Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 78221907

GI number: 78221907

Start: 754741

End: 756081

Strand: Reverse

Name: qseC [H]

Synonym: Gmet_0687

Alternate gene names: 78221907

Gene position: 756081-754741 (Counterclockwise)

Preceding gene: 78221908

Following gene: 78221900

Centisome position: 18.91

GC content: 61.45

Gene sequence:

>1341_bases
ATGGATGGTGGATCGCAACCAGTGAACGGCTCCCTGCGACGCCGGCTTTCGCTCTGGATTGCCGGGGTGACCATTGCAAG
CGGCCTGGCGGCAGGGTTCTGTTCATACCTCATGGCGTTTCGGGAGGCCCAGGAACTCCAGGATGACCAGCTCCGCCAGA
TGGCTCTGCTGCTGGGGCGTCACGCGCAAACGTCGGATGCGTGGATGAGCCCCATGGGAAGTATCGACCACAACGATCCC
GACGCCAGAATCGTTGTCTCTCCCCTGGGGAACGTTCCCCGCCCCCCGAAGCTGCCCCCTCTTCCCACCACATTGCCCGA
AGGATTCCAAACCCTGGACAACCACGGAACCGCCTGGCGCCTCTTCGTCTTCACCCTTCCGTCCGGCATGCGGCTTGCGA
CGGGACAGATGACGGCGGTGCGCAATGAGATAGCTCGGGACAGTGCCCTTTTCACCCTGATCCCGATACTGCTGCTGGTG
CCGACGCTGTCTTTTCTGGCAGCCTGGGTCATCCGGCACACCCTGATGCCAGTCACGCATCTTTCCCATCAACTGGACCG
GCGGGATGACACCAACCTGGCGGCGGTCTCGGTGGTCGGCGTACCGTCGGAGATACGCCCCTTTGTTATCGCCATCAACG
GCCTGATGCAACGCCTCGCTACAGCCATCGAGCAGCAGCGCCGTTTCATCGCCGACGCAGCCCATGAGCTGCGCTCCCCC
CTCACGGCCCTCACCGTTCAGGCGGAAAACCTGGAACACGGCATTTCATCTCCAGAGGGAAAACTGCGGGTTATGCAACT
CAAGGCAGGACTGGAGCGGGCCGGGAAATTGCTGGAACAGCTTTTGAGCCTGGCGCGGCACCAATCCTGCGCAGCGCCCC
CGGTTGAAGTGCTCTTCAGTCATCTGGTCAGGCAGGTTATCGAGGATTACATGCCGTTCGCCGCCGGCAAACGGATTGAT
TTCGGCTGTGAGCGGTTCGAGGAGGTTACCCTGATCGCCCCTTCGGAAGACTTGCTGGTGCTGGCGCGTAACGCCGTTGA
CAATGCGCTGCGCTATACGCCGCCGGGCGGGACGGTTGATGTCAGTCTGTACCGCGACAAGGAAGATGTGGTTTTCCAGG
TGGATGATACCGGGCCGGGGATTCCCGAAGGTGAAGAGGAGCGGATGTTTGAACCGTTCTATCGGGTAACGGGAAACAAT
GAAACCGGCAGCGGTCTCGGACTGGCAATCATACGCAGCATTGCGGACCGGCTTGGAGGCACCGTGACGCTTTGCAACAG
GGAAGGCGGGACAGGTGCGCGCTTCCGCTACCGACAACCGCTACCCGCAAGCAACCGGTGA

Upstream 100 bases:

>100_bases
GCTGGAATGAGGAAGTGGAGAGCAATGCCGTCGAATTCCTGATCCATTCGGTACGCAAGAAACTGGGGAGCGAGTCAATC
AGAAATGTTCGGGGGATGGG

Downstream 100 bases:

>100_bases
CAACATCATCGACACATCAGAACTCACGCCTCGGGAAACTCGTCCAACCCAATGAGAGTCTCCCGCAATTCGTACCGCGC
AACGGCGAAGAGCTTCTCCA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDGGSQPVNGSLRRRLSLWIAGVTIASGLAAGFCSYLMAFREAQELQDDQLRQMALLLGRHAQTSDAWMSPMGSIDHNDP
DARIVVSPLGNVPRPPKLPPLPTTLPEGFQTLDNHGTAWRLFVFTLPSGMRLATGQMTAVRNEIARDSALFTLIPILLLV
PTLSFLAAWVIRHTLMPVTHLSHQLDRRDDTNLAAVSVVGVPSEIRPFVIAINGLMQRLATAIEQQRRFIADAAHELRSP
LTALTVQAENLEHGISSPEGKLRVMQLKAGLERAGKLLEQLLSLARHQSCAAPPVEVLFSHLVRQVIEDYMPFAAGKRID
FGCERFEEVTLIAPSEDLLVLARNAVDNALRYTPPGGTVDVSLYRDKEDVVFQVDDTGPGIPEGEEERMFEPFYRVTGNN
ETGSGLGLAIIRSIADRLGGTVTLCNREGGTGARFRYRQPLPASNR

Sequences:

>Translated_446_residues
MDGGSQPVNGSLRRRLSLWIAGVTIASGLAAGFCSYLMAFREAQELQDDQLRQMALLLGRHAQTSDAWMSPMGSIDHNDP
DARIVVSPLGNVPRPPKLPPLPTTLPEGFQTLDNHGTAWRLFVFTLPSGMRLATGQMTAVRNEIARDSALFTLIPILLLV
PTLSFLAAWVIRHTLMPVTHLSHQLDRRDDTNLAAVSVVGVPSEIRPFVIAINGLMQRLATAIEQQRRFIADAAHELRSP
LTALTVQAENLEHGISSPEGKLRVMQLKAGLERAGKLLEQLLSLARHQSCAAPPVEVLFSHLVRQVIEDYMPFAAGKRID
FGCERFEEVTLIAPSEDLLVLARNAVDNALRYTPPGGTVDVSLYRDKEDVVFQVDDTGPGIPEGEEERMFEPFYRVTGNN
ETGSGLGLAIIRSIADRLGGTVTLCNREGGTGARFRYRQPLPASNR
>Mature_446_residues
MDGGSQPVNGSLRRRLSLWIAGVTIASGLAAGFCSYLMAFREAQELQDDQLRQMALLLGRHAQTSDAWMSPMGSIDHNDP
DARIVVSPLGNVPRPPKLPPLPTTLPEGFQTLDNHGTAWRLFVFTLPSGMRLATGQMTAVRNEIARDSALFTLIPILLLV
PTLSFLAAWVIRHTLMPVTHLSHQLDRRDDTNLAAVSVVGVPSEIRPFVIAINGLMQRLATAIEQQRRFIADAAHELRSP
LTALTVQAENLEHGISSPEGKLRVMQLKAGLERAGKLLEQLLSLARHQSCAAPPVEVLFSHLVRQVIEDYMPFAAGKRID
FGCERFEEVTLIAPSEDLLVLARNAVDNALRYTPPGGTVDVSLYRDKEDVVFQVDDTGPGIPEGEEERMFEPFYRVTGNN
ETGSGLGLAIIRSIADRLGGTVTLCNREGGTGARFRYRQPLPASNR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=453, Percent_Identity=32.0088300220751, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=28.7625418060201, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788279, Length=323, Percent_Identity=25.3869969040248, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=260, Percent_Identity=31.1538461538462, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=34.7107438016529, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=33.0508474576271, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=309, Percent_Identity=27.1844660194175, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=28.4403669724771, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=27.8985507246377, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=30.9236947791165, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=28.8888888888889, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=28.3842794759825, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=251, Percent_Identity=27.8884462151394, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787374, Length=363, Percent_Identity=22.3140495867769, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=97, Percent_Identity=37.1134020618557, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=25.78125, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=26.0683760683761, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=24.0909090909091, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48918; Mature: 48918

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGGSQPVNGSLRRRLSLWIAGVTIASGLAAGFCSYLMAFREAQELQDDQLRQMALLLGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HAQTSDAWMSPMGSIDHNDPDARIVVSPLGNVPRPPKLPPLPTTLPEGFQTLDNHGTAWR
CCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
LFVFTLPSGMRLATGQMTAVRNEIARDSALFTLIPILLLVPTLSFLAAWVIRHTLMPVTH
EEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHQLDRRDDTNLAAVSVVGVPSEIRPFVIAINGLMQRLATAIEQQRRFIADAAHELRSP
HHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTALTVQAENLEHGISSPEGKLRVMQLKAGLERAGKLLEQLLSLARHQSCAAPPVEVLFS
HHHEEEEHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HLVRQVIEDYMPFAAGKRIDFGCERFEEVTLIAPSEDLLVLARNAVDNALRYTPPGGTVD
HHHHHHHHHHCCHHCCCCCCCCHHHHCCEEEECCCCCCEEEEHHHHHCCCEECCCCCEEE
VSLYRDKEDVVFQVDDTGPGIPEGEEERMFEPFYRVTGNNETGSGLGLAIIRSIADRLGG
EEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
TVTLCNREGGTGARFRYRQPLPASNR
EEEEEECCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MDGGSQPVNGSLRRRLSLWIAGVTIASGLAAGFCSYLMAFREAQELQDDQLRQMALLLGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HAQTSDAWMSPMGSIDHNDPDARIVVSPLGNVPRPPKLPPLPTTLPEGFQTLDNHGTAWR
CCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
LFVFTLPSGMRLATGQMTAVRNEIARDSALFTLIPILLLVPTLSFLAAWVIRHTLMPVTH
EEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHQLDRRDDTNLAAVSVVGVPSEIRPFVIAINGLMQRLATAIEQQRRFIADAAHELRSP
HHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LTALTVQAENLEHGISSPEGKLRVMQLKAGLERAGKLLEQLLSLARHQSCAAPPVEVLFS
HHHEEEEHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HLVRQVIEDYMPFAAGKRIDFGCERFEEVTLIAPSEDLLVLARNAVDNALRYTPPGGTVD
HHHHHHHHHHCCHHCCCCCCCCHHHHCCEEEECCCCCCEEEEHHHHHCCCEECCCCCEEE
VSLYRDKEDVVFQVDDTGPGIPEGEEERMFEPFYRVTGNNETGSGLGLAIIRSIADRLGG
EEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
TVTLCNREGGTGARFRYRQPLPASNR
EEEEEECCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]