGG
CCGCGTTGCGGAGGATACCG

Downstream 100 bases:

>100_bases
GATGGCTACAGTCCATAACCGCTTTGCTGGTGGTGCTCCTTACGGCGGCTGCAGCCGATGCCGATGTGCGTGACCAGTTG
CAGGGGGTCAAGAAGGAAAT

Product: cell division protein FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSRNKPSIRPAMSSDGVGGRIRYFFARALLNIRQNVLVNVLAIGTITLALLIVSLFLLIFVNLESTADEWSGKIQVTAYF
NTEPTPQELSAIMTRVKAIDGTDKVGYVSKQEAMKRFRERLKGQETLLEGVPADVLPSSIEITLKRNSREDAAMEAYVGR
LKKVPGIAEVQYGEEWVRRFNTFMNFLRFVGALLGGFLLMAVLFIVSNTIKLTIYARKEEIEVMELVGATRFFIKAPFLI
EGIIQGAAGAVLSLLILVAAFFGFLHSATNFVNFSSSVSGLSFLPPLYIAGILAGGVVLGFLGSLTSLKRFINNPQ

Sequences:

>Translated_316_residues
MSRNKPSIRPAMSSDGVGGRIRYFFARALLNIRQNVLVNVLAIGTITLALLIVSLFLLIFVNLESTADEWSGKIQVTAYF
NTEPTPQELSAIMTRVKAIDGTDKVGYVSKQEAMKRFRERLKGQETLLEGVPADVLPSSIEITLKRNSREDAAMEAYVGR
LKKVPGIAEVQYGEEWVRRFNTFMNFLRFVGALLGGFLLMAVLFIVSNTIKLTIYARKEEIEVMELVGATRFFIKAPFLI
EGIIQGAAGAVLSLLILVAAFFGFLHSATNFVNFSSSVSGLSFLPPLYIAGILAGGVVLGFLGSLTSLKRFINNPQ
>Mature_315_residues
SRNKPSIRPAMSSDGVGGRIRYFFARALLNIRQNVLVNVLAIGTITLALLIVSLFLLIFVNLESTADEWSGKIQVTAYFN
TEPTPQELSAIMTRVKAIDGTDKVGYVSKQEAMKRFRERLKGQETLLEGVPADVLPSSIEITLKRNSREDAAMEAYVGRL
KKVPGIAEVQYGEEWVRRFNTFMNFLRFVGALLGGFLLMAVLFIVSNTIKLTIYARKEEIEVMELVGATRFFIKAPFLIE
GIIQGAAGAVLSLLILVAAFFGFLHSATNFVNFSSSVSGLSFLPPLYIAGILAGGVVLGFLGSLTSLKRFINNPQ

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=251, Percent_Identity=26.6932270916335, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 34740; Mature: 34609

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNKPSIRPAMSSDGVGGRIRYFFARALLNIRQNVLVNVLAIGTITLALLIVSLFLLIF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNLESTADEWSGKIQVTAYFNTEPTPQELSAIMTRVKAIDGTDKVGYVSKQEAMKRFRER
HCCCCCHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LKGQETLLEGVPADVLPSSIEITLKRNSREDAAMEAYVGRLKKVPGIAEVQYGEEWVRRF
HCHHHHHHHCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NTFMNFLRFVGALLGGFLLMAVLFIVSNTIKLTIYARKEEIEVMELVGATRFFIKAPFLI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHCHHHH
EGIIQGAAGAVLSLLILVAAFFGFLHSATNFVNFSSSVSGLSFLPPLYIAGILAGGVVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLGSLTSLKRFINNPQ
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRNKPSIRPAMSSDGVGGRIRYFFARALLNIRQNVLVNVLAIGTITLALLIVSLFLLIF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNLESTADEWSGKIQVTAYFNTEPTPQELSAIMTRVKAIDGTDKVGYVSKQEAMKRFRER
HCCCCCHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LKGQETLLEGVPADVLPSSIEITLKRNSREDAAMEAYVGRLKKVPGIAEVQYGEEWVRRF
HCHHHHHHHCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
NTFMNFLRFVGALLGGFLLMAVLFIVSNTIKLTIYARKEEIEVMELVGATRFFIKAPFLI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHCHHHH
EGIIQGAAGAVLSLLILVAAFFGFLHSATNFVNFSSSVSGLSFLPPLYIAGILAGGVVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLGSLTSLKRFINNPQ
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]