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The map label for this gene is yciA [C]

Identifier: 78221989

GI number: 78221989

Start: 845100

End: 845543

Strand: Reverse

Name: yciA [C]

Synonym: Gmet_0769

Alternate gene names: 78221989

Gene position: 845543-845100 (Counterclockwise)

Preceding gene: 78221990

Following gene: 78221988

Centisome position: 21.15

GC content: 68.02

Gene sequence:

>444_bases
ATGAACCGCGACTGGACCCTCATCGAGACCCTCCTCCCCCAGGACACCAATTCTGCGGGAAACATCTTCGGCGGGGTGCT
CATGAGCCTCATGGACAAGGCGGCGGCCATCACCGCCTGGCGCTACGCCCGGTGCGACATGGTCACCGCCGGGGCCGAGG
AGATCGCCTTCATCCGGCCGGTGCATGTGGGGGAGGTGGTCAAGGTGGAGGCCCGGGTGGTCTGTACCGGCCGAACGTCC
ATCGACATGGCGGTAATGGTTGAGGCGGAGGATGTCTTCACGGGGCAGAGTTACGAGGCGGCCCGGGGATACTTCACCAT
GGTGGCCCTGGACAAGGGAGGGAAGCCGACGGAGGTCCCGCCGTGGGAACCCCGCACCGAGGAGGAGCGGCGCCGCTGCG
AAGCGTCCGGGGAGCGCCGGGCCAGGCGCCGGGAGAGGAAGTGA

Upstream 100 bases:

>100_bases
TCCTGGTTCGGGAGGGGATCGACTCCATCTCGTTAAATCCGGACTCGATCCTGAAGATCACCTTGCGGGTGCTGGAGATG
GAAAAGGAGATAGAGAAACC

Downstream 100 bases:

>100_bases
CCAACGCGGCAATTATCGCAGCCCAAGAGGGCTTCTCCGGAGGCCCTCTTGCTTTTATGGGACAAACACCGATTAATCCC
TTCCTGATTAACCTACGAAA

Product: thioesterase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNRDWTLIETLLPQDTNSAGNIFGGVLMSLMDKAAAITAWRYARCDMVTAGAEEIAFIRPVHVGEVVKVEARVVCTGRTS
IDMAVMVEAEDVFTGQSYEAARGYFTMVALDKGGKPTEVPPWEPRTEEERRRCEASGERRARRRERK

Sequences:

>Translated_147_residues
MNRDWTLIETLLPQDTNSAGNIFGGVLMSLMDKAAAITAWRYARCDMVTAGAEEIAFIRPVHVGEVVKVEARVVCTGRTS
IDMAVMVEAEDVFTGQSYEAARGYFTMVALDKGGKPTEVPPWEPRTEEERRRCEASGERRARRRERK
>Mature_147_residues
MNRDWTLIETLLPQDTNSAGNIFGGVLMSLMDKAAAITAWRYARCDMVTAGAEEIAFIRPVHVGEVVKVEARVVCTGRTS
IDMAVMVEAEDVFTGQSYEAARGYFTMVALDKGGKPTEVPPWEPRTEEERRRCEASGERRARRRERK

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=131, Percent_Identity=35.1145038167939, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI32528286, Length=131, Percent_Identity=35.1145038167939, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI75709208, Length=144, Percent_Identity=32.6388888888889, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI32528282, Length=131, Percent_Identity=35.1145038167939, Blast_Score=86, Evalue=9e-18,
Organism=Homo sapiens, GI22165400, Length=135, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI22165355, Length=135, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787506, Length=120, Percent_Identity=42.5, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 16498; Mature: 16498

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDWTLIETLLPQDTNSAGNIFGGVLMSLMDKAAAITAWRYARCDMVTAGAEEIAFIRP
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHEEEECC
VHVGEVVKVEARVVCTGRTSIDMAVMVEAEDVFTGQSYEAARGYFTMVALDKGGKPTEVP
CCCCCEEEEEEEEEEECCCCEEEEEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
PWEPRTEEERRRCEASGERRARRRERK
CCCCCCHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MNRDWTLIETLLPQDTNSAGNIFGGVLMSLMDKAAAITAWRYARCDMVTAGAEEIAFIRP
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHEEEECC
VHVGEVVKVEARVVCTGRTSIDMAVMVEAEDVFTGQSYEAARGYFTMVALDKGGKPTEVP
CCCCCEEEEEEEEEEECCCCEEEEEEEEHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
PWEPRTEEERRRCEASGERRARRRERK
CCCCCCHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]