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The map label for this gene is yqhT [H]

Identifier: 78222202

GI number: 78222202

Start: 1090121

End: 1091194

Strand: Direct

Name: yqhT [H]

Synonym: Gmet_0982

Alternate gene names: 78222202

Gene position: 1090121-1091194 (Clockwise)

Preceding gene: 78222201

Following gene: 78222203

Centisome position: 27.27

GC content: 60.15

Gene sequence:

>1074_bases
ATGTTACAAAACAGGATTATTAAAGCCCGAGGATGCGCGGAAAAACAGGATGTTGACGCGATTCTCTTTTTTAATCTGAG
TAACGTCCGATACCTTGCCGGTTTCACCGGGAGTGACGGTGTTTTGGTTGTCGGCCGTGATTCGTGCTGGTTTCTGACGG
ATTCCCGCTACACGACCCAGGCGGCCCGTGAGGTGACGGGGTGTTCCACGGTTGAGTACCGCGTGAAGCTCGACGGCATC
GCGGAGCTTTGTGCCAGCCAGGGATTCAGGCGGGTTGGCTTCGAGGCCGAACACACGACGGTCGCCCTCCTTACGGCCCT
CACCACAAAGGTTTCCGGCGTGGAGTTCGTTCCCCTCGGGGAGGAGCTTGCTCCACTCCGTATCGTGAAGGATGCGGAAG
AGATCGATCTGCTGGCCGAGACTGCCCGCATCGCCTCCGAAGCCCTGTTGGCGTCCCTTGACGGACTAAAGCCAGGGGTG
GTCGAGCGCGAGTATGCTCTGGATCTTGAGTTCGCCATGCGGCGGGCAGGGACCGATGACAAATCGTTCGATTTCATCGT
CGCTTCGGGCGAACGGGGTGCGCTTCCCCATGGCAGGGCCAGTACCAAGGTTATCGGGGCCGGCGAACTCGTCACCATTG
ATTTTGGCGCCATCTTTAGAGGATACCACTCCGACGAGACGGTCACCGTCTGTGTCGGCGAGCCCGATGACCGGCAGCGG
GAGATCTACGGCATTGTCAAGGAGGCCCATGATCGGGCTTTGGCTGCCGTGCGGCCGGGGGTGAGCTTCAAGGAGTTGGA
CGCCATTGCTCGCGGTTTTATCGAAGAGCGGGGATACGGGGCCTTTTTCGGCCACGGGCTTGGCCACGGGGTCGGGCTCG
ATGTTCATGAAAAGCCGGTCGTTTCCCCCCGCGGCGAAGGAGTGGCGGAAGAGGGAATGGTTTTCACCATTGAGCCGGGC
ATCTACATCCCCCAGTGGGGCGGGGTGAGGATCGAGGATGCGGTTGCGGTCACCGGCAACGGATACCGCCTCCTCACCAG
GGTGCCCAAGGAACTCATCATCTTGAATCCGTGA

Upstream 100 bases:

>100_bases
AGTCGGCCAGATCGCCGGGTTCGGTGCCGACAGTTATCTGCTCGGACTACGTGCGCTTTTTACTTATATTAAAAAAGAGA
TTGTCACCAAGGCGTGAAGC

Downstream 100 bases:

>100_bases
GCCGGGAAGATGCCCCTCTTGGTTTACGGGGTTACTTTGTAATAACCGTCTGTTTGCCATCGAGGCCGGGCGGTATCTGC
CAAAAGGAGAAAACGTATGG

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLQNRIIKARGCAEKQDVDAILFFNLSNVRYLAGFTGSDGVLVVGRDSCWFLTDSRYTTQAAREVTGCSTVEYRVKLDGI
AELCASQGFRRVGFEAEHTTVALLTALTTKVSGVEFVPLGEELAPLRIVKDAEEIDLLAETARIASEALLASLDGLKPGV
VEREYALDLEFAMRRAGTDDKSFDFIVASGERGALPHGRASTKVIGAGELVTIDFGAIFRGYHSDETVTVCVGEPDDRQR
EIYGIVKEAHDRALAAVRPGVSFKELDAIARGFIEERGYGAFFGHGLGHGVGLDVHEKPVVSPRGEGVAEEGMVFTIEPG
IYIPQWGGVRIEDAVAVTGNGYRLLTRVPKELIILNP

Sequences:

>Translated_357_residues
MLQNRIIKARGCAEKQDVDAILFFNLSNVRYLAGFTGSDGVLVVGRDSCWFLTDSRYTTQAAREVTGCSTVEYRVKLDGI
AELCASQGFRRVGFEAEHTTVALLTALTTKVSGVEFVPLGEELAPLRIVKDAEEIDLLAETARIASEALLASLDGLKPGV
VEREYALDLEFAMRRAGTDDKSFDFIVASGERGALPHGRASTKVIGAGELVTIDFGAIFRGYHSDETVTVCVGEPDDRQR
EIYGIVKEAHDRALAAVRPGVSFKELDAIARGFIEERGYGAFFGHGLGHGVGLDVHEKPVVSPRGEGVAEEGMVFTIEPG
IYIPQWGGVRIEDAVAVTGNGYRLLTRVPKELIILNP
>Mature_357_residues
MLQNRIIKARGCAEKQDVDAILFFNLSNVRYLAGFTGSDGVLVVGRDSCWFLTDSRYTTQAAREVTGCSTVEYRVKLDGI
AELCASQGFRRVGFEAEHTTVALLTALTTKVSGVEFVPLGEELAPLRIVKDAEEIDLLAETARIASEALLASLDGLKPGV
VEREYALDLEFAMRRAGTDDKSFDFIVASGERGALPHGRASTKVIGAGELVTIDFGAIFRGYHSDETVTVCVGEPDDRQR
EIYGIVKEAHDRALAAVRPGVSFKELDAIARGFIEERGYGAFFGHGLGHGVGLDVHEKPVVSPRGEGVAEEGMVFTIEPG
IYIPQWGGVRIEDAVAVTGNGYRLLTRVPKELIILNP

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=273, Percent_Identity=31.1355311355311, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI260593665, Length=295, Percent_Identity=27.7966101694915, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI149589008, Length=295, Percent_Identity=27.7966101694915, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI164420681, Length=303, Percent_Identity=27.3927392739274, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI264681563, Length=177, Percent_Identity=34.4632768361582, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788728, Length=358, Percent_Identity=36.8715083798883, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1789275, Length=278, Percent_Identity=32.0143884892086, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=26.7206477732794, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508215, Length=298, Percent_Identity=28.1879194630872, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71989583, Length=259, Percent_Identity=26.2548262548263, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17509539, Length=164, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=229, Percent_Identity=25.3275109170306, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321118, Length=281, Percent_Identity=27.0462633451957, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320922, Length=258, Percent_Identity=25.1937984496124, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357079, Length=292, Percent_Identity=29.4520547945205, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19920384, Length=288, Percent_Identity=27.0833333333333, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355531, Length=223, Percent_Identity=25.5605381165919, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38675; Mature: 38675

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNRIIKARGCAEKQDVDAILFFNLSNVRYLAGFTGSDGVLVVGRDSCWFLTDSRYTTQ
CCCCCEEECCCCCCCCCCCEEEEEEECCEEEEEEEECCCCEEEEECCCEEEEECCCHHHH
AAREVTGCSTVEYRVKLDGIAELCASQGFRRVGFEAEHTTVALLTALTTKVSGVEFVPLG
HHHHHCCCCEEEEEEEECHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECC
EELAPLRIVKDAEEIDLLAETARIASEALLASLDGLKPGVVEREYALDLEFAMRRAGTDD
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHCCCCC
KSFDFIVASGERGALPHGRASTKVIGAGELVTIDFGAIFRGYHSDETVTVCVGEPDDRQR
CCEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEHHHHHCCCCCCCEEEEEECCCCCHHH
EIYGIVKEAHDRALAAVRPGVSFKELDAIARGFIEERGYGAFFGHGLGHGVGLDVHEKPV
HHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCC
VSPRGEGVAEEGMVFTIEPGIYIPQWGGVRIEDAVAVTGNGYRLLTRVPKELIILNP
CCCCCCCCCCCCEEEEECCCEEECCCCCEEEECEEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MLQNRIIKARGCAEKQDVDAILFFNLSNVRYLAGFTGSDGVLVVGRDSCWFLTDSRYTTQ
CCCCCEEECCCCCCCCCCCEEEEEEECCEEEEEEEECCCCEEEEECCCEEEEECCCHHHH
AAREVTGCSTVEYRVKLDGIAELCASQGFRRVGFEAEHTTVALLTALTTKVSGVEFVPLG
HHHHHCCCCEEEEEEEECHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECC
EELAPLRIVKDAEEIDLLAETARIASEALLASLDGLKPGVVEREYALDLEFAMRRAGTDD
CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHCCCCC
KSFDFIVASGERGALPHGRASTKVIGAGELVTIDFGAIFRGYHSDETVTVCVGEPDDRQR
CCEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEHHHHHCCCCCCCEEEEEECCCCCHHH
EIYGIVKEAHDRALAAVRPGVSFKELDAIARGFIEERGYGAFFGHGLGHGVGLDVHEKPV
HHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCC
VSPRGEGVAEEGMVFTIEPGIYIPQWGGVRIEDAVAVTGNGYRLLTRVPKELIILNP
CCCCCCCCCCCCEEEEECCCEEECCCCCEEEECEEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]