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The map label for this gene is fabH [H]

Identifier: 78222809

GI number: 78222809

Start: 1800102

End: 1801082

Strand: Direct

Name: fabH [H]

Synonym: Gmet_1599

Alternate gene names: 78222809

Gene position: 1800102-1801082 (Clockwise)

Preceding gene: 78222808

Following gene: 78222810

Centisome position: 45.03

GC content: 53.52

Gene sequence:

>981_bases
ATGGCCAGAGCGAGAATTATCGGCACAGGTTCGGCCGTGCCTGAGATGATACGGACTAATTTCGACCTGGAAAAGATGGT
CGACACCACCGACGACTGGATTACCACCAGGACTGGCATCAGGGAGCGGCGCATCGCTGCTGAAGGCGAATATACTTCAA
CTTTCGCAACCCGTGCGGCTGAGCGGGCTCTCGAGATGGCTGGTGTTACTGCTGAAGAAATTGATCTCCTCATTGTTGCG
ACCGTCACCCCAGATTTTCCCTTTCCATCTACCGCATGCATAGTTCAGAGCAATATCGGAGCGAAAAGGGCCGCTGCGTT
TGATGTCTCCGCTGCCTGTTCGGGGTTTCTCTATGGACTCTCGTTGGCGGACAATGCCATTCGGTCTGGGGGGGCAAGTA
AAGCTCTCATCATCGGCGCCGAGGTTCTGAGCCGAGTTATTGACTGGACCGACAGAAATACCTGCCTTCTTTTCGGTGAC
GGTTCCGGGGCCGTAGTGGTTGAAGCATGCGAAAGTGAACAGGGAGTTCTTTCAACGCACCTGCATAGCGACGGTTCCTA
TTGGGAACTCCTTTATCAGCCCGGTTGCGGCAATCGAAACCCCGCCGTTCAGAAGACCCTGGATGAGAGGAAGAACTTTC
TCCGAATGCAGGGGAATGAGGTGTTCAAGCTTGCCGTGCGGGCTATGGAAGACGCTGCCCTTCAAGCACTGGAAAAGAAT
GGCCTCACTCCCTCGGATATCAGTATTTTTATACCCCACCAGGCTAATCGTAGAATCATCGATGCCATCGGCAAGCGTCT
TGGTTTAAGCGATGACAAAGTCTACGTTAATCTTGATCGATATGGAAACACCTCTTCTGCTTCAATCCCGCTTGCGCTTG
ATGAAGCCAACCGTGGTGGGCGGATAAACGAGGGGGATATTGTCCTCTTTGATGCCTTCGGCGGTGGCCTCACGTGGGCC
TCTGTTCTGCTGCGCTGGTAA

Upstream 100 bases:

>100_bases
AGTGAATCAGCGGCTCGCAGAGAAGTTGGAGACTGAGTTCACCATGTATATGCAGCAGGGCAACGTCCGGGAGTCGGTTG
CCGGCTGAGGGGGCATGGTA

Downstream 100 bases:

>100_bases
TCTCTCTCCCAAAAGGAACTGCTATGAGTAGACGAGCATTCATATTCCCCGGCCAGGGTTCGCAATATCCCGGCATGGGA
AAGGATCTTGCGGATAACTT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MARARIIGTGSAVPEMIRTNFDLEKMVDTTDDWITTRTGIRERRIAAEGEYTSTFATRAAERALEMAGVTAEEIDLLIVA
TVTPDFPFPSTACIVQSNIGAKRAAAFDVSAACSGFLYGLSLADNAIRSGGASKALIIGAEVLSRVIDWTDRNTCLLFGD
GSGAVVVEACESEQGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDERKNFLRMQGNEVFKLAVRAMEDAALQALEKN
GLTPSDISIFIPHQANRRIIDAIGKRLGLSDDKVYVNLDRYGNTSSASIPLALDEANRGGRINEGDIVLFDAFGGGLTWA
SVLLRW

Sequences:

>Translated_326_residues
MARARIIGTGSAVPEMIRTNFDLEKMVDTTDDWITTRTGIRERRIAAEGEYTSTFATRAAERALEMAGVTAEEIDLLIVA
TVTPDFPFPSTACIVQSNIGAKRAAAFDVSAACSGFLYGLSLADNAIRSGGASKALIIGAEVLSRVIDWTDRNTCLLFGD
GSGAVVVEACESEQGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDERKNFLRMQGNEVFKLAVRAMEDAALQALEKN
GLTPSDISIFIPHQANRRIIDAIGKRLGLSDDKVYVNLDRYGNTSSASIPLALDEANRGGRINEGDIVLFDAFGGGLTWA
SVLLRW
>Mature_325_residues
ARARIIGTGSAVPEMIRTNFDLEKMVDTTDDWITTRTGIRERRIAAEGEYTSTFATRAAERALEMAGVTAEEIDLLIVAT
VTPDFPFPSTACIVQSNIGAKRAAAFDVSAACSGFLYGLSLADNAIRSGGASKALIIGAEVLSRVIDWTDRNTCLLFGDG
SGAVVVEACESEQGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDERKNFLRMQGNEVFKLAVRAMEDAALQALEKNG
LTPSDISIFIPHQANRRIIDAIGKRLGLSDDKVYVNLDRYGNTSSASIPLALDEANRGGRINEGDIVLFDAFGGGLTWAS
VLLRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=54.0372670807453, Blast_Score=343, Evalue=6e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35239; Mature: 35108

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARIIGTGSAVPEMIRTNFDLEKMVDTTDDWITTRTGIRERRIAAEGEYTSTFATRAA
CCCEEEEECCCHHHHHHHCCCCHHHHHCCCCCCEEHHCCCHHHHHCCCCCCHHHHHHHHH
ERALEMAGVTAEEIDLLIVATVTPDFPFPSTACIVQSNIGAKRAAAFDVSAACSGFLYGL
HHHHHHHCCCHHHEEEEEEEEECCCCCCCCCEEEEECCCCCCHHHHEEHHHHHHHHHHHH
SLADNAIRSGGASKALIIGAEVLSRVIDWTDRNTCLLFGDGSGAVVVEACESEQGVLSTH
HHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEEE
LHSDGSYWELLYQPGCGNRNPAVQKTLDERKNFLRMQGNEVFKLAVRAMEDAALQALEKN
ECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GLTPSDISIFIPHQANRRIIDAIGKRLGLSDDKVYVNLDRYGNTSSASIPLALDEANRGG
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCC
RINEGDIVLFDAFGGGLTWASVLLRW
CCCCCCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
ARARIIGTGSAVPEMIRTNFDLEKMVDTTDDWITTRTGIRERRIAAEGEYTSTFATRAA
CCEEEEECCCHHHHHHHCCCCHHHHHCCCCCCEEHHCCCHHHHHCCCCCCHHHHHHHHH
ERALEMAGVTAEEIDLLIVATVTPDFPFPSTACIVQSNIGAKRAAAFDVSAACSGFLYGL
HHHHHHHCCCHHHEEEEEEEEECCCCCCCCCEEEEECCCCCCHHHHEEHHHHHHHHHHHH
SLADNAIRSGGASKALIIGAEVLSRVIDWTDRNTCLLFGDGSGAVVVEACESEQGVLSTH
HHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEEE
LHSDGSYWELLYQPGCGNRNPAVQKTLDERKNFLRMQGNEVFKLAVRAMEDAALQALEKN
ECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GLTPSDISIFIPHQANRRIIDAIGKRLGLSDDKVYVNLDRYGNTSSASIPLALDEANRGG
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCC
RINEGDIVLFDAFGGGLTWASVLLRW
CCCCCCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]