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The map label for this gene is kamA [H]

Identifier: 78223047

GI number: 78223047

Start: 2053261

End: 2054295

Strand: Reverse

Name: kamA [H]

Synonym: Gmet_1840

Alternate gene names: 78223047

Gene position: 2054295-2053261 (Counterclockwise)

Preceding gene: 78223048

Following gene: 78223043

Centisome position: 51.39

GC content: 60.97

Gene sequence:

>1035_bases
ATGGAAACGTGGCGAAAGGCCATCGCCGACAGCATAACCACCCCCGAGGAGCTTGCGGAGCTTCTGGATATTGATCCCGA
ACCCCTTGCGCCGCTTGTCCGGCGTTATCCACTGCGGATTACGCGGCGCTATCTGGGGCTCATCGGGAAGCCGGGCGATG
CGATCTGGCGCCAATGCGTCCCTGACCCATGTGAGCTCGATGACGATCAGCTTTCCGATCCCCTTGACGAGGAACGGCTT
TCGCCTGTTCCCGGCGTTATTCACCGCTATCCCGACCGGGTCGTCTGGCTCGTTTCCAACGAGTGTGCCGTCTACTGCCG
TTTTTGCATGCGGAAGCGCCGGGTGGGATGCCCGCTGGCGGGGAGCAACGGGCGTTCCGGGGATGATGCGGTCAGGTACA
TCGCGGCGACACCGGCCATACGGGACGTGATCCTGTCCGGGGGAGATCCGCTGCTTCTGGATGATGAGCGACTCGAAGCG
ATCCTGGCACGCCTGCGCGCCATTCCCCACGTGGAGATGATTCGGATCGGCACCCGTACCCCCGTAACCCTGCCGGAAAG
GATTACGGCACGGCTCTGTCGAATGCTCAAACGTTACCACCCCCTCTACGTCAATACCCATTTCAACCATCCGCGAGAGA
TCACTCCCGAGGCGACCAAGGCCTGTGCCCGTCTGGCAGACACCGGCATTCCCCTGGGCAACCAGACGGTGCTCCTTGCC
GGCGTCAATGATGAGCCGGCGATTATGACGCTTCTCATGCAGCGTCTCCTCGCCATCAGGGTAAGGCCGTACTACATCCA
TCAGATGGACCTGGTTAGGGGAACCGGTCACTTCCGTACCAAGGTGACAACGGGGCTCGATATCATAGGGGCTTTGCGGG
GGCATACCTCAGGGATGGCGACACCCTACTTTGTCATTGATGCGGCGGGTGGAAAGGGGAAGATACCGCTTCTCCCCGAT
GCCGTGGAGCGGCGGGGTGATACGTGGCTGTTACGGAACTACCGGGGAGAGATTGTCGAATACCAGGATCGGTGA

Upstream 100 bases:

>100_bases
CGGCGCACTGCAGGTCTGAAAACCAGCAGACGAGTTGCTTCTGTGAGCGAAGGCGGGGTTCCTCCCCGCCTTTGTCCGTT
TGTGGAAGGAGAGCGTAAAG

Downstream 100 bases:

>100_bases
GGGGGAGGGGAGTTACAGTTCCTCAGGGGGAAACGCCACCACGTCGTCAATGGTGTCGGCATCAAGCAACACCATCACGA
GCCGGTCGATGCCGAGGGCG

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
METWRKAIADSITTPEELAELLDIDPEPLAPLVRRYPLRITRRYLGLIGKPGDAIWRQCVPDPCELDDDQLSDPLDEERL
SPVPGVIHRYPDRVVWLVSNECAVYCRFCMRKRRVGCPLAGSNGRSGDDAVRYIAATPAIRDVILSGGDPLLLDDERLEA
ILARLRAIPHVEMIRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITPEATKACARLADTGIPLGNQTVLLA
GVNDEPAIMTLLMQRLLAIRVRPYYIHQMDLVRGTGHFRTKVTTGLDIIGALRGHTSGMATPYFVIDAAGGKGKIPLLPD
AVERRGDTWLLRNYRGEIVEYQDR

Sequences:

>Translated_344_residues
METWRKAIADSITTPEELAELLDIDPEPLAPLVRRYPLRITRRYLGLIGKPGDAIWRQCVPDPCELDDDQLSDPLDEERL
SPVPGVIHRYPDRVVWLVSNECAVYCRFCMRKRRVGCPLAGSNGRSGDDAVRYIAATPAIRDVILSGGDPLLLDDERLEA
ILARLRAIPHVEMIRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITPEATKACARLADTGIPLGNQTVLLA
GVNDEPAIMTLLMQRLLAIRVRPYYIHQMDLVRGTGHFRTKVTTGLDIIGALRGHTSGMATPYFVIDAAGGKGKIPLLPD
AVERRGDTWLLRNYRGEIVEYQDR
>Mature_344_residues
METWRKAIADSITTPEELAELLDIDPEPLAPLVRRYPLRITRRYLGLIGKPGDAIWRQCVPDPCELDDDQLSDPLDEERL
SPVPGVIHRYPDRVVWLVSNECAVYCRFCMRKRRVGCPLAGSNGRSGDDAVRYIAATPAIRDVILSGGDPLLLDDERLEA
ILARLRAIPHVEMIRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITPEATKACARLADTGIPLGNQTVLLA
GVNDEPAIMTLLMQRLLAIRVRPYYIHQMDLVRGTGHFRTKVTTGLDIIGALRGHTSGMATPYFVIDAAGGKGKIPLLPD
AVERRGDTWLLRNYRGEIVEYQDR

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=328, Percent_Identity=36.280487804878, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 38721; Mature: 38721

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METWRKAIADSITTPEELAELLDIDPEPLAPLVRRYPLRITRRYLGLIGKPGDAIWRQCV
CCHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
PDPCELDDDQLSDPLDEERLSPVPGVIHRYPDRVVWLVSNECAVYCRFCMRKRRVGCPLA
CCCCCCCHHHCCCCCCHHHCCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
GSNGRSGDDAVRYIAATPAIRDVILSGGDPLLLDDERLEAILARLRAIPHVEMIRIGTRT
CCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCC
PVTLPERITARLCRMLKRYHPLYVNTHFNHPREITPEATKACARLADTGIPLGNQTVLLA
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEE
GVNDEPAIMTLLMQRLLAIRVRPYYIHQMDLVRGTGHFRTKVTTGLDIIGALRGHTSGMA
ECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCC
TPYFVIDAAGGKGKIPLLPDAVERRGDTWLLRNYRGEIVEYQDR
CCEEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCCCEEEECCC
>Mature Secondary Structure
METWRKAIADSITTPEELAELLDIDPEPLAPLVRRYPLRITRRYLGLIGKPGDAIWRQCV
CCHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
PDPCELDDDQLSDPLDEERLSPVPGVIHRYPDRVVWLVSNECAVYCRFCMRKRRVGCPLA
CCCCCCCHHHCCCCCCHHHCCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
GSNGRSGDDAVRYIAATPAIRDVILSGGDPLLLDDERLEAILARLRAIPHVEMIRIGTRT
CCCCCCCHHHHHHHHCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCC
PVTLPERITARLCRMLKRYHPLYVNTHFNHPREITPEATKACARLADTGIPLGNQTVLLA
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEE
GVNDEPAIMTLLMQRLLAIRVRPYYIHQMDLVRGTGHFRTKVTTGLDIIGALRGHTSGMA
ECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCC
TPYFVIDAAGGKGKIPLLPDAVERRGDTWLLRNYRGEIVEYQDR
CCEEEEECCCCCCCCCCCCHHHHHCCCEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]