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The map label for this gene is aroB

Identifier: 78222198

GI number: 78222198

Start: 1087200

End: 1088282

Strand: Direct

Name: aroB

Synonym: Gmet_0978

Alternate gene names: 78222198

Gene position: 1087200-1088282 (Clockwise)

Preceding gene: 78222197

Following gene: 78222199

Centisome position: 27.2

GC content: 62.88

Gene sequence:

>1083_bases
GTGGAAACGCTGACGGTAGGACTTGGCGACAGAAGCTACACGATTCGGGGAGGAAGCGGAATCCTCCCGGGGATCGGTGC
GTTCTGCAGGGAGTTGGGGCTGGGGAGGATTGTCGCGGTTGTGACCAATACCACGGTGGGCCCCCTCTACTATGGCCCGG
TGGCCGACTCTCTCGCCGCGGCGGGTTTTTCGCCCCTTCGGGTGGAGCTTCCCGATGGCGAGGAGTTCAAGACCAGTGCC
ACCATGAACATCATCTACGACGCCCTCATCGACGGCGGGCTCACCCGTGATTCATTCATCGTCGCCCTCGGCGGCGGCGT
GGTTGGTGATATGGCGGGGTTTGCCGCTGCCACCTACCTGCGGGGCATCCCCTTCGTGCAGGTGCCAACCACGCTCCTTG
CCCAGGTGGACAGCAGCGTCGGCGGCAAGACCGGCATCAACCATCCCCGGGGCAAGAATCTTATCGGCGCATTCTACCAG
CCCCGTGCGGTTGTCATCGATGTGGAGACCCTCACGACGCTTCCCGAGCGGGAGTACTTGGCCGGGATGGCCGAGGTGGT
GAAGTACGGAGTCGTTCTTGATCCTCAGCTTTTCGCCGAGGTGGAGCGGAATATCACGCCGATCCTTGCCCGTGACCGTG
ACGTCCTCACCAGGATCATTATGGCCTGCTGCGCCATAAAGGCGTCGGTGGTAGAGAAGGATGAGCGGGAATCGGGGCTG
AGGGCGGTGCTTAACTACGGCCACACCCTTGGCCATGCGGTCGAAACCCTTGCGGGCTACGGAACCTTCCTCCACGGCGA
AGCGGTTGCCATCGGCATGGTGCAGGCCGCCAAGCTGGCCGAACATCGGGGTGAGGCCACTGCCGACGATACCGGCCGGC
TCCGTGCGCTTCTGGAGTCCTTGAAACTGCCGGTGGAGCTTCCAGTCTTCGCCGCAGAGGCCTATCGCGAAGTTCTCCTG
CGGGACAAGAAAGCCCGGGATACGGGACTCAGTTTCGTACTCAACAACGGGATCGGCGGCTTCTCCATCGTCAGGCTTCG
GGACCTCTCCGAGGTGATCGACGTCTGCGGGATCGGAGGGTGA

Upstream 100 bases:

>100_bases
GAACAGTTCTACGCGGATGCGGAGTTGAGGATTGACACTACCGGCAAAAGCGTGGAAGATGTGGTCGCTGAAATCACCGG
GTACTTGGAAGGAAGGTAGC

Downstream 100 bases:

>100_bases
CCATGGCACCGGAGAACGAATCATTCCGAACAGAAATCAAACGCTACGAGGATATTCTTAACGGTGATCCTGCGTCGTAC
TGCTTTGCCCCTCTGGCGGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
METLTVGLGDRSYTIRGGSGILPGIGAFCRELGLGRIVAVVTNTTVGPLYYGPVADSLAAAGFSPLRVELPDGEEFKTSA
TMNIIYDALIDGGLTRDSFIVALGGGVVGDMAGFAAATYLRGIPFVQVPTTLLAQVDSSVGGKTGINHPRGKNLIGAFYQ
PRAVVIDVETLTTLPEREYLAGMAEVVKYGVVLDPQLFAEVERNITPILARDRDVLTRIIMACCAIKASVVEKDERESGL
RAVLNYGHTLGHAVETLAGYGTFLHGEAVAIGMVQAAKLAEHRGEATADDTGRLRALLESLKLPVELPVFAAEAYREVLL
RDKKARDTGLSFVLNNGIGGFSIVRLRDLSEVIDVCGIGG

Sequences:

>Translated_360_residues
METLTVGLGDRSYTIRGGSGILPGIGAFCRELGLGRIVAVVTNTTVGPLYYGPVADSLAAAGFSPLRVELPDGEEFKTSA
TMNIIYDALIDGGLTRDSFIVALGGGVVGDMAGFAAATYLRGIPFVQVPTTLLAQVDSSVGGKTGINHPRGKNLIGAFYQ
PRAVVIDVETLTTLPEREYLAGMAEVVKYGVVLDPQLFAEVERNITPILARDRDVLTRIIMACCAIKASVVEKDERESGL
RAVLNYGHTLGHAVETLAGYGTFLHGEAVAIGMVQAAKLAEHRGEATADDTGRLRALLESLKLPVELPVFAAEAYREVLL
RDKKARDTGLSFVLNNGIGGFSIVRLRDLSEVIDVCGIGG
>Mature_360_residues
METLTVGLGDRSYTIRGGSGILPGIGAFCRELGLGRIVAVVTNTTVGPLYYGPVADSLAAAGFSPLRVELPDGEEFKTSA
TMNIIYDALIDGGLTRDSFIVALGGGVVGDMAGFAAATYLRGIPFVQVPTTLLAQVDSSVGGKTGINHPRGKNLIGAFYQ
PRAVVIDVETLTTLPEREYLAGMAEVVKYGVVLDPQLFAEVERNITPILARDRDVLTRIIMACCAIKASVVEKDERESGL
RAVLNYGHTLGHAVETLAGYGTFLHGEAVAIGMVQAAKLAEHRGEATADDTGRLRALLESLKLPVELPVFAAEAYREVLL
RDKKARDTGLSFVLNNGIGGFSIVRLRDLSEVIDVCGIGG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=340, Percent_Identity=50, Blast_Score=303, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6320332, Length=282, Percent_Identity=39.7163120567376, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_GEOMG (Q39X04)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383945.1
- ProteinModelPortal:   Q39X04
- SMR:   Q39X04
- STRING:   Q39X04
- GeneID:   3738082
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0978
- NMPDR:   fig|269799.3.peg.1053
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q39X04
- ProtClustDB:   PRK00002
- BioCyc:   GMET269799:GMET_0978-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38119; Mature: 38119

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLTVGLGDRSYTIRGGSGILPGIGAFCRELGLGRIVAVVTNTTVGPLYYGPVADSLAA
CCEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCHHHHHHH
AGFSPLRVELPDGEEFKTSATMNIIYDALIDGGLTRDSFIVALGGGVVGDMAGFAAATYL
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIPFVQVPTTLLAQVDSSVGGKTGINHPRGKNLIGAFYQPRAVVIDVETLTTLPEREYL
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHCCCCCEEEEEEHHHHCCCCHHHH
AGMAEVVKYGVVLDPQLFAEVERNITPILARDRDVLTRIIMACCAIKASVVEKDERESGL
HHHHHHHHHCCEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RAVLNYGHTLGHAVETLAGYGTFLHGEAVAIGMVQAAKLAEHRGEATADDTGRLRALLES
HHHHHHCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LKLPVELPVFAAEAYREVLLRDKKARDTGLSFVLNNGIGGFSIVRLRDLSEVIDVCGIGG
HCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
METLTVGLGDRSYTIRGGSGILPGIGAFCRELGLGRIVAVVTNTTVGPLYYGPVADSLAA
CCEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCHHHHHHH
AGFSPLRVELPDGEEFKTSATMNIIYDALIDGGLTRDSFIVALGGGVVGDMAGFAAATYL
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIPFVQVPTTLLAQVDSSVGGKTGINHPRGKNLIGAFYQPRAVVIDVETLTTLPEREYL
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHCCCCCEEEEEEHHHHCCCCHHHH
AGMAEVVKYGVVLDPQLFAEVERNITPILARDRDVLTRIIMACCAIKASVVEKDERESGL
HHHHHHHHHCCEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RAVLNYGHTLGHAVETLAGYGTFLHGEAVAIGMVQAAKLAEHRGEATADDTGRLRALLES
HHHHHHCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LKLPVELPVFAAEAYREVLLRDKKARDTGLSFVLNNGIGGFSIVRLRDLSEVIDVCGIGG
HCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA