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The map label for this gene is fabD [H]

Identifier: 78222810

GI number: 78222810

Start: 1801106

End: 1802032

Strand: Direct

Name: fabD [H]

Synonym: Gmet_1600

Alternate gene names: 78222810

Gene position: 1801106-1802032 (Clockwise)

Preceding gene: 78222809

Following gene: 78222811

Centisome position: 45.06

GC content: 57.28

Gene sequence:

>927_bases
ATGAGTAGACGAGCATTCATATTCCCCGGCCAGGGTTCGCAATATCCCGGCATGGGAAAGGATCTTGCGGATAACTTCGC
ACTAGCCCGGAAGACATTCGAGGAGGCTGATGACGCCCTTGGGGACAACTTGTCTCGCCTCTGTTTCGATGGTCCCGAAG
ACCAATTGAAGCTCACCGCCAACACGCAGCCCTCTATCCTCACCGTTAGTGTGGCTGCCCTGCGGGTCCTTCAAGAGGAG
ACCGGCTTGAGTGCACAGTATTTTGCCGGTCACTCTCTTGGAGAGTATTCCGCATTGGTGGCTGCCGGCGTCATTCAGTT
CGCAGACGCGGTTAGAACGGTTCGTGCTCGCGGGACCTTTATGCAGGAGGCTGTGCCTGTCGGCGTTGGAGCCATGGCAG
CCATGTTGAGTATCGAGCCCGACGTCCTTGCCGCTATCTGCGCTGAGGCTGCCCAAGGCGAAGAGGTCTCCCCTGCCAAC
TTCAATTCGCCTGGACAGATTGTCATTGCAGGCCACACGGGGGCCGTCAATCGGGCCATAGAGATTGCCAAAGCCAAGGG
GTTCCGCAAAGCGATGCTCCTTCCTGTAAGTGCCCCCTTCCATTCGAGCCTCATGGTGCCTGCCGGTGAAAGGCTTGCCG
GCGTCCTTGCCCCAATTACTGTTGGTGCATTCAGTGCGCCCGTGGTGACGAACGTGGAGGCTAAACCCAATGACGACAAA
GCACGGGTGAAAGAGCTTCTTGTTCGTCAGGTGAGTGCTCCGGTTCTCTGGGATGCATCGGTACGCGAAATGGTGGCTCT
TGGTGTTACGGAGTTCGTGGAGGTTGGCCCGGGCAAGGTTCTGTCGGGTCTGGTCAAGAGGATTGACAAAGGAGTGTCCA
CGAAGAATGTTGAAGACGCGGCAGGAATTAAGGCCATCGGGGAGTAG

Upstream 100 bases:

>100_bases
TAAACGAGGGGGATATTGTCCTCTTTGATGCCTTCGGCGGTGGCCTCACGTGGGCCTCTGTTCTGCTGCGCTGGTAATCT
CTCTCCCAAAAGGAACTGCT

Downstream 100 bases:

>100_bases
GGAAACCATGAGTCTTGAAGGTAAGGTTGCAATCGTAACGGGAGCCTCAAGGGGAATCGGCAGGGCCATCGCCCTAAAAC
TCGCCAGGGAGGGGGCCAGT

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSRRAFIFPGQGSQYPGMGKDLADNFALARKTFEEADDALGDNLSRLCFDGPEDQLKLTANTQPSILTVSVAALRVLQEE
TGLSAQYFAGHSLGEYSALVAAGVIQFADAVRTVRARGTFMQEAVPVGVGAMAAMLSIEPDVLAAICAEAAQGEEVSPAN
FNSPGQIVIAGHTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAGVLAPITVGAFSAPVVTNVEAKPNDDK
ARVKELLVRQVSAPVLWDASVREMVALGVTEFVEVGPGKVLSGLVKRIDKGVSTKNVEDAAGIKAIGE

Sequences:

>Translated_308_residues
MSRRAFIFPGQGSQYPGMGKDLADNFALARKTFEEADDALGDNLSRLCFDGPEDQLKLTANTQPSILTVSVAALRVLQEE
TGLSAQYFAGHSLGEYSALVAAGVIQFADAVRTVRARGTFMQEAVPVGVGAMAAMLSIEPDVLAAICAEAAQGEEVSPAN
FNSPGQIVIAGHTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAGVLAPITVGAFSAPVVTNVEAKPNDDK
ARVKELLVRQVSAPVLWDASVREMVALGVTEFVEVGPGKVLSGLVKRIDKGVSTKNVEDAAGIKAIGE
>Mature_307_residues
SRRAFIFPGQGSQYPGMGKDLADNFALARKTFEEADDALGDNLSRLCFDGPEDQLKLTANTQPSILTVSVAALRVLQEET
GLSAQYFAGHSLGEYSALVAAGVIQFADAVRTVRARGTFMQEAVPVGVGAMAAMLSIEPDVLAAICAEAAQGEEVSPANF
NSPGQIVIAGHTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAGVLAPITVGAFSAPVVTNVEAKPNDDKA
RVKELLVRQVSAPVLWDASVREMVALGVTEFVEVGPGKVLSGLVKRIDKGVSTKNVEDAAGIKAIGE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=31.9078947368421, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=40.1869158878505, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=53.8194444444444, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.3754266211604, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=30.1694915254237, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.5481727574751, Blast_Score=144, Evalue=9e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32185; Mature: 32054

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRAFIFPGQGSQYPGMGKDLADNFALARKTFEEADDALGDNLSRLCFDGPEDQLKLTA
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEE
NTQPSILTVSVAALRVLQEETGLSAQYFAGHSLGEYSALVAAGVIQFADAVRTVRARGTF
CCCCCEEEHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPVGVGAMAAMLSIEPDVLAAICAEAAQGEEVSPANFNSPGQIVIAGHTGAVNRAI
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHH
EIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAGVLAPITVGAFSAPVVTNVEAKPNDDK
HHHHHCCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHH
ARVKELLVRQVSAPVLWDASVREMVALGVTEFVEVGPGKVLSGLVKRIDKGVSTKNVEDA
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHH
AGIKAIGE
HCCCCCCC
>Mature Secondary Structure 
SRRAFIFPGQGSQYPGMGKDLADNFALARKTFEEADDALGDNLSRLCFDGPEDQLKLTA
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEE
NTQPSILTVSVAALRVLQEETGLSAQYFAGHSLGEYSALVAAGVIQFADAVRTVRARGTF
CCCCCEEEHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPVGVGAMAAMLSIEPDVLAAICAEAAQGEEVSPANFNSPGQIVIAGHTGAVNRAI
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHH
EIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAGVLAPITVGAFSAPVVTNVEAKPNDDK
HHHHHCCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHH
ARVKELLVRQVSAPVLWDASVREMVALGVTEFVEVGPGKVLSGLVKRIDKGVSTKNVEDA
HHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHH
AGIKAIGE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]