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The map label for this gene is mdtA [H]

Identifier: 78222860

GI number: 78222860

Start: 1854460

End: 1855683

Strand: Direct

Name: mdtA [H]

Synonym: Gmet_1651

Alternate gene names: 78222860

Gene position: 1854460-1855683 (Clockwise)

Preceding gene: 78222859

Following gene: 78222861

Centisome position: 46.39

GC content: 63.4

Gene sequence:

>1224_bases
ATGAATCTATCTCTCTCGCCCCGCGACCCGTCGAGAAGCGGCATCCTGTCCCGTCGCGTTCGCCGACTGGTCGTGCAGGG
GGCAGCTTATTCTCTCATTGTCACACTTGCCGCCTGCGCCAAGAAAGAGCAGAAACCTGCTGCCAAGCCGCCGGTCCCGG
TAGCGATCGCCACGGTCGAGCGAAAGACCGTCCCGGTCCAGATCAAGGCCATCGGCAACGTGGAGCCCTACGCTACCGTG
GCCGTCAAGGCTCAGGTGAACGGCGAGGTGCTGAAGGTCCATTTCACCGAGGGACAGGACGTGAAACGGGGTGACCTCCT
TTTCGCCATTGACCCGCGCACCTATCAGGCAGCAGTGAAGAAAGCCGAAGCCAATCTTTCCCGTAACCTCGTCCAGGCAC
GGAACGCCCGGCAGGACGCGGAGCGCTACGCCCAACTGGTGAAGGAGGGCATCGTGACTTCGGAGCAGTACGAGCAGTAC
CGGACCAGGGCCGAGGCCTTTGCCGCCGATGTGTCCGCCGACCGGGCCGCCGTCGAGAACGCGAAGGTGGAGCTTTCCTA
CTGCTTCATCCGCTCCCCCTTGACCGGCCGCACCGGGAATCTGGCGGTCCATGCGGGGAACATCGTAAAGGCCAATGAGA
ACCCCCCCCTGGTCACCATCAACCAGATTACGCCGGTCTACGTGGCGTTTTCCATCCCCGAAAAGGACCTCGCCGAGGTC
AAGCGCCGCATGGCTGCAGGAAAGCTGGCGGTGGAGGCGACCATTCCCAACGATGCCGGTCCCGCTGAGCAGGGGATGAT
CTCCTTCCTCGACAACACGGTTGACGTGGCCACCGGCACCATCAAACTCAAGGGGACCTTCGAGAACAGGGCACGTCGCC
TCTGGCCCGGGCAGTTCGCCAACGTGGTTGTGACCCTCGCGGCCAGGCCCAATGCGATTGTGGTCCCGGCCCAGGCGATT
CAGACCGGCCAGAGCGGTCCCTATGTCTTTGTGGTAAAGGCTGACTCTTCGGTAGAAATCCGGCCGGTGACGCCGGGCAT
TGCCTACGAAGGGGTCACCATTATCGAGCAGGGGCTCGCGCCCGGTGAAAGGGTTGTGACCGACGGCCAGATGAGGCTCA
CGCCCAAGGCCAGGGTGACGGAAAAACCGGGACCGGGGACCAGGGACCAAGGGCCGGCAAACCCCCGGCAAGCTTCTGGC
CAGCCCAAGGGCCAGCAACCATGA

Upstream 100 bases:

>100_bases
GGGGTTCAGTTGTCGGACACGGAGGGTGATTCCCTCTACGAGCGGCACGTCCACAACTGAAACCATCCTCTCATCGCTCC
AAACCCACCGGAGATACACC

Downstream 100 bases:

>100_bases
GCATCGCCGAGGTTTTCATCCGGCGGCCGGTCATGACGAGCCTCGTCATGCTGGCTGTCATGCTCTTCGGTCTCCTCGCC
TACAGCAAGCTGCCGGTCAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNLSLSPRDPSRSGILSRRVRRLVVQGAAYSLIVTLAACAKKEQKPAAKPPVPVAIATVERKTVPVQIKAIGNVEPYATV
AVKAQVNGEVLKVHFTEGQDVKRGDLLFAIDPRTYQAAVKKAEANLSRNLVQARNARQDAERYAQLVKEGIVTSEQYEQY
RTRAEAFAADVSADRAAVENAKVELSYCFIRSPLTGRTGNLAVHAGNIVKANENPPLVTINQITPVYVAFSIPEKDLAEV
KRRMAAGKLAVEATIPNDAGPAEQGMISFLDNTVDVATGTIKLKGTFENRARRLWPGQFANVVVTLAARPNAIVVPAQAI
QTGQSGPYVFVVKADSSVEIRPVTPGIAYEGVTIIEQGLAPGERVVTDGQMRLTPKARVTEKPGPGTRDQGPANPRQASG
QPKGQQP

Sequences:

>Translated_407_residues
MNLSLSPRDPSRSGILSRRVRRLVVQGAAYSLIVTLAACAKKEQKPAAKPPVPVAIATVERKTVPVQIKAIGNVEPYATV
AVKAQVNGEVLKVHFTEGQDVKRGDLLFAIDPRTYQAAVKKAEANLSRNLVQARNARQDAERYAQLVKEGIVTSEQYEQY
RTRAEAFAADVSADRAAVENAKVELSYCFIRSPLTGRTGNLAVHAGNIVKANENPPLVTINQITPVYVAFSIPEKDLAEV
KRRMAAGKLAVEATIPNDAGPAEQGMISFLDNTVDVATGTIKLKGTFENRARRLWPGQFANVVVTLAARPNAIVVPAQAI
QTGQSGPYVFVVKADSSVEIRPVTPGIAYEGVTIIEQGLAPGERVVTDGQMRLTPKARVTEKPGPGTRDQGPANPRQASG
QPKGQQP
>Mature_407_residues
MNLSLSPRDPSRSGILSRRVRRLVVQGAAYSLIVTLAACAKKEQKPAAKPPVPVAIATVERKTVPVQIKAIGNVEPYATV
AVKAQVNGEVLKVHFTEGQDVKRGDLLFAIDPRTYQAAVKKAEANLSRNLVQARNARQDAERYAQLVKEGIVTSEQYEQY
RTRAEAFAADVSADRAAVENAKVELSYCFIRSPLTGRTGNLAVHAGNIVKANENPPLVTINQITPVYVAFSIPEKDLAEV
KRRMAAGKLAVEATIPNDAGPAEQGMISFLDNTVDVATGTIKLKGTFENRARRLWPGQFANVVVTLAARPNAIVVPAQAI
QTGQSGPYVFVVKADSSVEIRPVTPGIAYEGVTIIEQGLAPGERVVTDGQMRLTPKARVTEKPGPGTRDQGPANPRQASG
QPKGQQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=350, Percent_Identity=35.1428571428571, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1789929, Length=353, Percent_Identity=31.1614730878187, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786668, Length=356, Percent_Identity=33.1460674157303, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789665, Length=356, Percent_Identity=32.0224719101124, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790519, Length=215, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081951, Length=162, Percent_Identity=26.5432098765432, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43720; Mature: 43720

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLSPRDPSRSGILSRRVRRLVVQGAAYSLIVTLAACAKKEQKPAAKPPVPVAIATVE
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
RKTVPVQIKAIGNVEPYATVAVKAQVNGEVLKVHFTEGQDVKRGDLLFAIDPRTYQAAVK
CCEEEEEEEEECCCCCEEEEEEEEEECCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHH
KAEANLSRNLVQARNARQDAERYAQLVKEGIVTSEQYEQYRTRAEAFAADVSADRAAVEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCC
AKVELSYCFIRSPLTGRTGNLAVHAGNIVKANENPPLVTINQITPVYVAFSIPEKDLAEV
CEEEEEEEEEECCCCCCCCCEEEEECCEEEECCCCCEEEECCCCEEEEEEECCHHHHHHH
KRRMAAGKLAVEATIPNDAGPAEQGMISFLDNTVDVATGTIKLKGTFENRARRLWPGQFA
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECHHHHHHHCCCCCCC
NVVVTLAARPNAIVVPAQAIQTGQSGPYVFVVKADSSVEIRPVTPGIAYEGVTIIEQGLA
EEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHCCC
PGERVVTDGQMRLTPKARVTEKPGPGTRDQGPANPRQASGQPKGQQP
CCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLSLSPRDPSRSGILSRRVRRLVVQGAAYSLIVTLAACAKKEQKPAAKPPVPVAIATVE
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
RKTVPVQIKAIGNVEPYATVAVKAQVNGEVLKVHFTEGQDVKRGDLLFAIDPRTYQAAVK
CCEEEEEEEEECCCCCEEEEEEEEEECCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHH
KAEANLSRNLVQARNARQDAERYAQLVKEGIVTSEQYEQYRTRAEAFAADVSADRAAVEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCC
AKVELSYCFIRSPLTGRTGNLAVHAGNIVKANENPPLVTINQITPVYVAFSIPEKDLAEV
CEEEEEEEEEECCCCCCCCCEEEEECCEEEECCCCCEEEECCCCEEEEEEECCHHHHHHH
KRRMAAGKLAVEATIPNDAGPAEQGMISFLDNTVDVATGTIKLKGTFENRARRLWPGQFA
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEEEECHHHHHHHCCCCCCC
NVVVTLAARPNAIVVPAQAIQTGQSGPYVFVVKADSSVEIRPVTPGIAYEGVTIIEQGLA
EEEEEEECCCCEEEEEHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHCCC
PGERVVTDGQMRLTPKARVTEKPGPGTRDQGPANPRQASGQPKGQQP
CCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA