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The map label for this gene is rsbU [H]

Identifier: 78222684

GI number: 78222684

Start: 1654569

End: 1655783

Strand: Reverse

Name: rsbU [H]

Synonym: Gmet_1472

Alternate gene names: 78222684

Gene position: 1655783-1654569 (Counterclockwise)

Preceding gene: 78222691

Following gene: 78222683

Centisome position: 41.42

GC content: 55.14

Gene sequence:

>1215_bases
ATGACGGATTATTGTGAGAGCAGTGTACCGATTTTGCGGGACATCGCGGTGCCGAATGCCGGAGTCTCCCCGAACGTAAC
GGTGCGCGAAGTTGTGGAAATTTTTCAGGGCGATGCAACGCTGCTCACGCTGCCGATTATTGACGAAGGTGAGTTCCTGG
GAATCATCAACCGCAAGGTTCTGATTTTCAAACACCTCGGCCGACCTTTTACCATGGAACTCTACGGGAAGAAACCGATC
AGGGAACTTCTTGATGAGTGTCCGTTTACCATGAATGCGGGAGTCGACGTAAACAGCGCCCTCGAACGGCTTATCGAGGT
GGATCCGAGACTGGAAACCGATTCGTTTCCGGTCATGGATGGAAAATGCTGCATCGGCATCGCCTCGGTGGCGGAACTCA
TGATGAGCATATCCAGAACCCAGGCTGCTCTCTTGCAGACCCTCAATCGGCTTACCGCCCGCATAAGAGCGGAGGTCGAC
AATGCGAGGAGTATCCAGCAGGATCTCCTTCCCCTCGATTCAGCGCGGTTCAACAACATTGCAATCTCTGCAAGCATGAC
CACATCCACAGAGATCGGAGGAGATTTTTACGATTACATCCGACTCCCCGATTCAACGGTCTGCATCGTCATGGGTGATG
TGAGCGGCCACGGAATCCAGGCCGGGATGGTAACCACCGCGGCCAAGGCGAGCCTTCACACCCTTATCGCAGCAGGCGCC
ACCACGCCGGCTCGGCTCTTGTCCGGCATGAACAACGCCATTCTGGCCACTGCCCGTCAAAACCTTCTCATGACGTGCGT
CGTTATCAGCATAAATCAGCAGCAGCGGATAGCCACCATCGCAAATGCCGGTCATACCTTTCCCTATCTTTACCGCACAA
TTCCTACGTACATGGAGCGCATCGAGGTGGTTTCCGGGTTTCCCCTCGGATTTGAACGCGACGGAGGCTACACGGAACTG
ACCATTCCCTTCCGTGAGGGAGACAGACTCATTGTCTATACCGATGGGATAGTGGAAGCCACCGATAGCGCCGGCCGCCA
GTTCGGATATGAACGGTTCGAGGCTGTTTTTCTCGAACATCGGGAACTCTCGTCCGACCAGCTGAAAGAGCAGCTCTTCA
CGGACATTCACTCGTTTGCCGCCAGCGAAGCCCTCGATGACGATGTCGCACTCCTGATCGCCTCGTTCGACGGTTGTGCC
CCTGAGGTACCATGA

Upstream 100 bases:

>100_bases
TTGTAACGTGACCATCACATTTGCTGCCGATAGTAATTAATGAGACAGCAGTTGCAGCGCTATGCTCTGATGACCCAGCG
GTTTTGAGAACGGATAAATC

Downstream 100 bases:

>100_bases
GCATGAACACCCCATCCCTTGCTTTTTTCAGAAATGATGCCGACGAACGGCTTTGGAAGGCCGACCTGGAAGCCATCCCC
GGAATGATCTCTATCGTGAC

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTDYCESSVPILRDIAVPNAGVSPNVTVREVVEIFQGDATLLTLPIIDEGEFLGIINRKVLIFKHLGRPFTMELYGKKPI
RELLDECPFTMNAGVDVNSALERLIEVDPRLETDSFPVMDGKCCIGIASVAELMMSISRTQAALLQTLNRLTARIRAEVD
NARSIQQDLLPLDSARFNNIAISASMTTSTEIGGDFYDYIRLPDSTVCIVMGDVSGHGIQAGMVTTAAKASLHTLIAAGA
TTPARLLSGMNNAILATARQNLLMTCVVISINQQQRIATIANAGHTFPYLYRTIPTYMERIEVVSGFPLGFERDGGYTEL
TIPFREGDRLIVYTDGIVEATDSAGRQFGYERFEAVFLEHRELSSDQLKEQLFTDIHSFAASEALDDDVALLIASFDGCA
PEVP

Sequences:

>Translated_404_residues
MTDYCESSVPILRDIAVPNAGVSPNVTVREVVEIFQGDATLLTLPIIDEGEFLGIINRKVLIFKHLGRPFTMELYGKKPI
RELLDECPFTMNAGVDVNSALERLIEVDPRLETDSFPVMDGKCCIGIASVAELMMSISRTQAALLQTLNRLTARIRAEVD
NARSIQQDLLPLDSARFNNIAISASMTTSTEIGGDFYDYIRLPDSTVCIVMGDVSGHGIQAGMVTTAAKASLHTLIAAGA
TTPARLLSGMNNAILATARQNLLMTCVVISINQQQRIATIANAGHTFPYLYRTIPTYMERIEVVSGFPLGFERDGGYTEL
TIPFREGDRLIVYTDGIVEATDSAGRQFGYERFEAVFLEHRELSSDQLKEQLFTDIHSFAASEALDDDVALLIASFDGCA
PEVP
>Mature_403_residues
TDYCESSVPILRDIAVPNAGVSPNVTVREVVEIFQGDATLLTLPIIDEGEFLGIINRKVLIFKHLGRPFTMELYGKKPIR
ELLDECPFTMNAGVDVNSALERLIEVDPRLETDSFPVMDGKCCIGIASVAELMMSISRTQAALLQTLNRLTARIRAEVDN
ARSIQQDLLPLDSARFNNIAISASMTTSTEIGGDFYDYIRLPDSTVCIVMGDVSGHGIQAGMVTTAAKASLHTLIAAGAT
TPARLLSGMNNAILATARQNLLMTCVVISINQQQRIATIANAGHTFPYLYRTIPTYMERIEVVSGFPLGFERDGGYTELT
IPFREGDRLIVYTDGIVEATDSAGRQFGYERFEAVFLEHRELSSDQLKEQLFTDIHSFAASEALDDDVALLIASFDGCAP
EVP

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 44212; Mature: 44081

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYCESSVPILRDIAVPNAGVSPNVTVREVVEIFQGDATLLTLPIIDEGEFLGIINRKV
CCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEECCEE
LIFKHLGRPFTMELYGKKPIRELLDECPFTMNAGVDVNSALERLIEVDPRLETDSFPVMD
EEEHHCCCCEEEEECCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC
GKCCIGIASVAELMMSISRTQAALLQTLNRLTARIRAEVDNARSIQQDLLPLDSARFNNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AISASMTTSTEIGGDFYDYIRLPDSTVCIVMGDVSGHGIQAGMVTTAAKASLHTLIAAGA
EEEEECCCCCCCCCCHHHHEECCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCC
TTPARLLSGMNNAILATARQNLLMTCVVISINQQQRIATIANAGHTFPYLYRTIPTYMER
CCHHHHHCCCCCCEEHHHHHHHEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IEVVSGFPLGFERDGGYTELTIPFREGDRLIVYTDGIVEATDSAGRQFGYERFEAVFLEH
HHHHCCCCCCEECCCCEEEEEEEEECCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHH
RELSSDQLKEQLFTDIHSFAASEALDDDVALLIASFDGCAPEVP
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TDYCESSVPILRDIAVPNAGVSPNVTVREVVEIFQGDATLLTLPIIDEGEFLGIINRKV
CCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEECCEE
LIFKHLGRPFTMELYGKKPIRELLDECPFTMNAGVDVNSALERLIEVDPRLETDSFPVMD
EEEHHCCCCEEEEECCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC
GKCCIGIASVAELMMSISRTQAALLQTLNRLTARIRAEVDNARSIQQDLLPLDSARFNNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AISASMTTSTEIGGDFYDYIRLPDSTVCIVMGDVSGHGIQAGMVTTAAKASLHTLIAAGA
EEEEECCCCCCCCCCHHHHEECCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCC
TTPARLLSGMNNAILATARQNLLMTCVVISINQQQRIATIANAGHTFPYLYRTIPTYMER
CCHHHHHCCCCCCEEHHHHHHHEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHH
IEVVSGFPLGFERDGGYTELTIPFREGDRLIVYTDGIVEATDSAGRQFGYERFEAVFLEH
HHHHCCCCCCEECCCCEEEEEEEEECCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHH
RELSSDQLKEQLFTDIHSFAASEALDDDVALLIASFDGCAPEVP
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]