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The map label for this gene is qseB [H]

Identifier: 78221908

GI number: 78221908

Start: 756057

End: 756719

Strand: Reverse

Name: qseB [H]

Synonym: Gmet_0688

Alternate gene names: 78221908

Gene position: 756719-756057 (Counterclockwise)

Preceding gene: 78221909

Following gene: 78221907

Centisome position: 18.93

GC content: 61.69

Gene sequence:

>663_bases
ATGCGAATTTTGTTGGTTGAAGATGACCGGATGATTGGCGAGGCGGTGGAACAAGCGTTGAAGGATGCCGCCTATGCCGT
GGACTGGGTCCGTGACGGCATCAGCGCCTCCGACGCCGTTGAAACCGGCGAATATCAACTGGTGATCCTCGATCTGGGGC
TCCCCGGACGGGACGGTCTGGGGGTGCTGGAACGGATGCGCGGCGACGGGAACAACGCCGCCGTTCTCATCGTCACTGCC
CGCGATGCCCTCGATGACCGGATTCGTGGCCTCGATCTGGGTGCGGACGACTATCTGGTCAAGCCGTTCGCGGTAGGCGA
ACTGCTGGCCAGGATCCGGGCCGTAAGCCGCCGCCAGACGGGGAGCGCTGCCCCACTTCTTACGAACGGGGTCGTTACCC
TTGACCCGGTTAGCAAGGAAGCCGTCTGCGGCGAACGGCGCTGCCGCCTCACCGCCCGTGAGTTCTCGCTACTGCAGGCT
CTGCTCGTGCGCCCCGGCGCAATCCTTTCCCGTGATGAGCTGGAAACCCGCATCTATGGCTGGAATGAGGAAGTGGAGAG
CAATGCCGTCGAATTCCTGATCCATTCGGTACGCAAGAAACTGGGGAGCGAGTCAATCAGAAATGTTCGGGGGATGGGAT
GGATGGTGGATCGCAACCAGTGA

Upstream 100 bases:

>100_bases
GGTATATCCGACAACATTGGCGCTGACCGAGCTTGCGTAACGGATGCCAAAGCCGGTTGATGATTCTGTTTGCCCGGCAA
GCGTTCCGCACGGAGAGATA

Downstream 100 bases:

>100_bases
ACGGCTCCCTGCGACGCCGGCTTTCGCTCTGGATTGCCGGGGTGACCATTGCAAGCGGCCTGGCGGCAGGGTTCTGTTCA
TACCTCATGGCGTTTCGGGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRILLVEDDRMIGEAVEQALKDAAYAVDWVRDGISASDAVETGEYQLVILDLGLPGRDGLGVLERMRGDGNNAAVLIVTA
RDALDDRIRGLDLGADDYLVKPFAVGELLARIRAVSRRQTGSAAPLLTNGVVTLDPVSKEAVCGERRCRLTAREFSLLQA
LLVRPGAILSRDELETRIYGWNEEVESNAVEFLIHSVRKKLGSESIRNVRGMGWMVDRNQ

Sequences:

>Translated_220_residues
MRILLVEDDRMIGEAVEQALKDAAYAVDWVRDGISASDAVETGEYQLVILDLGLPGRDGLGVLERMRGDGNNAAVLIVTA
RDALDDRIRGLDLGADDYLVKPFAVGELLARIRAVSRRQTGSAAPLLTNGVVTLDPVSKEAVCGERRCRLTAREFSLLQA
LLVRPGAILSRDELETRIYGWNEEVESNAVEFLIHSVRKKLGSESIRNVRGMGWMVDRNQ
>Mature_220_residues
MRILLVEDDRMIGEAVEQALKDAAYAVDWVRDGISASDAVETGEYQLVILDLGLPGRDGLGVLERMRGDGNNAAVLIVTA
RDALDDRIRGLDLGADDYLVKPFAVGELLARIRAVSRRQTGSAAPLLTNGVVTLDPVSKEAVCGERRCRLTAREFSLLQA
LLVRPGAILSRDELETRIYGWNEEVESNAVEFLIHSVRKKLGSESIRNVRGMGWMVDRNQ

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=46.2962962962963, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=43.6363636363636, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=39.4495412844037, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.375, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=31.6742081447964, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=31.858407079646, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786911, Length=210, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=30.1369863013699, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=29.3859649122807, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=27.5555555555556, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=31.3559322033898, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24216; Mature: 24216

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDRMIGEAVEQALKDAAYAVDWVRDGISASDAVETGEYQLVILDLGLPGRDGL
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCH
GVLERMRGDGNNAAVLIVTARDALDDRIRGLDLGADDYLVKPFAVGELLARIRAVSRRQT
HHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GSAAPLLTNGVVTLDPVSKEAVCGERRCRLTAREFSLLQALLVRPGAILSRDELETRIYG
CCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEC
WNEEVESNAVEFLIHSVRKKLGSESIRNVRGMGWMVDRNQ
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MRILLVEDDRMIGEAVEQALKDAAYAVDWVRDGISASDAVETGEYQLVILDLGLPGRDGL
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCH
GVLERMRGDGNNAAVLIVTARDALDDRIRGLDLGADDYLVKPFAVGELLARIRAVSRRQT
HHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
GSAAPLLTNGVVTLDPVSKEAVCGERRCRLTAREFSLLQALLVRPGAILSRDELETRIYG
CCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEC
WNEEVESNAVEFLIHSVRKKLGSESIRNVRGMGWMVDRNQ
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]