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The map label for this gene is tagO [H]

Identifier: 78222717

GI number: 78222717

Start: 1704425

End: 1706062

Strand: Direct

Name: tagO [H]

Synonym: Gmet_1505

Alternate gene names: 78222717

Gene position: 1704425-1706062 (Clockwise)

Preceding gene: 78222716

Following gene: 78222718

Centisome position: 42.64

GC content: 60.56

Gene sequence:

>1638_bases
ATGCTCCCCCTTGCGACCCTGATACTAGCGATGCTGCTGACGGTAATGCTCATCCCCGTGGTGAGCGCCCTGGCGGTGCG
CTTTCACGCCGTCGACATGCCCAATGAGCGCAAGGTGCACCTGCGGCCCATTCCACGGATCGGCGGCGTGGCCATGGCTC
TGGGCGCCTTTGTTCCGATTATGGTCTGGAACTTTGCCGACGGCTTCGTACGGGCCTATCTCATCGGCGCTTCGATCCTT
GTTGCCACCGGGCTCGTCGATGACCTGTATGAGCTGTCACCCCGCGTGAAATTCAGCGGTCAGTTCGCCGCGGCAGCGGT
GGCCCTCTTTATGGGTGGGGTAAAGATCGACAGCCTCGGGACACTCCTCCCCGAGAGCACAGCGCTTCCCGAACTTATCG
CTATCCCCCTCACCATTCTCGCCATCGTTGGCGTCACCAACGCGGTGAATATGGCCGACGGGCTCGACGGGCTCGCCGGC
GGCATCTGCCTCCTTATTTTTTGTGCAATCGGTTACCTGGCTTTTCTGGACGGCAACGTCTCCATCGGGCTTGTGGCCCT
GGCCATGGCCGGGGTCATTTTTGGGTTTCTTCGCTTCAACACCCACCCCGCCTCCATTTTCATGGGAGACGCGGGGAGCC
AGTTTCTCGGTTTTTCAGCGGTGACTCTGGCGCTGGGGCTCACCCAGGAGAGTGATTCCCTGAGTCCGCTCCTGCCGCTC
CTGCTCCTGGGGCTGCCGGTCCTCGATACGCTGACGGTCATGGCCATCAGGGCCTCCCAAGGGCGATCGATCTTCTCGGC
CGACAGAAACCATATCCATCACAGCCTCATGCAGATGGGGCTGCGGCATCCCGAGTCGGTGCTGGTCATTTACGTGGTCC
AGGCCCTGCTCGTGCTGGCGGCGGTGATGCTGCGCTTTCAGTCGGATGTGATCATTCTTGCGGGGTATCTGGGGTTCTCG
GTGGTTGTCGCGGGTTCTTTCGCCTATGCCCGCCGGACGGGCTTCACAATACGACGGTTTGACATCCTTGATGTGGTGAT
TGTGGGGGGGCTCAGGCGGGTCAAGGGGGAAGGTGGCGTTATCCGCCTGGCCTTCAGGTGTTTCGAGTTGGGTGTGCCGG
CACTACTCCTTGTCTCCTGCCTGCGCCCAGTGCGCGTTCCCGAATATGTATCCGTTGCGGCGCCCGCTTTACTCCTTCTG
CTGGCCCTTGTCCGCATTTTCCGGCCGGCGTGGAGCGGCGGCGCCATACGGGTAATCATCTATATCCTTGTTCCCTTTGT
GGTCTATTACGGCGACACCGGCGCCGGTTCACGGTTCGGGAGCATGGGAGAGCGGCTCTATGGAGTGATGTTCGGCATTC
TGGCGCTTCTTATCCCGGTCATCTCGAAGTTTTCGCGTCGCAGCGAGGGGTTTCGAAGCACTCCCCTCGATCTGCTTGTC
ATTATGCTCGCCGTGGCGGTTACGGGCCTTCCGGTCCAGTCTCTGCAACCCTACCGGCTCGGGCTCATGGCGGCAAAAAT
CATCATTCTCTATTTCGGATTTGAAGTGCTCATGGCCGAGTTGCGGGGCAAGTACGGACGGCTCTCCGGGTGGACAGCCG
CAGCTCTCGTTGCTCTGGTAACGATCAACTGGAGGTAA

Upstream 100 bases:

>100_bases
TGCGGAACGGATCTGGGATGTCATTGGCCGTAAATACGGGAAGGTGCCTGACTTGTCTGAGGCCTGCCATGAGCTTATGG
AGTGCGTGGGAAGCTGATTG

Downstream 100 bases:

>100_bases
TACAAAGATGAACCATCGTTCGGTACGTGGAATCTGCGCCACCCTCGGCGTCCTGCTTGTTATCGGCTGTAGCGGCCCCG
ACGCCAAGAAAGCCAAGTTC

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MLPLATLILAMLLTVMLIPVVSALAVRFHAVDMPNERKVHLRPIPRIGGVAMALGAFVPIMVWNFADGFVRAYLIGASIL
VATGLVDDLYELSPRVKFSGQFAAAAVALFMGGVKIDSLGTLLPESTALPELIAIPLTILAIVGVTNAVNMADGLDGLAG
GICLLIFCAIGYLAFLDGNVSIGLVALAMAGVIFGFLRFNTHPASIFMGDAGSQFLGFSAVTLALGLTQESDSLSPLLPL
LLLGLPVLDTLTVMAIRASQGRSIFSADRNHIHHSLMQMGLRHPESVLVIYVVQALLVLAAVMLRFQSDVIILAGYLGFS
VVVAGSFAYARRTGFTIRRFDILDVVIVGGLRRVKGEGGVIRLAFRCFELGVPALLLVSCLRPVRVPEYVSVAAPALLLL
LALVRIFRPAWSGGAIRVIIYILVPFVVYYGDTGAGSRFGSMGERLYGVMFGILALLIPVISKFSRRSEGFRSTPLDLLV
IMLAVAVTGLPVQSLQPYRLGLMAAKIIILYFGFEVLMAELRGKYGRLSGWTAAALVALVTINWR

Sequences:

>Translated_545_residues
MLPLATLILAMLLTVMLIPVVSALAVRFHAVDMPNERKVHLRPIPRIGGVAMALGAFVPIMVWNFADGFVRAYLIGASIL
VATGLVDDLYELSPRVKFSGQFAAAAVALFMGGVKIDSLGTLLPESTALPELIAIPLTILAIVGVTNAVNMADGLDGLAG
GICLLIFCAIGYLAFLDGNVSIGLVALAMAGVIFGFLRFNTHPASIFMGDAGSQFLGFSAVTLALGLTQESDSLSPLLPL
LLLGLPVLDTLTVMAIRASQGRSIFSADRNHIHHSLMQMGLRHPESVLVIYVVQALLVLAAVMLRFQSDVIILAGYLGFS
VVVAGSFAYARRTGFTIRRFDILDVVIVGGLRRVKGEGGVIRLAFRCFELGVPALLLVSCLRPVRVPEYVSVAAPALLLL
LALVRIFRPAWSGGAIRVIIYILVPFVVYYGDTGAGSRFGSMGERLYGVMFGILALLIPVISKFSRRSEGFRSTPLDLLV
IMLAVAVTGLPVQSLQPYRLGLMAAKIIILYFGFEVLMAELRGKYGRLSGWTAAALVALVTINWR
>Mature_545_residues
MLPLATLILAMLLTVMLIPVVSALAVRFHAVDMPNERKVHLRPIPRIGGVAMALGAFVPIMVWNFADGFVRAYLIGASIL
VATGLVDDLYELSPRVKFSGQFAAAAVALFMGGVKIDSLGTLLPESTALPELIAIPLTILAIVGVTNAVNMADGLDGLAG
GICLLIFCAIGYLAFLDGNVSIGLVALAMAGVIFGFLRFNTHPASIFMGDAGSQFLGFSAVTLALGLTQESDSLSPLLPL
LLLGLPVLDTLTVMAIRASQGRSIFSADRNHIHHSLMQMGLRHPESVLVIYVVQALLVLAAVMLRFQSDVIILAGYLGFS
VVVAGSFAYARRTGFTIRRFDILDVVIVGGLRRVKGEGGVIRLAFRCFELGVPALLLVSCLRPVRVPEYVSVAAPALLLL
LALVRIFRPAWSGGAIRVIIYILVPFVVYYGDTGAGSRFGSMGERLYGVMFGILALLIPVISKFSRRSEGFRSTPLDLLV
IMLAVAVTGLPVQSLQPYRLGLMAAKIIILYFGFEVLMAELRGKYGRLSGWTAAALVALVTINWR

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=265, Percent_Identity=32.0754716981132, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786275, Length=304, Percent_Identity=29.2763157894737, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 58326; Mature: 58326

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLATLILAMLLTVMLIPVVSALAVRFHAVDMPNERKVHLRPIPRIGGVAMALGAFVPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
MVWNFADGFVRAYLIGASILVATGLVDDLYELSPRVKFSGQFAAAAVALFMGGVKIDSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCEECHHH
TLLPESTALPELIAIPLTILAIVGVTNAVNMADGLDGLAGGICLLIFCAIGYLAFLDGNV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SIGLVALAMAGVIFGFLRFNTHPASIFMGDAGSQFLGFSAVTLALGLTQESDSLSPLLPL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLLGLPVLDTLTVMAIRASQGRSIFSADRNHIHHSLMQMGLRHPESVLVIYVVQALLVLA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVMLRFQSDVIILAGYLGFSVVVAGSFAYARRTGFTIRRFDILDVVIVGGLRRVKGEGGV
HHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHCCCEEEHHHHHHHHHHCCHHHCCCCCCE
IRLAFRCFELGVPALLLVSCLRPVRVPEYVSVAAPALLLLLALVRIFRPAWSGGAIRVII
EHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
YILVPFVVYYGDTGAGSRFGSMGERLYGVMFGILALLIPVISKFSRRSEGFRSTPLDLLV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IMLAVAVTGLPVQSLQPYRLGLMAAKIIILYFGFEVLMAELRGKYGRLSGWTAAALVALV
HHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TINWR
HCCCC
>Mature Secondary Structure
MLPLATLILAMLLTVMLIPVVSALAVRFHAVDMPNERKVHLRPIPRIGGVAMALGAFVPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
MVWNFADGFVRAYLIGASILVATGLVDDLYELSPRVKFSGQFAAAAVALFMGGVKIDSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCEECHHH
TLLPESTALPELIAIPLTILAIVGVTNAVNMADGLDGLAGGICLLIFCAIGYLAFLDGNV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
SIGLVALAMAGVIFGFLRFNTHPASIFMGDAGSQFLGFSAVTLALGLTQESDSLSPLLPL
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLLGLPVLDTLTVMAIRASQGRSIFSADRNHIHHSLMQMGLRHPESVLVIYVVQALLVLA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVMLRFQSDVIILAGYLGFSVVVAGSFAYARRTGFTIRRFDILDVVIVGGLRRVKGEGGV
HHHHHHCCCCEEEEHHHHHHHHHHCCHHHHHHCCCEEEHHHHHHHHHHCCHHHCCCCCCE
IRLAFRCFELGVPALLLVSCLRPVRVPEYVSVAAPALLLLLALVRIFRPAWSGGAIRVII
EHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
YILVPFVVYYGDTGAGSRFGSMGERLYGVMFGILALLIPVISKFSRRSEGFRSTPLDLLV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IMLAVAVTGLPVQSLQPYRLGLMAAKIIILYFGFEVLMAELRGKYGRLSGWTAAALVALV
HHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TINWR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]