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The map label for this gene is bhbA [H]

Identifier: 78222784

GI number: 78222784

Start: 1774944

End: 1775348

Strand: Direct

Name: bhbA [H]

Synonym: Gmet_1574

Alternate gene names: 78222784

Gene position: 1774944-1775348 (Clockwise)

Preceding gene: 78222783

Following gene: 78222785

Centisome position: 44.4

GC content: 57.78

Gene sequence:

>405_bases
ATGACTGAAAGAACACTGCGTATTCTGGTGGGTAAACCCGGGCTCGACGGCCATGACCGTGGGGCGAAGATTATTGCCCG
AGCTTTCCGTGATGCCGGTTTTGAGGTCATTTATACGGGGCTCCATCAGACGCCGGAGCAGATCGTTTCCGCAGCCATTC
AAGAGGACGTTGACGCGGTTGGCTTGTCTATCCTCTCGGGTGCCCACAATGCGCTCCTGCCGCGGGTCTGCCAACTGCTC
AAGGAGAAGAAGGCTGACGATATCGTAGTTTTTGGCGGGGGCGTTATCCCCGATGACGATATTCCCGGGCTCAAACGGGC
TGGCGTCAGCGAGGTATTTACGCCGGGAACCTCAACTGAGTCCATTGTGCAGTGGGTGCGTGAAAACGTGGCCCCGCGCG
CATAG

Upstream 100 bases:

>100_bases
CGCTGCCGCTGATCTTGTTACTGAAATGCGGGAGATCAAGCATTACTATCGAGCCGGTGTTCCGGCTCGAGTCGGAATAG
AAAAGTAAGGGGAGAGAGTC

Downstream 100 bases:

>100_bases
TACGTTATCCCATGCCGTATAAAAAACTTCGTATCGAGATCCGCAATAAAGTCGGTTACATCCTGCTGTGTTCCGGCCAG
CGTTTCAATAAACTCAGCAT

Product: methylmalonyl-CoA mutase-like

Products: NA

Alternate protein names: MCM [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MTERTLRILVGKPGLDGHDRGAKIIARAFRDAGFEVIYTGLHQTPEQIVSAAIQEDVDAVGLSILSGAHNALLPRVCQLL
KEKKADDIVVFGGGVIPDDDIPGLKRAGVSEVFTPGTSTESIVQWVRENVAPRA

Sequences:

>Translated_134_residues
MTERTLRILVGKPGLDGHDRGAKIIARAFRDAGFEVIYTGLHQTPEQIVSAAIQEDVDAVGLSILSGAHNALLPRVCQLL
KEKKADDIVVFGGGVIPDDDIPGLKRAGVSEVFTPGTSTESIVQWVRENVAPRA
>Mature_133_residues
TERTLRILVGKPGLDGHDRGAKIIARAFRDAGFEVIYTGLHQTPEQIVSAAIQEDVDAVGLSILSGAHNALLPRVCQLLK
EKKADDIVVFGGGVIPDDDIPGLKRAGVSEVFTPGTSTESIVQWVRENVAPRA

Specific function: Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway [H]

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=114, Percent_Identity=48.2456140350877, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789284, Length=114, Percent_Identity=45.6140350877193, Blast_Score=104, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144500, Length=127, Percent_Identity=43.3070866141732, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: =5.4.99.2 [H]

Molecular weight: Translated: 14340; Mature: 14208

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERTLRILVGKPGLDGHDRGAKIIARAFRDAGFEVIYTGLHQTPEQIVSAAIQEDVDAV
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHEEHHCCCCCHHHHHHHHHHHHHHHH
GLSILSGAHNALLPRVCQLLKEKKADDIVVFGGGVIPDDDIPGLKRAGVSEVFTPGTSTE
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHCCCHHHCCCCCCHH
SIVQWVRENVAPRA
HHHHHHHHHCCCCC
>Mature Secondary Structure 
TERTLRILVGKPGLDGHDRGAKIIARAFRDAGFEVIYTGLHQTPEQIVSAAIQEDVDAV
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHEEHHCCCCCHHHHHHHHHHHHHHHH
GLSILSGAHNALLPRVCQLLKEKKADDIVVFGGGVIPDDDIPGLKRAGVSEVFTPGTSTE
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHCCCHHHCCCCCCHH
SIVQWVRENVAPRA
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9889346; 11481431 [H]