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The map label for this gene is paaK [H]

Identifier: 78223007

GI number: 78223007

Start: 2014298

End: 2015650

Strand: Reverse

Name: paaK [H]

Synonym: Gmet_1800

Alternate gene names: 78223007

Gene position: 2015650-2014298 (Counterclockwise)

Preceding gene: 78223008

Following gene: 78222998

Centisome position: 50.42

GC content: 64.23

Gene sequence:

>1353_bases
ATGAATAGGACGCCGCTGGAGGGGTGGATACGGGACAAGTTGCTTCTGCCCGGCACGCAGGCACTGACGCGGAGCGACCT
CGAGGCCTATCAGGTGCGAAAACTGCGGGAGGTGGTCGCCTATGCCCGGACGAAGAGCCCCTTCTACCGGAACCTTCTTG
CCGAAATCGACGGTCGGGACGTGAAGGATCTGCAGGCATTCAGCCGCCTCCCCTTCACGACGCCGGACGATGTGCGAACC
CAGGGGATGCGGATGCTCTGCGCCTCCCAGGACGAAATCGAACGGGTGGTCACCCTGCAAACCTCAGGGACCAGCGGCGA
GGCAAAGCGGATATTTTTCACGGCAGAAGACCTGGAGCTGACGGTCGATTTTTTCCATCACGGCATGGCGACCATGGTCG
CTGCCGGGGCAACCGTCATCATCTTTCTGCCCGGCGAACGACCCGACAGCGTTGGTGATCTGCTGGCTCGGGGATTGGCA
CGGCTGGGGGTGAGGCCGGTCGCCTTTGGACCGGTACGGGACCCGATAGCGGCACGGGCGGAGATTCTGCGCCACCCTTC
CCCTTGCCTGGTGGGGATACCGACCCAGATTCTTTCTCTGGCCCGTGGTGAGGGTGGCGAGGCGATTCCACGGGGCTGGG
TGGAGAGCGTCCTTCTTTCCACGGACTACGTGCCCACGGCGATCGTGGAGGAACTGAAGCAGCACTGGGGCTGCCGGGTC
TTCACCCACTACGGCATGACGGAAACCGGGCTGGGGGGAGGCGTGGAGTGTGAGGCAAGGGACGGCTACCATCTGCGCGA
GGCCGACCTGTACACGGAAATCGTCGACCCGGCCACAGGCCGGCCGGTAGCCGATGGCGAGTTCGGGGAAGTGATCTTCA
CGACCCTCACCCGAAGCGGGATGCCGCTCGTGAGGTACCGGACCGGGGATATGGCGAGGATGATGCCGGAATCCTGCCCC
TGCGGCACGGTGCTGAAACGTCTCGGGCGGGTGCAGGGACGAATCGGGGCGACCGTGAGGCTCAGGGATGGGGCAAGCAT
CGCCATGGCAACTCTGGACGAGGCGTTGCTTCCGATTCCCGGACTGCTGAACTTTACGGCCGAAATCGCCGATAACGGCG
GCCGGGATCAACTCAACCTCTGTCTCCAGGCATGCGAGGGGCAGGAAGAACAGGTCGCCAGAGGGGCCGTTGCCGCCCTT
GTGCGCGCCGAATCAAGCGATCCCCTGTTCCGGCAGGGGGGGCTGACGCTGGGGAGCATCACCTTCGACAGGGCCGGCTG
GTTCACGACCGGCACCGGGAAACGGCAGATCAGGGATGTCCGGCAGGAGAACCAAGGTGCCGTAAGTGCATAA

Upstream 100 bases:

>100_bases
ATGGAGAAACTCCAGTCGATACTGGCGACCGTGGGCGGTACAGGTCAATGACCACTCCGTTACCCCCTGTGAAACAAGCA
TGGAAGAAAGGGGTGCCGCG

Downstream 100 bases:

>100_bases
ATTCCTTCTGCAGGGTAATCGGCACGCGGTTGGGCACTCCCCGAAAGGTTGATCCGCTATCCTTTCTGATGTCGCTGAAC
AATCCGACTTTGCCGATAAT

Product: coenzyme F390 synthetase-like

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNRTPLEGWIRDKLLLPGTQALTRSDLEAYQVRKLREVVAYARTKSPFYRNLLAEIDGRDVKDLQAFSRLPFTTPDDVRT
QGMRMLCASQDEIERVVTLQTSGTSGEAKRIFFTAEDLELTVDFFHHGMATMVAAGATVIIFLPGERPDSVGDLLARGLA
RLGVRPVAFGPVRDPIAARAEILRHPSPCLVGIPTQILSLARGEGGEAIPRGWVESVLLSTDYVPTAIVEELKQHWGCRV
FTHYGMTETGLGGGVECEARDGYHLREADLYTEIVDPATGRPVADGEFGEVIFTTLTRSGMPLVRYRTGDMARMMPESCP
CGTVLKRLGRVQGRIGATVRLRDGASIAMATLDEALLPIPGLLNFTAEIADNGGRDQLNLCLQACEGQEEQVARGAVAAL
VRAESSDPLFRQGGLTLGSITFDRAGWFTTGTGKRQIRDVRQENQGAVSA

Sequences:

>Translated_450_residues
MNRTPLEGWIRDKLLLPGTQALTRSDLEAYQVRKLREVVAYARTKSPFYRNLLAEIDGRDVKDLQAFSRLPFTTPDDVRT
QGMRMLCASQDEIERVVTLQTSGTSGEAKRIFFTAEDLELTVDFFHHGMATMVAAGATVIIFLPGERPDSVGDLLARGLA
RLGVRPVAFGPVRDPIAARAEILRHPSPCLVGIPTQILSLARGEGGEAIPRGWVESVLLSTDYVPTAIVEELKQHWGCRV
FTHYGMTETGLGGGVECEARDGYHLREADLYTEIVDPATGRPVADGEFGEVIFTTLTRSGMPLVRYRTGDMARMMPESCP
CGTVLKRLGRVQGRIGATVRLRDGASIAMATLDEALLPIPGLLNFTAEIADNGGRDQLNLCLQACEGQEEQVARGAVAAL
VRAESSDPLFRQGGLTLGSITFDRAGWFTTGTGKRQIRDVRQENQGAVSA
>Mature_450_residues
MNRTPLEGWIRDKLLLPGTQALTRSDLEAYQVRKLREVVAYARTKSPFYRNLLAEIDGRDVKDLQAFSRLPFTTPDDVRT
QGMRMLCASQDEIERVVTLQTSGTSGEAKRIFFTAEDLELTVDFFHHGMATMVAAGATVIIFLPGERPDSVGDLLARGLA
RLGVRPVAFGPVRDPIAARAEILRHPSPCLVGIPTQILSLARGEGGEAIPRGWVESVLLSTDYVPTAIVEELKQHWGCRV
FTHYGMTETGLGGGVECEARDGYHLREADLYTEIVDPATGRPVADGEFGEVIFTTLTRSGMPLVRYRTGDMARMMPESCP
CGTVLKRLGRVQGRIGATVRLRDGASIAMATLDEALLPIPGLLNFTAEIADNGGRDQLNLCLQACEGQEEQVARGAVAAL
VRAESSDPLFRQGGLTLGSITFDRAGWFTTGTGKRQIRDVRQENQGAVSA

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=374, Percent_Identity=27.0053475935829, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49045; Mature: 49045

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTPLEGWIRDKLLLPGTQALTRSDLEAYQVRKLREVVAYARTKSPFYRNLLAEIDGRD
CCCCCCCHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
VKDLQAFSRLPFTTPDDVRTQGMRMLCASQDEIERVVTLQTSGTSGEAKRIFFTAEDLEL
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCEEEEEEECCCCCCCEEEEEEECCCEE
TVDFFHHGMATMVAAGATVIIFLPGERPDSVGDLLARGLARLGVRPVAFGPVRDPIAARA
EHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
EILRHPSPCLVGIPTQILSLARGEGGEAIPRGWVESVLLSTDYVPTAIVEELKQHWGCRV
HHHHCCCCCEEECHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEE
FTHYGMTETGLGGGVECEARDGYHLREADLYTEIVDPATGRPVADGEFGEVIFTTLTRSG
EEECCCCCCCCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
MPLVRYRTGDMARMMPESCPCGTVLKRLGRVQGRIGATVRLRDGASIAMATLDEALLPIP
CCEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCC
GLLNFTAEIADNGGRDQLNLCLQACEGQEEQVARGAVAALVRAESSDPLFRQGGLTLGSI
CHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEE
TFDRAGWFTTGTGKRQIRDVRQENQGAVSA
EECCCCCEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRTPLEGWIRDKLLLPGTQALTRSDLEAYQVRKLREVVAYARTKSPFYRNLLAEIDGRD
CCCCCCCHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
VKDLQAFSRLPFTTPDDVRTQGMRMLCASQDEIERVVTLQTSGTSGEAKRIFFTAEDLEL
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHCEEEEEEECCCCCCCEEEEEEECCCEE
TVDFFHHGMATMVAAGATVIIFLPGERPDSVGDLLARGLARLGVRPVAFGPVRDPIAARA
EHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
EILRHPSPCLVGIPTQILSLARGEGGEAIPRGWVESVLLSTDYVPTAIVEELKQHWGCRV
HHHHCCCCCEEECHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEE
FTHYGMTETGLGGGVECEARDGYHLREADLYTEIVDPATGRPVADGEFGEVIFTTLTRSG
EEECCCCCCCCCCCEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
MPLVRYRTGDMARMMPESCPCGTVLKRLGRVQGRIGATVRLRDGASIAMATLDEALLPIP
CCEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCC
GLLNFTAEIADNGGRDQLNLCLQACEGQEEQVARGAVAALVRAESSDPLFRQGGLTLGSI
CHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEE
TFDRAGWFTTGTGKRQIRDVRQENQGAVSA
EECCCCCEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]