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The map label for this gene is wecB [H]

Identifier: 78222716

GI number: 78222716

Start: 1703273

End: 1704421

Strand: Direct

Name: wecB [H]

Synonym: Gmet_1504

Alternate gene names: 78222716

Gene position: 1703273-1704421 (Clockwise)

Preceding gene: 78222715

Following gene: 78222717

Centisome position: 42.61

GC content: 60.05

Gene sequence:

>1149_bases
ATGAACGTCTTTCTCGTGGCCGGAGCCCGGCCAAATTTCATGAAGATCGCACCGCTGTATCGCGAATCCCTCACCCGTGA
GGGGGTGACCTGCCGCATCGTCCACACGGGGCAGCACTATGACTACGAGATGTCCCAGACGTTCTTCGACGACCTGCAAC
TCCCCCAGCCCGACTACTTCCTCAATGCCGGTTCCGGCTCCCACGCCGAGCAGACAGCCCGGGTCATGGTGACTTTCGAG
GAGCTGTGTGCAAAGGAACTCCCTGATCTGGTGATCGTCGTGGGGGATGTGAATTCGACCCTCGCCTGCAGCATTGTGGC
GAAGAAGGCTGGTATCCGGGTGGCCCACGTGGAGGCGGGGCTCCGCAGCTTCGACCTCTCCATGCCCGAGGAGATCAACC
GGATGGTGACCGACTCCATCGCCGACCTCTACTTCGTCACCGAAACGAGCGCTGTCCGCAACCTCTTTAACGAAGGAAAA
CCGCCGGAGCAGATCTTTCTGGTGGGACACGTCATGGTCGACAATCTCCTTCACCAGATGGTTCAGGTTCACCTGAACGG
GGCTGTGGCGCCCGAACTGCGGGAATTGAAGCAGAAGGCGGGAGAGTACGTGTTCATGACCCTTCATCGCCCCTCTAATG
TTGATGACGAGGAGACCTTCCGCGGCATCGCCTTTGCCGTGAACGAGATTGCGGCCCGGATACCGATTATCTTCCCCGTT
CACCCGCGGACCCGCAAGATGATGGAGAGCTTTGGCATCCAGCTCCACAAGGGTGTCACCTGTCTTCCACCCCTGAGTTT
CAGTGAGTCCCTCTATTTCTGGAAGGATGCCCGGGTGGTCATGACCGACAGCGGCGGCCTCCAGGAGGAAACCACAGCCC
TGGGGGTCCCCTGCGTCACTATCAGGGAGAACACCGAGCGTCCCATTACCGTGGAAATGGGGACCAACGTCCTGGCCGGG
ACCGACCCGGATCGGATTCTTACCCGCGTTTTCGATGCGGCGGAGGGAAGGGGCAAGCGGGGGAAGGTTCCCCCCTTCTG
GGACGGCAAGGCTGCGGAACGGATCTGGGATGTCATTGGCCGTAAATACGGGAAGGTGCCTGACTTGTCTGAGGCCTGCC
ATGAGCTTATGGAGTGCGTGGGAAGCTGA

Upstream 100 bases:

>100_bases
TGGATTTCTTCCTGGGGCCTAGCAATCCATTGTCCCTGACCATTGCCGGACTCCTCACGGAAGAACCGGCCTACACCAAC
TGATTTCGAGGAGTACCCCC

Downstream 100 bases:

>100_bases
TTGATGCTCCCCCTTGCGACCCTGATACTAGCGATGCTGCTGACGGTAATGCTCATCCCCGTGGTGAGCGCCCTGGCGGT
GCGCTTTCACGCCGTCGACA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNVFLVAGARPNFMKIAPLYRESLTREGVTCRIVHTGQHYDYEMSQTFFDDLQLPQPDYFLNAGSGSHAEQTARVMVTFE
ELCAKELPDLVIVVGDVNSTLACSIVAKKAGIRVAHVEAGLRSFDLSMPEEINRMVTDSIADLYFVTETSAVRNLFNEGK
PPEQIFLVGHVMVDNLLHQMVQVHLNGAVAPELRELKQKAGEYVFMTLHRPSNVDDEETFRGIAFAVNEIAARIPIIFPV
HPRTRKMMESFGIQLHKGVTCLPPLSFSESLYFWKDARVVMTDSGGLQEETTALGVPCVTIRENTERPITVEMGTNVLAG
TDPDRILTRVFDAAEGRGKRGKVPPFWDGKAAERIWDVIGRKYGKVPDLSEACHELMECVGS

Sequences:

>Translated_382_residues
MNVFLVAGARPNFMKIAPLYRESLTREGVTCRIVHTGQHYDYEMSQTFFDDLQLPQPDYFLNAGSGSHAEQTARVMVTFE
ELCAKELPDLVIVVGDVNSTLACSIVAKKAGIRVAHVEAGLRSFDLSMPEEINRMVTDSIADLYFVTETSAVRNLFNEGK
PPEQIFLVGHVMVDNLLHQMVQVHLNGAVAPELRELKQKAGEYVFMTLHRPSNVDDEETFRGIAFAVNEIAARIPIIFPV
HPRTRKMMESFGIQLHKGVTCLPPLSFSESLYFWKDARVVMTDSGGLQEETTALGVPCVTIRENTERPITVEMGTNVLAG
TDPDRILTRVFDAAEGRGKRGKVPPFWDGKAAERIWDVIGRKYGKVPDLSEACHELMECVGS
>Mature_382_residues
MNVFLVAGARPNFMKIAPLYRESLTREGVTCRIVHTGQHYDYEMSQTFFDDLQLPQPDYFLNAGSGSHAEQTARVMVTFE
ELCAKELPDLVIVVGDVNSTLACSIVAKKAGIRVAHVEAGLRSFDLSMPEEINRMVTDSIADLYFVTETSAVRNLFNEGK
PPEQIFLVGHVMVDNLLHQMVQVHLNGAVAPELRELKQKAGEYVFMTLHRPSNVDDEETFRGIAFAVNEIAARIPIIFPV
HPRTRKMMESFGIQLHKGVTCLPPLSFSESLYFWKDARVVMTDSGGLQEETTALGVPCVTIRENTERPITVEMGTNVLAG
TDPDRILTRVFDAAEGRGKRGKVPPFWDGKAAERIWDVIGRKYGKVPDLSEACHELMECVGS

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=376, Percent_Identity=32.7127659574468, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42573; Mature: 42573

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFLVAGARPNFMKIAPLYRESLTREGVTCRIVHTGQHYDYEMSQTFFDDLQLPQPDYF
CEEEEEECCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEE
LNAGSGSHAEQTARVMVTFEELCAKELPDLVIVVGDVNSTLACSIVAKKAGIRVAHVEAG
EECCCCCCHHHHHHHEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHCCCEEEEECCC
LRSFDLSMPEEINRMVTDSIADLYFVTETSAVRNLFNEGKPPEQIFLVGHVMVDNLLHQM
HHHCCCCCHHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHH
VQVHLNGAVAPELRELKQKAGEYVFMTLHRPSNVDDEETFRGIAFAVNEIAARIPIIFPV
HHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEC
HPRTRKMMESFGIQLHKGVTCLPPLSFSESLYFWKDARVVMTDSGGLQEETTALGVPCVT
CHHHHHHHHHCCCEEECCEEECCCCCCCCCEEEEECCEEEEECCCCCCCCHHHCCCCEEE
IRENTERPITVEMGTNVLAGTDPDRILTRVFDAAEGRGKRGKVPPFWDGKAAERIWDVIG
EECCCCCCEEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
RKYGKVPDLSEACHELMECVGS
HHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVFLVAGARPNFMKIAPLYRESLTREGVTCRIVHTGQHYDYEMSQTFFDDLQLPQPDYF
CEEEEEECCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEE
LNAGSGSHAEQTARVMVTFEELCAKELPDLVIVVGDVNSTLACSIVAKKAGIRVAHVEAG
EECCCCCCHHHHHHHEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHCCCEEEEECCC
LRSFDLSMPEEINRMVTDSIADLYFVTETSAVRNLFNEGKPPEQIFLVGHVMVDNLLHQM
HHHCCCCCHHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHH
VQVHLNGAVAPELRELKQKAGEYVFMTLHRPSNVDDEETFRGIAFAVNEIAARIPIIFPV
HHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEC
HPRTRKMMESFGIQLHKGVTCLPPLSFSESLYFWKDARVVMTDSGGLQEETTALGVPCVT
CHHHHHHHHHCCCEEECCEEECCCCCCCCCEEEEECCEEEEECCCCCCCCHHHCCCCEEE
IRENTERPITVEMGTNVLAGTDPDRILTRVFDAAEGRGKRGKVPPFWDGKAAERIWDVIG
EECCCCCCEEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
RKYGKVPDLSEACHELMECVGS
HHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA