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The map label for this gene is cheW [H]

Identifier: 78222297

GI number: 78222297

Start: 1201010

End: 1201480

Strand: Reverse

Name: cheW [H]

Synonym: Gmet_1079

Alternate gene names: 78222297

Gene position: 1201480-1201010 (Counterclockwise)

Preceding gene: 78222298

Following gene: 78222296

Centisome position: 30.06

GC content: 60.93

Gene sequence:

>471_bases
ATGGATACGCCTGAAAGAACCATCCCCCATGAATACCTCACCTTCACCCTCGGAGCAGAGGAGTACGGCATCGATATCCT
GAAGGTGCAGGAGATCCGGGGCTATGACGCCGTAACCCGCATCGCCAACTCCCCCGAATTCCTCAAGGGGGTCATCAACC
TGCGGGGGGTTATCGTCCCCATCGTCGACATGCGGATCAGATTCAACCTCGGCACCCCCACCTACGACGAATTCACCGTG
GTCATCATCATGAACGTGCTGAACCGGGTCATCGGCATGGTGGTGGACGGCGTCTCCGACGTGGTGGCCCTGGAGCCGGA
GCAGATCAGGCCGGCCCCGGAGATGGGGTCGGCCCTGGATACCCGCTACCTGACCGGCCTCGGCACCGTGAACGGCCAGA
TGCTCATCCTCATGGACATCGAGAAGCTCCTGAGCAGCAGCGAGATGCAGCTCATGGACAGTGCAGCCTGA

Upstream 100 bases:

>100_bases
CGGGCGCGACAATCCTCGGGGACGGGCGGGTGGCGCTGATCCTGGACGTCCATGCCCTGCTCCGGATGAGATAAATACAG
TCAGGAGGATATACACAACT

Downstream 100 bases:

>100_bases
TCAAGAATCCTCAAAGGAAGGTGAACCTATGAAAATCAAAGCATTCAAAGACTGGAAGATTCTCTCCAAAATCCTCGCCA
TCTCGGTGGCAACCATCGTG

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MDTPERTIPHEYLTFTLGAEEYGIDILKVQEIRGYDAVTRIANSPEFLKGVINLRGVIVPIVDMRIRFNLGTPTYDEFTV
VIIMNVLNRVIGMVVDGVSDVVALEPEQIRPAPEMGSALDTRYLTGLGTVNGQMLILMDIEKLLSSSEMQLMDSAA

Sequences:

>Translated_156_residues
MDTPERTIPHEYLTFTLGAEEYGIDILKVQEIRGYDAVTRIANSPEFLKGVINLRGVIVPIVDMRIRFNLGTPTYDEFTV
VIIMNVLNRVIGMVVDGVSDVVALEPEQIRPAPEMGSALDTRYLTGLGTVNGQMLILMDIEKLLSSSEMQLMDSAA
>Mature_156_residues
MDTPERTIPHEYLTFTLGAEEYGIDILKVQEIRGYDAVTRIANSPEFLKGVINLRGVIVPIVDMRIRFNLGTPTYDEFTV
VIIMNVLNRVIGMVVDGVSDVVALEPEQIRPAPEMGSALDTRYLTGLGTVNGQMLILMDIEKLLSSSEMQLMDSAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=147, Percent_Identity=67.3469387755102, Blast_Score=199, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17274; Mature: 17274

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPERTIPHEYLTFTLGAEEYGIDILKVQEIRGYDAVTRIANSPEFLKGVINLRGVIVP
CCCCCCCCCCCCEEEEECCHHHCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCEEE
IVDMRIRFNLGTPTYDEFTVVIIMNVLNRVIGMVVDGVSDVVALEPEQIRPAPEMGSALD
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECHHHCCCCCCCCCHHH
TRYLTGLGTVNGQMLILMDIEKLLSSSEMQLMDSAA
HHHHHCCCCCCCCEEEEEEHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MDTPERTIPHEYLTFTLGAEEYGIDILKVQEIRGYDAVTRIANSPEFLKGVINLRGVIVP
CCCCCCCCCCCCEEEEECCHHHCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHCCCEEE
IVDMRIRFNLGTPTYDEFTVVIIMNVLNRVIGMVVDGVSDVVALEPEQIRPAPEMGSALD
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECHHHCCCCCCCCCHHH
TRYLTGLGTVNGQMLILMDIEKLLSSSEMQLMDSAA
HHHHHCCCCCCCCEEEEEEHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]