Click here to switch to the map view.

The map label for this gene is fixB [H]

Identifier: 78222921

GI number: 78222921

Start: 1924142

End: 1925056

Strand: Reverse

Name: fixB [H]

Synonym: Gmet_1712

Alternate gene names: 78222921

Gene position: 1925056-1924142 (Counterclockwise)

Preceding gene: 78222922

Following gene: 78222920

Centisome position: 48.16

GC content: 63.93

Gene sequence:

>915_bases
ATGAAAGCACTGCTTGTCTGCGAATATCGCGAAGGAAAACTCCTCGATACAACCTACGAACTCCTCGCCTTTGCCGACCG
CATCGGCGCCGAGAAGGCCATGGTCCTCATCGGGAGCGACAGCGCCCTGCCCGCCTGCAATAGCACAGTTTACCTGGCCG
AGGCGGCGAAATACGGCGAATACAACCCGGACGTGCACAAGAAGATCGTTCTCGATGCGGTCCAGCGGGAAAACGCCGAC
TGCATCGTCTTCGTCCACTCTTCCTACGGCTGGGACCTGGCCCCTCGGGTGGCGGCGGCTCTCAGGGCCGGGCAGGTGTC
GGAGATCGTCGGTGTTGTGGACGGCGGCTACGAGGTGGGGTGCTGCAACGCCAAGATGCGCCGCGCCGTAACCCCCACAA
GCGGCAAGGCGGTCCTCACCGTCCAGGCCGGCGCCTTCAGCTTCACGGGCACTCCCCAGGGGACGCCAAAGGTGGAGCGC
ATCGACATACCCGATGGGGCGACGCCGGTGGAATTTGTCGGCTACGAGCCCGCCGAGAAAAAGGACGTGGACCTGACCCG
GGCCGAGGTGATCGTCAGCGCCGGTCGGGGCGTGGGGAAAAAGGACAATATCCCCGTTATCCAGGCTCTGGCCAAGGCCC
TTGGCGGAGAATTGGGGGCGAGCCGGCCGGTGGTGGATGCCGGCTGGGTGGATCACAGCCACCAGGTGGGGACCACCGGC
CAGAGCGTGAGCCCCAAGCTCTACGTGGCCTGCGGCATTTCGGGAGCGATCCAGCATCTGGCCGGCATGAAGAAATCGGA
CTTCGTTGTCGCCATCAACAAGGACAAGGACGCCCCCATCGGGGAAGTTGCCGATGTCCTCGTGGTGGCCGACGTGATGC
AATTCGTGCCGGCTCTCACGGCCAAACTGCAGTGA

Upstream 100 bases:

>100_bases
GGCGGAATCGTGCTGGAAGGTGATGTGGGGAACCTGGTGGAGCAGCTCTACGGGATCCTGAAAGAAAAAACGACCGTGCT
CCGGTAGGAGGAGAAACCAT

Downstream 100 bases:

>100_bases
ACCGGGCTGACAGAGGAGGAGCCATGAAGCCCCTTAAAGGAATGGTTGTCGTGAACCTGGCCGTGAATCTTCCCGGCCCC
GCCGCCGCCCGGCGCCTCCG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKALLVCEYREGKLLDTTYELLAFADRIGAEKAMVLIGSDSALPACNSTVYLAEAAKYGEYNPDVHKKIVLDAVQRENAD
CIVFVHSSYGWDLAPRVAAALRAGQVSEIVGVVDGGYEVGCCNAKMRRAVTPTSGKAVLTVQAGAFSFTGTPQGTPKVER
IDIPDGATPVEFVGYEPAEKKDVDLTRAEVIVSAGRGVGKKDNIPVIQALAKALGGELGASRPVVDAGWVDHSHQVGTTG
QSVSPKLYVACGISGAIQHLAGMKKSDFVVAINKDKDAPIGEVADVLVVADVMQFVPALTAKLQ

Sequences:

>Translated_304_residues
MKALLVCEYREGKLLDTTYELLAFADRIGAEKAMVLIGSDSALPACNSTVYLAEAAKYGEYNPDVHKKIVLDAVQRENAD
CIVFVHSSYGWDLAPRVAAALRAGQVSEIVGVVDGGYEVGCCNAKMRRAVTPTSGKAVLTVQAGAFSFTGTPQGTPKVER
IDIPDGATPVEFVGYEPAEKKDVDLTRAEVIVSAGRGVGKKDNIPVIQALAKALGGELGASRPVVDAGWVDHSHQVGTTG
QSVSPKLYVACGISGAIQHLAGMKKSDFVVAINKDKDAPIGEVADVLVVADVMQFVPALTAKLQ
>Mature_304_residues
MKALLVCEYREGKLLDTTYELLAFADRIGAEKAMVLIGSDSALPACNSTVYLAEAAKYGEYNPDVHKKIVLDAVQRENAD
CIVFVHSSYGWDLAPRVAAALRAGQVSEIVGVVDGGYEVGCCNAKMRRAVTPTSGKAVLTVQAGAFSFTGTPQGTPKVER
IDIPDGATPVEFVGYEPAEKKDVDLTRAEVIVSAGRGVGKKDNIPVIQALAKALGGELGASRPVVDAGWVDHSHQVGTTG
QSVSPKLYVACGISGAIQHLAGMKKSDFVVAINKDKDAPIGEVADVLVVADVMQFVPALTAKLQ

Specific function: May play a role in a redox process [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=315, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI189181759, Length=262, Percent_Identity=35.8778625954198, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1786226, Length=246, Percent_Identity=34.9593495934959, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787990, Length=122, Percent_Identity=40.1639344262295, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082157, Length=246, Percent_Identity=31.3008130081301, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=318, Percent_Identity=37.4213836477987, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325261, Length=226, Percent_Identity=36.7256637168142, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17136898, Length=310, Percent_Identity=37.741935483871, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24652801, Length=310, Percent_Identity=37.741935483871, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31984; Mature: 31984

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLVCEYREGKLLDTTYELLAFADRIGAEKAMVLIGSDSALPACNSTVYLAEAAKYGE
CCEEEEEECCCCCEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEHHHCCC
YNPDVHKKIVLDAVQRENADCIVFVHSSYGWDLAPRVAAALRAGQVSEIVGVVDGGYEVG
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHEEECCCEEEE
CCNAKMRRAVTPTSGKAVLTVQAGAFSFTGTPQGTPKVERIDIPDGATPVEFVGYEPAEK
ECCHHHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCEEEEECCCCCCCEEEECCCCCCC
KDVDLTRAEVIVSAGRGVGKKDNIPVIQALAKALGGELGASRPVVDAGWVDHSHQVGTTG
CCCCHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC
QSVSPKLYVACGISGAIQHLAGMKKSDFVVAINKDKDAPIGEVADVLVVADVMQFVPALT
CCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AKLQ
HCCC
>Mature Secondary Structure
MKALLVCEYREGKLLDTTYELLAFADRIGAEKAMVLIGSDSALPACNSTVYLAEAAKYGE
CCEEEEEECCCCCEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEHHHCCC
YNPDVHKKIVLDAVQRENADCIVFVHSSYGWDLAPRVAAALRAGQVSEIVGVVDGGYEVG
CCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHEEECCCEEEE
CCNAKMRRAVTPTSGKAVLTVQAGAFSFTGTPQGTPKVERIDIPDGATPVEFVGYEPAEK
ECCHHHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCEEEEECCCCCCCEEEECCCCCCC
KDVDLTRAEVIVSAGRGVGKKDNIPVIQALAKALGGELGASRPVVDAGWVDHSHQVGTTG
CCCCHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC
QSVSPKLYVACGISGAIQHLAGMKKSDFVVAINKDKDAPIGEVADVLVVADVMQFVPALT
CCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
AKLQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7875566 [H]