BacMap

Definition	Geobacter metallireducens GS-15 chromosome, complete genome.
Accession	NC_007517
Length	3,997,420

Click here to switch to the map view.

The map label for this gene is crt [H]

Identifier: 78222925

GI number: 78222925

Start: 1929189

End: 1929971

Strand: Reverse

Name: crt [H]

Synonym: Gmet_1716

Alternate gene names: 78222925

Gene position: 1929971-1929189 (Counterclockwise)

Preceding gene: 78222926

Following gene: 78222924

Centisome position: 48.28

GC content: 62.96

Gene sequence:

>783_bases
ATGGAATTCAAGAATCTGCTCATCGAAACCGCTGACGGCGTCGCCACCCTCACCGTCAACCGTCCCCAGGCCCTCAATGC
CCTGAACAGCGAGGTGCTGACCGAGCTGGCCTCCGCCTTCTACCAACTGGAGTACGATCCGGCGGTTCGGGTGGTGGTCC
TCACCGGCGCCGGCGAGAAGGCCTTCGTGGCCGGGGCCGACATCAAAGAGATGGCGGCCATGTCCTCCTTCGAAGGACAC
CAGTTCGCCCTGAAGGGGCAGCACTGCATGATGGCCATGGAGAAGATGAAGACCCCGGTCATCGCCGCGGTGAACGGCTT
CGCCCTGGGGGGCGGGCTGGAACTGGCCCTGGGGTGCGACTTCATCTACGCCTCGGAGAAGGCGAAGCTCGGTTTCCCCG
AGGTGACCCTCGGCATTATCCCCGGCTTCGGCGGCACCCAGAACCTGGCCCGCCTTATCGGGAAGAACCGGGCTAACGAA
CTGATCTTTACCGGCCGGATGATCGCGGCCGACAAGGCCCAGGCCTGGGGGATCGTCAACGAGGTGTTCGCTCCGGAGGA
GCTTCTGGTCAAAGCAAAAGAGACAGCGGCCGCCATCGCCGGCGTCGGCCCCCTGGGGGTTACCTACGCCAAGAATGCCA
TTGCCAACGGCCTGAACATGGGAAAGGAAGACGGCTTCCGCTACGAGGCCTCCCTCTTCGGGGTGCTCTTCGGCACCGCC
GACCAGAAGGAAGGGATGGGGGCCTTTGTGGAAAAGCGGAAAGCAGTATTTACGGGGAAATAA

Upstream 100 bases:

>100_bases
CCGCAGTACGTATAGGGATTTTGGTTATTAGACTTGAAAGGATCTTACGGTTTTGTCTCTCTCTGTGATCTCTGTGCCCT
CTGTGGCTAAAGGAGCCTTT

Downstream 100 bases:

>100_bases
TTTCACAATCAACCATAGGGAGGTTGTCATGAACTTCGAACTGAGCCAGGACCACAAGGTATTGCAGGACGCCGTGCGTG
ACTTCGTGGAGAAGGAGGTA

Product: short chain enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEFKNLLIETADGVATLTVNRPQALNALNSEVLTELASAFYQLEYDPAVRVVVLTGAGEKAFVAGADIKEMAAMSSFEGH
QFALKGQHCMMAMEKMKTPVIAAVNGFALGGGLELALGCDFIYASEKAKLGFPEVTLGIIPGFGGTQNLARLIGKNRANE
LIFTGRMIAADKAQAWGIVNEVFAPEELLVKAKETAAAIAGVGPLGVTYAKNAIANGLNMGKEDGFRYEASLFGVLFGTA
DQKEGMGAFVEKRKAVFTGK

Sequences:

>Translated_260_residues
MEFKNLLIETADGVATLTVNRPQALNALNSEVLTELASAFYQLEYDPAVRVVVLTGAGEKAFVAGADIKEMAAMSSFEGH
QFALKGQHCMMAMEKMKTPVIAAVNGFALGGGLELALGCDFIYASEKAKLGFPEVTLGIIPGFGGTQNLARLIGKNRANE
LIFTGRMIAADKAQAWGIVNEVFAPEELLVKAKETAAAIAGVGPLGVTYAKNAIANGLNMGKEDGFRYEASLFGVLFGTA
DQKEGMGAFVEKRKAVFTGK
>Mature_260_residues
MEFKNLLIETADGVATLTVNRPQALNALNSEVLTELASAFYQLEYDPAVRVVVLTGAGEKAFVAGADIKEMAAMSSFEGH
QFALKGQHCMMAMEKMKTPVIAAVNGFALGGGLELALGCDFIYASEKAKLGFPEVTLGIIPGFGGTQNLARLIGKNRANE
LIFTGRMIAADKAQAWGIVNEVFAPEELLVKAKETAAAIAGVGPLGVTYAKNAIANGLNMGKEDGFRYEASLFGVLFGTA
DQKEGMGAFVEKRKAVFTGK

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=45.9349593495935, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=36.8217054263566, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=36.9318181818182, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI68989263, Length=162, Percent_Identity=40.1234567901235, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=30.0751879699248, Blast_Score=110, Evalue=9e-25,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=32.4110671936759, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=26.0536398467433, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=26.0536398467433, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI221307494, Length=260, Percent_Identity=26.1538461538462, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=27.6, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI25453481, Length=260, Percent_Identity=24.6153846153846, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI51538573, Length=260, Percent_Identity=24.6153846153846, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI157694516, Length=231, Percent_Identity=25.5411255411255, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI213417737, Length=231, Percent_Identity=25.5411255411255, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4757966, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI51538581, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI116235487, Length=209, Percent_Identity=27.7511961722488, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4757968, Length=262, Percent_Identity=23.6641221374046, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI49355787, Length=262, Percent_Identity=23.6641221374046, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI37594471, Length=158, Percent_Identity=30.379746835443, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI37594469, Length=160, Percent_Identity=30, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI261878539, Length=76, Percent_Identity=53.9473684210526, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI45643119, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI260275230, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI260274832, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI62530384, Length=177, Percent_Identity=31.0734463276836, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI157694520, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=38.3720930232558, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI221142681, Length=251, Percent_Identity=36.6533864541833, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1788682, Length=185, Percent_Identity=38.3783783783784, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=34.469696969697, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082183, Length=266, Percent_Identity=29.6992481203008, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790281, Length=185, Percent_Identity=34.5945945945946, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=29.6577946768061, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=250, Percent_Identity=45.2, Blast_Score=200, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=43.6507936507937, Blast_Score=190, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17540714, Length=212, Percent_Identity=39.622641509434, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17558304, Length=230, Percent_Identity=34.3478260869565, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=27.6923076923077, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144276, Length=231, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17508951, Length=231, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17508953, Length=231, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=31.2252964426877, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=25.3846153846154, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144160, Length=203, Percent_Identity=32.0197044334975, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144157, Length=203, Percent_Identity=32.0197044334975, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=25.9615384615385, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=212, Percent_Identity=25.4716981132075, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25141363, Length=209, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=198, Percent_Identity=25.2525252525253, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=44.4897959183673, Blast_Score=197, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=44.4897959183673, Blast_Score=197, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24653139, Length=263, Percent_Identity=37.6425855513308, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24583077, Length=186, Percent_Identity=39.7849462365591, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24583079, Length=186, Percent_Identity=39.7849462365591, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19921000, Length=186, Percent_Identity=39.7849462365591, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21357171, Length=219, Percent_Identity=32.4200913242009, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24650670, Length=252, Percent_Identity=30.952380952381, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19920382, Length=241, Percent_Identity=29.045643153527, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=25.8064516129032, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24583165, Length=253, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921018, Length=212, Percent_Identity=31.1320754716981, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571730, Length=140, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571729, Length=140, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654903, Length=188, Percent_Identity=25, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27493; Mature: 27493

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKNLLIETADGVATLTVNRPQALNALNSEVLTELASAFYQLEYDPAVRVVVLTGAGEK
CCHHHHEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCE
AFVAGADIKEMAAMSSFEGHQFALKGQHCMMAMEKMKTPVIAAVNGFALGGGLELALGCD
EEEECCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCEEEEECCEEECCCEEEEEECE
FIYASEKAKLGFPEVTLGIIPGFGGTQNLARLIGKNRANELIFTGRMIAADKAQAWGIVN
EEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECEEEECCCHHHHHHHH
EVFAPEELLVKAKETAAAIAGVGPLGVTYAKNAIANGLNMGKEDGFRYEASLFGVLFGTA
HHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHEEEEEEECCC
DQKEGMGAFVEKRKAVFTGK
CCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFKNLLIETADGVATLTVNRPQALNALNSEVLTELASAFYQLEYDPAVRVVVLTGAGEK
CCHHHHEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCE
AFVAGADIKEMAAMSSFEGHQFALKGQHCMMAMEKMKTPVIAAVNGFALGGGLELALGCD
EEEECCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCEEEEECCEEECCCEEEEEECE
FIYASEKAKLGFPEVTLGIIPGFGGTQNLARLIGKNRANELIFTGRMIAADKAQAWGIVN
EEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECEEEECCCHHHHHHHH
EVFAPEELLVKAKETAAAIAGVGPLGVTYAKNAIANGLNMGKEDGFRYEASLFGVLFGTA
HHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEHHEEEEEEECCC
DQKEGMGAFVEKRKAVFTGK
CCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]