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The map label for this gene is cheA [H]

Identifier: 78222298

GI number: 78222298

Start: 1201507

End: 1203555

Strand: Reverse

Name: cheA [H]

Synonym: Gmet_1080

Alternate gene names: 78222298

Gene position: 1203555-1201507 (Counterclockwise)

Preceding gene: 78222299

Following gene: 78222297

Centisome position: 30.11

GC content: 65.01

Gene sequence:

>2049_bases
ATGACCGCCCCGGATCACCACAACACCTCCATCGACCTCGATCGCTTCAACGCCGTCTTTTTCGAGGAATGCGCCGAGCA
CCTGGCCGATATGGAGCACATCCTCGTGGCCCTCGACCCGGAGAGCCCCGACAGTGAGGAACTGAACGCCCTGTTCCGCG
CGGCCCACTCCATCAAGGGAGGGGCCGGCATTTTCGGCTTCAGTGACCTTACCGTGGTAACCCACGAGCTTGAATCGCTC
CTGGACAAGGTGCGCGGCAACGAACTCCGCCTGACCGCCACCATGATCGACCTGTTCCTGGAGGCCCGCGACGCCATTGC
CATGCAGCTGGCGGGGCACGGGGACGGCAGCCCTGTTGACCAGGCGGTTATCGAGGATATCTGCCGCAGACTTCGCGGCC
AGATCGAAGGAACTGCTGCAGTTGCCGAAAAGTCCCCTTCGCCCCAGGTCCTGCCCACCGAACCCATGACCGGCTTCCGA
CGGTTGGAGATCGTCTTTTCCCCCGACAACGATATCTTCCAGCGGGGCGTGCGGCTCGAAAACCTCTTCAACGAACTGGC
GCAGCTGGGGGACCTCTCGGTGAAGGCAGAGATCCCTGATGCCCCCCCCTTTGAGGCATTCGATCCCGAGGTCTGCCACG
CCCGGTGGATTTTCACCCTCGACACGGTCGTCGCCGATGAGGAGATCCGGGACATCTTCGAGTTCGTGGCCGAACGGGAG
CAGCTGACGATCAGCACCAGGGACGAGCAGGCAACCGCCGCGCCATCACCCGTAGAAGAAGACATCCCTGCCCCCGCCAG
CGCGCCGGCAGAGGGAGCCATCGTCCCCATGGGGCGCCGCGCCTACGACCGCGATGAAACGGCGCCCGGAGCCTTCGGCC
GCCGGGGGGGCGAAATCGAGTCGTCAATCCGTGTGGGAGTGACCAAGGTGGACCAGCTCATCAACCAGGTGGGCGAACTG
GTCATCACCCAGTCCATGCTGGCCCAGATGGCAGGAGTGCTCGATCCGGTCCTCTTCGAGAGCATTCACCGGGGGCTCCT
GCAACTGGAGCGCAACACCCGCGATCTCCAGCAGAATGTCATGTCGATCCGGCTGGTCCCCATCAGCATCGTCTTCAGCC
GTTTCCCGCGCCTGGTGCGCGACCTGGCAGCCAAGCTCGGCAAGCAGGTGGAGCTGCACACCGTGGGGGAGACCACCGAA
CTGGACAAGGGGCTCATCGAGAAGATTGCCGATCCCCTCACCCATCTGGTGCGGAACTGCCTCGACCACGGGCTCGAATC
CCCCGAGGCGCGCATGGCCGCAGGGAAGGATCCCGTCGGCGCCATAATGCTGCGGGCCTCCCAGGTGGGGGGACGGATCG
TCATCGATGTCATGGACGACGGCGCCGGCCTCAGCCGGGAGAAGATTCTCCGCAAGGCGGCCGAACGGGGCATCCCGACC
GGCGACGCCATGACCGACGAGGAGGTCTGGCAGCTGATCTTCGCCCCCGGCTTCTCCACCGCCGAAACCGTGACCGACAT
CTCCGGCCGCGGGGTCGGCATGGACGTGGTGCTGCGGAACGTGCAGGCCCTGAGCGGACGGGTGCAGGTCTCGTCGGAGC
CGGGCTCCGGAACCCGCGTCACCATCAGCCTCCCCCTGACCCTGGCGATCCTCGATGGCCTCTCCGTGGCGGTGGGGGGC
GAGAAGTTCATCATCCCCCTGAACGCCATCATCGAATCCCTCCAGCCGAAGCCGGAGGAGATCAAGTCGGTCAACGGCAG
GACCGTCGTCCACGTGCGGGGGGAATACCTCCCCCTTCTGCCGCTCCACGAACTCTTCAGCCTGGAGACATCGGTCACGC
GGCCCGAAGAGGGAATCACCGTACTGGTGGATGTGGAAGGAGAGAAGGCGGCGCTGTTGGTGGACGCCCTCCTGGACGAG
CACCAAGTGGTCATCAAGAGCCTTGAGGCCAACTACCGCAAGGTTGAGGGAACGGCGGGCGCGACAATCCTCGGGGACGG
GCGGGTGGCGCTGATCCTGGACGTCCATGCCCTGCTCCGGATGAGATAA

Upstream 100 bases:

>100_bases
CCGTTCTGGCCAATATCCCGGCAGAACTCCGCGGCAGCATCGAGCTCCTCGGCTTCGGCCACGAATTCGAGACGATGCTT
GACGTCACCAGAGGACACGC

Downstream 100 bases:

>100_bases
ATACAGTCAGGAGGATATACACAACTATGGATACGCCTGAAAGAACCATCCCCCATGAATACCTCACCTTCACCCTCGGA
GCAGAGGAGTACGGCATCGA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MTAPDHHNTSIDLDRFNAVFFEECAEHLADMEHILVALDPESPDSEELNALFRAAHSIKGGAGIFGFSDLTVVTHELESL
LDKVRGNELRLTATMIDLFLEARDAIAMQLAGHGDGSPVDQAVIEDICRRLRGQIEGTAAVAEKSPSPQVLPTEPMTGFR
RLEIVFSPDNDIFQRGVRLENLFNELAQLGDLSVKAEIPDAPPFEAFDPEVCHARWIFTLDTVVADEEIRDIFEFVAERE
QLTISTRDEQATAAPSPVEEDIPAPASAPAEGAIVPMGRRAYDRDETAPGAFGRRGGEIESSIRVGVTKVDQLINQVGEL
VITQSMLAQMAGVLDPVLFESIHRGLLQLERNTRDLQQNVMSIRLVPISIVFSRFPRLVRDLAAKLGKQVELHTVGETTE
LDKGLIEKIADPLTHLVRNCLDHGLESPEARMAAGKDPVGAIMLRASQVGGRIVIDVMDDGAGLSREKILRKAAERGIPT
GDAMTDEEVWQLIFAPGFSTAETVTDISGRGVGMDVVLRNVQALSGRVQVSSEPGSGTRVTISLPLTLAILDGLSVAVGG
EKFIIPLNAIIESLQPKPEEIKSVNGRTVVHVRGEYLPLLPLHELFSLETSVTRPEEGITVLVDVEGEKAALLVDALLDE
HQVVIKSLEANYRKVEGTAGATILGDGRVALILDVHALLRMR

Sequences:

>Translated_682_residues
MTAPDHHNTSIDLDRFNAVFFEECAEHLADMEHILVALDPESPDSEELNALFRAAHSIKGGAGIFGFSDLTVVTHELESL
LDKVRGNELRLTATMIDLFLEARDAIAMQLAGHGDGSPVDQAVIEDICRRLRGQIEGTAAVAEKSPSPQVLPTEPMTGFR
RLEIVFSPDNDIFQRGVRLENLFNELAQLGDLSVKAEIPDAPPFEAFDPEVCHARWIFTLDTVVADEEIRDIFEFVAERE
QLTISTRDEQATAAPSPVEEDIPAPASAPAEGAIVPMGRRAYDRDETAPGAFGRRGGEIESSIRVGVTKVDQLINQVGEL
VITQSMLAQMAGVLDPVLFESIHRGLLQLERNTRDLQQNVMSIRLVPISIVFSRFPRLVRDLAAKLGKQVELHTVGETTE
LDKGLIEKIADPLTHLVRNCLDHGLESPEARMAAGKDPVGAIMLRASQVGGRIVIDVMDDGAGLSREKILRKAAERGIPT
GDAMTDEEVWQLIFAPGFSTAETVTDISGRGVGMDVVLRNVQALSGRVQVSSEPGSGTRVTISLPLTLAILDGLSVAVGG
EKFIIPLNAIIESLQPKPEEIKSVNGRTVVHVRGEYLPLLPLHELFSLETSVTRPEEGITVLVDVEGEKAALLVDALLDE
HQVVIKSLEANYRKVEGTAGATILGDGRVALILDVHALLRMR
>Mature_681_residues
TAPDHHNTSIDLDRFNAVFFEECAEHLADMEHILVALDPESPDSEELNALFRAAHSIKGGAGIFGFSDLTVVTHELESLL
DKVRGNELRLTATMIDLFLEARDAIAMQLAGHGDGSPVDQAVIEDICRRLRGQIEGTAAVAEKSPSPQVLPTEPMTGFRR
LEIVFSPDNDIFQRGVRLENLFNELAQLGDLSVKAEIPDAPPFEAFDPEVCHARWIFTLDTVVADEEIRDIFEFVAEREQ
LTISTRDEQATAAPSPVEEDIPAPASAPAEGAIVPMGRRAYDRDETAPGAFGRRGGEIESSIRVGVTKVDQLINQVGELV
ITQSMLAQMAGVLDPVLFESIHRGLLQLERNTRDLQQNVMSIRLVPISIVFSRFPRLVRDLAAKLGKQVELHTVGETTEL
DKGLIEKIADPLTHLVRNCLDHGLESPEARMAAGKDPVGAIMLRASQVGGRIVIDVMDDGAGLSREKILRKAAERGIPTG
DAMTDEEVWQLIFAPGFSTAETVTDISGRGVGMDVVLRNVQALSGRVQVSSEPGSGTRVTISLPLTLAILDGLSVAVGGE
KFIIPLNAIIESLQPKPEEIKSVNGRTVVHVRGEYLPLLPLHELFSLETSVTRPEEGITVLVDVEGEKAALLVDALLDEH
QVVIKSLEANYRKVEGTAGATILGDGRVALILDVHALLRMR

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=679, Percent_Identity=49.0427098674521, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74136; Mature: 74004

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPDHHNTSIDLDRFNAVFFEECAEHLADMEHILVALDPESPDSEELNALFRAAHSIKG
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCHHHHHHHHHHHHHCCC
GAGIFGFSDLTVVTHELESLLDKVRGNELRLTATMIDLFLEARDAIAMQLAGHGDGSPVD
CCCEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHEEEEECCCCCCHHH
QAVIEDICRRLRGQIEGTAAVAEKSPSPQVLPTEPMTGFRRLEIVFSPDNDIFQRGVRLE
HHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHCCHHH
NLFNELAQLGDLSVKAEIPDAPPFEAFDPEVCHARWIFTLDTVVADEEIRDIFEFVAERE
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHHCCH
QLTISTRDEQATAAPSPVEEDIPAPASAPAEGAIVPMGRRAYDRDETAPGAFGRRGGEIE
HEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
SSIRVGVTKVDQLINQVGELVITQSMLAQMAGVLDPVLFESIHRGLLQLERNTRDLQQNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSIRLVPISIVFSRFPRLVRDLAAKLGKQVELHTVGETTELDKGLIEKIADPLTHLVRNC
HEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LDHGLESPEARMAAGKDPVGAIMLRASQVGGRIVIDVMDDGAGLSREKILRKAAERGIPT
HHCCCCCCHHHHHCCCCCHHHHEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC
GDAMTDEEVWQLIFAPGFSTAETVTDISGRGVGMDVVLRNVQALSGRVQVSSEPGSGTRV
CCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEE
TISLPLTLAILDGLSVAVGGEKFIIPLNAIIESLQPKPEEIKSVNGRTVVHVRGEYLPLL
EEECCHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCC
PLHELFSLETSVTRPEEGITVLVDVEGEKAALLVDALLDEHQVVIKSLEANYRKVEGTAG
CHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
ATILGDGRVALILDVHALLRMR
CEEECCCCEEEEEEHHHHHHCC
>Mature Secondary Structure 
TAPDHHNTSIDLDRFNAVFFEECAEHLADMEHILVALDPESPDSEELNALFRAAHSIKG
CCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHEEEEEECCCCCCHHHHHHHHHHHHHCCC
GAGIFGFSDLTVVTHELESLLDKVRGNELRLTATMIDLFLEARDAIAMQLAGHGDGSPVD
CCCEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHEEEEECCCCCCHHH
QAVIEDICRRLRGQIEGTAAVAEKSPSPQVLPTEPMTGFRRLEIVFSPDNDIFQRGVRLE
HHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHCCHHH
NLFNELAQLGDLSVKAEIPDAPPFEAFDPEVCHARWIFTLDTVVADEEIRDIFEFVAERE
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHHCCH
QLTISTRDEQATAAPSPVEEDIPAPASAPAEGAIVPMGRRAYDRDETAPGAFGRRGGEIE
HEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
SSIRVGVTKVDQLINQVGELVITQSMLAQMAGVLDPVLFESIHRGLLQLERNTRDLQQNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSIRLVPISIVFSRFPRLVRDLAAKLGKQVELHTVGETTELDKGLIEKIADPLTHLVRNC
HEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LDHGLESPEARMAAGKDPVGAIMLRASQVGGRIVIDVMDDGAGLSREKILRKAAERGIPT
HHCCCCCCHHHHHCCCCCHHHHEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCC
GDAMTDEEVWQLIFAPGFSTAETVTDISGRGVGMDVVLRNVQALSGRVQVSSEPGSGTRV
CCCCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCEE
TISLPLTLAILDGLSVAVGGEKFIIPLNAIIESLQPKPEEIKSVNGRTVVHVRGEYLPLL
EEECCHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCC
PLHELFSLETSVTRPEEGITVLVDVEGEKAALLVDALLDEHQVVIKSLEANYRKVEGTAG
CHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
ATILGDGRVALILDVHALLRMR
CEEECCCCEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]