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The map label for this gene is pbpG [H]

Identifier: 78222880

GI number: 78222880

Start: 1878288

End: 1880369

Strand: Direct

Name: pbpG [H]

Synonym: Gmet_1671

Alternate gene names: 78222880

Gene position: 1878288-1880369 (Clockwise)

Preceding gene: 78222872

Following gene: 78222885

Centisome position: 46.99

GC content: 58.6

Gene sequence:

>2082_bases
TTGCCTCTTCTGTCGCCATCGACGAATCTCCCGTTAATAGACAGAACTACGGCAACGCCCAGTCTCTTTACGGAGCGAAC
TGTCATCGTGGTTTCCTGTTTGATCGTTACCTTCAAGCGTACGGTTCTTTTGACTTCATTCGGCCTGTTCACGGCTCTCC
TTCTGGTCTCATCGGCTCTAGCCCAGGGGAATATCGCCAAGTATCCCTATCTGCCGTCAGGCTATTCGTCGGTCAAGGTT
TTTGACCGCAGCGGACGGTTTGTGGGCCGTATCCTCCCCGAGAAACGCTACTGGGTCTCCATAGATCACATCCCCGCTTT
CCTGCAAAAGGCGGTGGTGGCTGTGGAAGATGCACGGTTTTTTGAGCATGGAGGCATTGATATTCGCGGGATCGCCCGGG
CGCTCGTGAAGGATGTGGTCAAGGGCAAGCTGGTGGAAGGGGGATCAACCATAACCCAGCAACTGATCAAGAACCGATAT
CTCTCCGGGGAGAAAACCATCGAGCGGAAGCTTGAGGAAGCCCGGATGGCCATGGAGTATGAGAAGATCTATACCAAGAA
GCAGATTCTTGAGATGTATTTCAACGAGATTTACTACGGCAATGGGGCGTGGGGCATTGCCCAGGCGGCCCGGGTCTATT
TTGACAAGACCCCCGATCAGTTGACCGATGCCGAATGCGCCCTGCTGGCTGGAGTGCCCAAGAACCCGGGCCGGTACAAC
CCCCTCGGGAAAGCGGTCGATGTCAGCAGACGAAGGGACGTGGTTCTTGCTCGCATGCTGGACCTCAAGATGATTTCGGC
GCGGCAGAAGCAGAAGTTGAGAACCCGCCCCATTACAACGGTGCAGCGCAGTCAGGCGCCCTACTATCTGGCCCATATCC
GGAACGAGCTTGTGGAGCGCTTCGGCCCTCAGATCATCGAACGGGGGGGACTGGAAGTTACTGCCGCCATGGACTTGAAC
CTGCAGAAACTGGCCGAAAAGACCTTGAAGGAAGGGGTGAAAAGGATTTCCCCCGAGCTTCAGGGGGCATTGGTTTCTCT
GGATCCTGCAACGGGTGATGTGCTGGCAGCCGTCGGTGGGGTAGACTTCACGAAGAGCCCCTATGATCGCGCCTTCCTTG
CCAGGCGTCAACCCGGCTCAGCCATCAAGCCGCTGATCTATGCCGCAGCCTTGGAAATGGGGATTACCGCCGGCAGCGTC
TGGGATGATACGCCGGTTGCCTACGATCGCGGATACAATCAGACCTGGAAGCCCCTGAACTACGGGAAGGAGCGGTATGG
CCAACTGTCGCTCCGGCGAGCCCTGGCGTACTCGAACAACATCATAGCGGTCAAGTTGCTGGACACGATCGGAGTCCCGT
ACTTTGTCGATTTTGCCCACAAGGCAGGGCTTCCCCTGCGTCCCAACAACGATCTTTCCCTGGCCCTCGGAACGGAAGAC
GTTACCTTGCGCGACCTGGTAAGAGCATACACCCCCTTGGCCAACGGAGGGCTCAGGTCCGAACCGAGAACAATCGTGCG
TATCTATGACAGGAATCGCCGCGCCTGGACGGAAAACGCTCCGTCAGTTGCGCCGGCCCTCTCGCCGGCGGCCGCCTTTG
TCACCACCCGGATGCTCAGGGACGTCATGGTGTACGGCACCGCAAAATCCCTCAAATCCTTCAGCCAGAAGCGACCGTCC
GCCGGGAAGACCGGTACCACCGACGATTACCGCGATGCCTGGTTCATCGGCTACACTCCCCAGGTGCTGACCGGCATCTG
GGTGGGATACGACAAGCCGCGGCCGGGGGGGAGAGGGTTTACCGGCGGGGCAGTGGCGGCGCCAATCTGGCAACGGTTCA
TGGGGCCGGCTCTGGCATCAAAGCCGGTTGCGGATTTTCCGAAACCCGATACGGTTGTCTCCGTTTCCATCGACCCGGCG
ACCGGTTACCTGGCAACGCCGGACTGCCCGGAAAAGCGCGACGAATTCTATGTCGAGGGGACCCAACCCACCGAATACTG
TCCCAAACATGGCGGAGATCGCCTTAATCAGGTACCGCCCGTCCTGTCCCTGCCCAAGGAGGAGGCTCCGCAATCCGAGT
GA

Upstream 100 bases:

>100_bases
ATGGTCCGACAAGTTCCCGTTGCGACAAACCAGTGAGCCTGTCTCCGCCACCCTTGACACATCTTCTGGAAGAATGTAGC
GTCGTACGGAGTTTCCATCG

Downstream 100 bases:

>100_bases
ATTCTCTCTCCTCCTTTCCCTTCATCACACCTGTTGGCACTATTGCTCGCACTGCCAGTCATCCTGCCGTTTTGAACATG
ATGACCTCGGCCTCGGCCAT

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MPLLSPSTNLPLIDRTTATPSLFTERTVIVVSCLIVTFKRTVLLTSFGLFTALLLVSSALAQGNIAKYPYLPSGYSSVKV
FDRSGRFVGRILPEKRYWVSIDHIPAFLQKAVVAVEDARFFEHGGIDIRGIARALVKDVVKGKLVEGGSTITQQLIKNRY
LSGEKTIERKLEEARMAMEYEKIYTKKQILEMYFNEIYYGNGAWGIAQAARVYFDKTPDQLTDAECALLAGVPKNPGRYN
PLGKAVDVSRRRDVVLARMLDLKMISARQKQKLRTRPITTVQRSQAPYYLAHIRNELVERFGPQIIERGGLEVTAAMDLN
LQKLAEKTLKEGVKRISPELQGALVSLDPATGDVLAAVGGVDFTKSPYDRAFLARRQPGSAIKPLIYAAALEMGITAGSV
WDDTPVAYDRGYNQTWKPLNYGKERYGQLSLRRALAYSNNIIAVKLLDTIGVPYFVDFAHKAGLPLRPNNDLSLALGTED
VTLRDLVRAYTPLANGGLRSEPRTIVRIYDRNRRAWTENAPSVAPALSPAAAFVTTRMLRDVMVYGTAKSLKSFSQKRPS
AGKTGTTDDYRDAWFIGYTPQVLTGIWVGYDKPRPGGRGFTGGAVAAPIWQRFMGPALASKPVADFPKPDTVVSVSIDPA
TGYLATPDCPEKRDEFYVEGTQPTEYCPKHGGDRLNQVPPVLSLPKEEAPQSE

Sequences:

>Translated_693_residues
MPLLSPSTNLPLIDRTTATPSLFTERTVIVVSCLIVTFKRTVLLTSFGLFTALLLVSSALAQGNIAKYPYLPSGYSSVKV
FDRSGRFVGRILPEKRYWVSIDHIPAFLQKAVVAVEDARFFEHGGIDIRGIARALVKDVVKGKLVEGGSTITQQLIKNRY
LSGEKTIERKLEEARMAMEYEKIYTKKQILEMYFNEIYYGNGAWGIAQAARVYFDKTPDQLTDAECALLAGVPKNPGRYN
PLGKAVDVSRRRDVVLARMLDLKMISARQKQKLRTRPITTVQRSQAPYYLAHIRNELVERFGPQIIERGGLEVTAAMDLN
LQKLAEKTLKEGVKRISPELQGALVSLDPATGDVLAAVGGVDFTKSPYDRAFLARRQPGSAIKPLIYAAALEMGITAGSV
WDDTPVAYDRGYNQTWKPLNYGKERYGQLSLRRALAYSNNIIAVKLLDTIGVPYFVDFAHKAGLPLRPNNDLSLALGTED
VTLRDLVRAYTPLANGGLRSEPRTIVRIYDRNRRAWTENAPSVAPALSPAAAFVTTRMLRDVMVYGTAKSLKSFSQKRPS
AGKTGTTDDYRDAWFIGYTPQVLTGIWVGYDKPRPGGRGFTGGAVAAPIWQRFMGPALASKPVADFPKPDTVVSVSIDPA
TGYLATPDCPEKRDEFYVEGTQPTEYCPKHGGDRLNQVPPVLSLPKEEAPQSE
>Mature_692_residues
PLLSPSTNLPLIDRTTATPSLFTERTVIVVSCLIVTFKRTVLLTSFGLFTALLLVSSALAQGNIAKYPYLPSGYSSVKVF
DRSGRFVGRILPEKRYWVSIDHIPAFLQKAVVAVEDARFFEHGGIDIRGIARALVKDVVKGKLVEGGSTITQQLIKNRYL
SGEKTIERKLEEARMAMEYEKIYTKKQILEMYFNEIYYGNGAWGIAQAARVYFDKTPDQLTDAECALLAGVPKNPGRYNP
LGKAVDVSRRRDVVLARMLDLKMISARQKQKLRTRPITTVQRSQAPYYLAHIRNELVERFGPQIIERGGLEVTAAMDLNL
QKLAEKTLKEGVKRISPELQGALVSLDPATGDVLAAVGGVDFTKSPYDRAFLARRQPGSAIKPLIYAAALEMGITAGSVW
DDTPVAYDRGYNQTWKPLNYGKERYGQLSLRRALAYSNNIIAVKLLDTIGVPYFVDFAHKAGLPLRPNNDLSLALGTEDV
TLRDLVRAYTPLANGGLRSEPRTIVRIYDRNRRAWTENAPSVAPALSPAAAFVTTRMLRDVMVYGTAKSLKSFSQKRPSA
GKTGTTDDYRDAWFIGYTPQVLTGIWVGYDKPRPGGRGFTGGAVAAPIWQRFMGPALASKPVADFPKPDTVVSVSIDPAT
GYLATPDCPEKRDEFYVEGTQPTEYCPKHGGDRLNQVPPVLSLPKEEAPQSE

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=564, Percent_Identity=30.8510638297872, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1788867, Length=601, Percent_Identity=29.6173044925125, Blast_Score=183, Evalue=4e-47,
Organism=Escherichia coli, GI87082258, Length=261, Percent_Identity=37.9310344827586, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI1789601, Length=233, Percent_Identity=33.0472103004292, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 76606; Mature: 76475

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLSPSTNLPLIDRTTATPSLFTERTVIVVSCLIVTFKRTVLLTSFGLFTALLLVSSAL
CCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGNIAKYPYLPSGYSSVKVFDRSGRFVGRILPEKRYWVSIDHIPAFLQKAVVAVEDARF
HCCCCCCCCCCCCCCCCEEEEECCCCEEEHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
FEHGGIDIRGIARALVKDVVKGKLVEGGSTITQQLIKNRYLSGEKTIERKLEEARMAMEY
HHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EKIYTKKQILEMYFNEIYYGNGAWGIAQAARVYFDKTPDQLTDAECALLAGVPKNPGRYN
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCCCCCC
PLGKAVDVSRRRDVVLARMLDLKMISARQKQKLRTRPITTVQRSQAPYYLAHIRNELVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHH
FGPQIIERGGLEVTAAMDLNLQKLAEKTLKEGVKRISPELQGALVSLDPATGDVLAAVGG
HCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCHHHCCEEEEECCCCCHHHHHHCC
VDFTKSPYDRAFLARRQPGSAIKPLIYAAALEMGITAGSVWDDTPVAYDRGYNQTWKPLN
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCC
YGKERYGQLSLRRALAYSNNIIAVKLLDTIGVPYFVDFAHKAGLPLRPNNDLSLALGTED
CCHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCEEHHHHHCCCCCCCCCCCEEEECCCC
VTLRDLVRAYTPLANGGLRSEPRTIVRIYDRNRRAWTENAPSVAPALSPAAAFVTTRMLR
CHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DVMVYGTAKSLKSFSQKRPSAGKTGTTDDYRDAWFIGYTPQVLTGIWVGYDKPRPGGRGF
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCC
TGGAVAAPIWQRFMGPALASKPVADFPKPDTVVSVSIDPATGYLATPDCPEKRDEFYVEG
CCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEC
TQPTEYCPKHGGDRLNQVPPVLSLPKEEAPQSE
CCCHHHCCCCCCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLSPSTNLPLIDRTTATPSLFTERTVIVVSCLIVTFKRTVLLTSFGLFTALLLVSSAL
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGNIAKYPYLPSGYSSVKVFDRSGRFVGRILPEKRYWVSIDHIPAFLQKAVVAVEDARF
HCCCCCCCCCCCCCCCCEEEEECCCCEEEHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
FEHGGIDIRGIARALVKDVVKGKLVEGGSTITQQLIKNRYLSGEKTIERKLEEARMAMEY
HHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EKIYTKKQILEMYFNEIYYGNGAWGIAQAARVYFDKTPDQLTDAECALLAGVPKNPGRYN
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCHHCCCCCCEEECCCCCCCCCC
PLGKAVDVSRRRDVVLARMLDLKMISARQKQKLRTRPITTVQRSQAPYYLAHIRNELVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHH
FGPQIIERGGLEVTAAMDLNLQKLAEKTLKEGVKRISPELQGALVSLDPATGDVLAAVGG
HCHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCHHHCCEEEEECCCCCHHHHHHCC
VDFTKSPYDRAFLARRQPGSAIKPLIYAAALEMGITAGSVWDDTPVAYDRGYNQTWKPLN
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCC
YGKERYGQLSLRRALAYSNNIIAVKLLDTIGVPYFVDFAHKAGLPLRPNNDLSLALGTED
CCHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCEEHHHHHCCCCCCCCCCCEEEECCCC
VTLRDLVRAYTPLANGGLRSEPRTIVRIYDRNRRAWTENAPSVAPALSPAAAFVTTRMLR
CHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DVMVYGTAKSLKSFSQKRPSAGKTGTTDDYRDAWFIGYTPQVLTGIWVGYDKPRPGGRGF
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCC
TGGAVAAPIWQRFMGPALASKPVADFPKPDTVVSVSIDPATGYLATPDCPEKRDEFYVEG
CCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEC
TQPTEYCPKHGGDRLNQVPPVLSLPKEEAPQSE
CCCHHHCCCCCCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]