Click here to switch to the map view.

The map label for this gene is wrbA

Identifier: 78221991

GI number: 78221991

Start: 848051

End: 848662

Strand: Reverse

Name: wrbA

Synonym: Gmet_0771

Alternate gene names: 78221991

Gene position: 848662-848051 (Counterclockwise)

Preceding gene: 78221992

Following gene: 78221990

Centisome position: 21.23

GC content: 65.69

Gene sequence:

>612_bases
ATGAAGGTACTCATTCCGTTCTATTCCATGTACGGCCACATTTACCGGATGGCCGAGGCCGTGGCCGAAGGGGTCCGGGA
GGTCTCGGGCGCCGAGGCGGTGCTCCGCCGTGTCCCGGAAACCCTGCCAACCGACGTATTGCAGAAAATGGGGGCCGTCG
AGCCCCAGAAGGCCTTTGCCCACATCCCCGTCTGCACCGTGGACGAGTTGGCCGCCGCCGACGCCATCATCTTCGGCACC
CCGACCCGCTTCGGCAACATGTGCGGCCAGATGCGCCAGTTCCTGGACGCCACCGGCGGCCTCTGGGTGAAGGGAGGCCT
CGTGGGGAAGGCGGGAGGGGTCTTCACCAGCTCCGCCACCCAGCACGGCGGCCAGGAGTCCACCATCCTCACCTTCCACA
CCTTCCTCCTCCACCAGGGGATGGTGCTCGTGGGGCTCCCCTACGCCTTTGCCGGCCAGATGCGGATCGACGAGATCACC
GGTGGTTCCCCCTACGGCGCCTCCACCATTGCCGGAGGCCAGGGAGAGCGTCTCCCCAGCGAGAACGAACTGGCCGGCGC
CCGCTACCAAGGGAAGTACATTGCGGAAATCGCGGCGAAGCTAAAAGGATAA

Upstream 100 bases:

>100_bases
GCCACTGACCCTCCCCGCCGACCTCCCTTCCGTTGCATCAGCCCCGTAATGCGGTACCCTTGATGATGCCGAACATACTT
GCATCAAGGAGGACTCACCC

Downstream 100 bases:

>100_bases
ACCCCTCACCCGGCCTACGGCCACCCTCTCCCCGAGGGAGGGGTTTGGTGTCTCCCCTCGCCCTCGGTGAGAGGGGCTGG
GGGCGAGGGGCAACAGGGAG

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFAHIPVCTVDELAAADAIIFGT
PTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSATQHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEIT
GGSPYGASTIAGGQGERLPSENELAGARYQGKYIAEIAAKLKG

Sequences:

>Translated_203_residues
MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFAHIPVCTVDELAAADAIIFGT
PTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSATQHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEIT
GGSPYGASTIAGGQGERLPSENELAGARYQGKYIAEIAAKLKG
>Mature_203_residues
MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFAHIPVCTVDELAAADAIIFGT
PTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSATQHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEIT
GGSPYGASTIAGGQGERLPSENELAGARYQGKYIAEIAAKLKG

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=202, Percent_Identity=56.9306930693069, Blast_Score=215, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6319849, Length=203, Percent_Identity=48.7684729064039, Blast_Score=169, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320235, Length=202, Percent_Identity=43.5643564356436, Blast_Score=148, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319526, Length=200, Percent_Identity=33.5, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_GEOMG (Q39XL1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383738.1
- ProteinModelPortal:   Q39XL1
- STRING:   Q39XL1
- GeneID:   3739334
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0771
- NMPDR:   fig|269799.3.peg.798
- eggNOG:   COG0655
- HOGENOM:   HBG686708
- OMA:   TITSFHT
- PhylomeDB:   Q39XL1
- ProtClustDB:   PRK03767
- BioCyc:   GMET269799:GMET_0771-MONOMER
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 21538; Mature: 21538

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHH
HIPVCTVDELAAADAIIFGTPTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSAT
CCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCEECCHH
QHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEITGGSPYGASTIAGGQGERLPS
HCCCCCCHHHHHHHHHHHCCHHEEECCHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCC
ENELAGARYQGKYIAEIAAKLKG
CCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHH
HIPVCTVDELAAADAIIFGTPTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSAT
CCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCEECCHH
QHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEITGGSPYGASTIAGGQGERLPS
HCCCCCCHHHHHHHHHHHCCHHEEECCHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCC
ENELAGARYQGKYIAEIAAKLKG
CCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA