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The map label for this gene is mreB [H]

Identifier: 78222138

GI number: 78222138

Start: 1012722

End: 1013765

Strand: Direct

Name: mreB [H]

Synonym: Gmet_0918

Alternate gene names: 78222138

Gene position: 1012722-1013765 (Clockwise)

Preceding gene: 78222135

Following gene: 78222139

Centisome position: 25.33

GC content: 62.07

Gene sequence:

>1044_bases
ATGCTTAAAATATTCGACGCCCTCTTCGGTCTTTTCTCGAACGATCTGGCAATTGACCTCGGAACAGCCAATACTCTCGT
CTACCTGAAGGGGAAGGGTATTGTGGTCCGCGAGCCGTCGGTGGTTGCCGTGCAGAAGACGAACAGCGGCCAGCAGAAGG
TGCTTGCCGTCGGCATGGAGGCCAAGAAGATGCTCGGCCGGACACCGGGAAGCATCACCGCCATCCGCCCCATGAAGGAC
GGGGTCATCGCCGACTTCGACATCACCGAGGAAATGCTCCGCTACTTCATTCACAAAGTCCACAACCGCAAGACTCTGGT
CCGGCCGCGGATCGTCATCTGCGTCCCTTCGGGGATCACCCAGGTGGAGAAGCGGGCCGTCAAGGAGTCTGCCGAGTCCG
CAGGCGCCCGGGAAGTCTACCTCATCGAGGAGCCCATGGCGGCTGCCATCGGGGCGGGGCTGCCGATCACCGAGGCCTCC
GGCAACATGATTGTCGACATCGGCGGCGGCACCACCGAGGTGGCGGTCATCTCCCTGGCAGGCATTGTCTACACGAAGAG
CGTCCGGGTGGGTGGCGACAAGATGGACGAGGCGATCGTCCAGTACATCAAGCGCAAGTACAACCTCCTCATCGGCGACC
GGACCGCTGAACTCATCAAGATCGAGATTGGCGAGGCTTACTCCATCGGGGACGTGCGTCCCATGGAGGTGAAGGGGCGC
GACCTGGTTTCCGGTATCCCGAAGACGGTGGAGATCAATTCCGACGAGATCCGCGATGCCCTCTCCGAACCGGTCAATGC
CATCGTGGATGCGGTGAAGATCTGCCTCGAACGGACCCCGCCCGAGCTTGCCGCCGATATCGTTGACAAGGGGATCGTGT
TGGCCGGCGGCGGGGCCCTGCTCCGCAACCTGGATGCGCTGCTCCGCGAGGAGACGGGACTACCGGTCGTGACCGCCGAG
GATCCCCTTTCCTGTGTTGTTCTCGGTTCCGGCAAGGTCCTCGACGAACTCAACCTCCTTCGCCGGGTTGCCGTCTCGTC
CTGA

Upstream 100 bases:

>100_bases
TCCCGGTCAAGCTTTTCCCCCTTGCATGCCCAGGGGGTTTCTGCTACGATGCAACGCTTCGAAAAAGCTCACTTTCGCGC
ACTATGAAAGGGATTAGCGC

Downstream 100 bases:

>100_bases
TTCGACCCCTGTCCGCCGTGCGGGAGAAGCGCCGCGGACAGGCCCGTTATAAGAAGCCGCATGGATGACGCGTCGCCGGG
AAGAACTGACTTCCCCGTCG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLKIFDALFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNSGQQKVLAVGMEAKKMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRTAELIKIEIGEAYSIGDVRPMEVKGR
DLVSGIPKTVEINSDEIRDALSEPVNAIVDAVKICLERTPPELAADIVDKGIVLAGGGALLRNLDALLREETGLPVVTAE
DPLSCVVLGSGKVLDELNLLRRVAVSS

Sequences:

>Translated_347_residues
MLKIFDALFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNSGQQKVLAVGMEAKKMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRTAELIKIEIGEAYSIGDVRPMEVKGR
DLVSGIPKTVEINSDEIRDALSEPVNAIVDAVKICLERTPPELAADIVDKGIVLAGGGALLRNLDALLREETGLPVVTAE
DPLSCVVLGSGKVLDELNLLRRVAVSS
>Mature_347_residues
MLKIFDALFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNSGQQKVLAVGMEAKKMLGRTPGSITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVYTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRTAELIKIEIGEAYSIGDVRPMEVKGR
DLVSGIPKTVEINSDEIRDALSEPVNAIVDAVKICLERTPPELAADIVDKGIVLAGGGALLRNLDALLREETGLPVVTAE
DPLSCVVLGSGKVLDELNLLRRVAVSS

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=341, Percent_Identity=63.049853372434, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37126; Mature: 37126

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFDALFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNSGQQKVLAVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCEEEEECHH
AKKMLGRTPGSITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVYTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRTAELIKIEIGEAYSIGDVRPMEVKGR
HHHEEEEEECCCCHHHHHHHHHHHHHHCEEEECCCEEEEEEEECCEEECCCCCEEEECCC
DLVSGIPKTVEINSDEIRDALSEPVNAIVDAVKICLERTPPELAADIVDKGIVLAGGGAL
HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCHHH
LRNLDALLREETGLPVVTAEDPLSCVVLGSGKVLDELNLLRRVAVSS
HHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKIFDALFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNSGQQKVLAVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCEEEEECHH
AKKMLGRTPGSITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVYTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRTAELIKIEIGEAYSIGDVRPMEVKGR
HHHEEEEEECCCCHHHHHHHHHHHHHHCEEEECCCEEEEEEEECCEEECCCCCEEEECCC
DLVSGIPKTVEINSDEIRDALSEPVNAIVDAVKICLERTPPELAADIVDKGIVLAGGGAL
HHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCHHH
LRNLDALLREETGLPVVTAEDPLSCVVLGSGKVLDELNLLRRVAVSS
HHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]