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The map label for this gene is aroQ

Identifier: 78222201

GI number: 78222201

Start: 1089665

End: 1090117

Strand: Direct

Name: aroQ

Synonym: Gmet_0981

Alternate gene names: 78222201

Gene position: 1089665-1090117 (Clockwise)

Preceding gene: 78222200

Following gene: 78222202

Centisome position: 27.26

GC content: 57.17

Gene sequence:

>453_bases
ATGAACGTTCTTGTGGTTCACGGCCCGAACCTCAATCTCCTCGGCACCCGGGAACCGGGAATTTATGGCGTCCTTACCCT
GGACCGGATTAATGAGGAGATTTCCGCGCTGGCGGAAGAACTCGGCTGCTCGGTCTCCTTCTTCCAGTCCAACAGTGAAG
GGGCGATCATCGATGCCATACAGCAGGCCTGCGGCGCCTGTGACGGAATTCTCATCAACCCGGCAGCCTATACCCATACC
AGTGTCGCCATCCGCGACGCCCTTGCCGCCGTGGCCCTTCCAGTCGTGGAAGTTCACCTGTCCAATATCCATCGCCGTGA
GGAGTTCCGGCACCACAGTTTCATTGCCCCGGTGGCAGTCGGCCAGATCGCCGGGTTCGGTGCCGACAGTTATCTGCTCG
GACTACGTGCGCTTTTTACTTATATTAAAAAAGAGATTGTCACCAAGGCGTGA

Upstream 100 bases:

>100_bases
GGACGCTACCTGCTGCGCCGTGAAGTCTTCGGGCTGCGCGAGCGCCTTTCCTAGCATCCGCGTCCGATCCATCCCTCTTA
CCTTGTTCATGGAGGCATCG

Downstream 100 bases:

>100_bases
AGCATGTTACAAAACAGGATTATTAAAGCCCGAGGATGCGCGGAAAAACAGGATGTTGACGCGATTCTCTTTTTTAATCT
GAGTAACGTCCGATACCTTG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNVLVVHGPNLNLLGTREPGIYGVLTLDRINEEISALAEELGCSVSFFQSNSEGAIIDAIQQACGACDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRHHSFIAPVAVGQIAGFGADSYLLGLRALFTYIKKEIVTKA

Sequences:

>Translated_150_residues
MNVLVVHGPNLNLLGTREPGIYGVLTLDRINEEISALAEELGCSVSFFQSNSEGAIIDAIQQACGACDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRHHSFIAPVAVGQIAGFGADSYLLGLRALFTYIKKEIVTKA
>Mature_150_residues
MNVLVVHGPNLNLLGTREPGIYGVLTLDRINEEISALAEELGCSVSFFQSNSEGAIIDAIQQACGACDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRHHSFIAPVAVGQIAGFGADSYLLGLRALFTYIKKEIVTKA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_GEOMG (Q39X01)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383948.1
- HSSP:   Q48255
- ProteinModelPortal:   Q39X01
- SMR:   Q39X01
- STRING:   Q39X01
- GeneID:   3738085
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0981
- NMPDR:   fig|269799.3.peg.1056
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   NTHAREA
- ProtClustDB:   PRK05395
- BioCyc:   GMET269799:GMET_0981-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16068; Mature: 16068

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVVHGPNLNLLGTREPGIYGVLTLDRINEEISALAEELGCSVSFFQSNSEGAIIDAI
CCEEEEECCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
QQACGACDGILINPAAYTHTSVAIRDALAAVALPVVEVHLSNIHRREEFRHHSFIAPVAV
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GQIAGFGADSYLLGLRALFTYIKKEIVTKA
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVLVVHGPNLNLLGTREPGIYGVLTLDRINEEISALAEELGCSVSFFQSNSEGAIIDAI
CCEEEEECCCEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
QQACGACDGILINPAAYTHTSVAIRDALAAVALPVVEVHLSNIHRREEFRHHSFIAPVAV
HHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GQIAGFGADSYLLGLRALFTYIKKEIVTKA
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA