Click here to switch to the map view.

The map label for this gene is trxB/A [H]

Identifier: 78221738

GI number: 78221738

Start: 556176

End: 556553

Strand: Reverse

Name: trxB/A [H]

Synonym: Gmet_0517

Alternate gene names: 78221738

Gene position: 556553-556176 (Counterclockwise)

Preceding gene: 78221739

Following gene: 78221737

Centisome position: 13.92

GC content: 55.03

Gene sequence:

>378_bases
ATGCGTTTTCTCACTCTCCTTTTCCTGCTCCTCACTGCAACTGTTGCGCGGGCGGAGCTTCCTTCGGCCACCGATGACGC
TATCAACAAAGCCCTTGCCTCGGGCAAGCCAGCGGTCATCGACCTGGGGGCCAGATACTGCATACCCTGCAAGAAAATGG
CTCCGATCCTCGAATCTCTAGCGACAGAATATAGGGGAAAAGCAACTGTTCTATTCATCGACGTCAATGAAAACCAAGCC
GCGCCGAAGCGGTTCCGGGTGCAGATGATCCCGACCCAGATATTTTTCGACGCCCGTGGGAAGGAAGTGAAGCGGCACAT
GGGCTTCATGGACAAGGCTGATATCGTCAAGGAACTGAATGCCCTGGGCGTGCGATGA

Upstream 100 bases:

>100_bases
TGAAGTACGGGGTGATGCGCACTCCCGCGCTGGTGGTCGACGGGGTAGTCAAATTCTCCGGCAAAGTGGCCTCGCCGGAC
GAGATCAGGGGGATGCTGTG

Downstream 100 bases:

>100_bases
GCCTCCTCGACAATATCGAGCAGATTGTCGCGACGCAGCCGCTTCTGGCCTTCGGCGCGGTCTTTATGGGAGGAGTCCTC
TCGTCTGCCTCCCCCTGCGT

Product: thioredoxin-related protein

Products: NA

Alternate protein names: Thioredoxin reductase; TRXR; Thioredoxin [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MRFLTLLFLLLTATVARAELPSATDDAINKALASGKPAVIDLGARYCIPCKKMAPILESLATEYRGKATVLFIDVNENQA
APKRFRVQMIPTQIFFDARGKEVKRHMGFMDKADIVKELNALGVR

Sequences:

>Translated_125_residues
MRFLTLLFLLLTATVARAELPSATDDAINKALASGKPAVIDLGARYCIPCKKMAPILESLATEYRGKATVLFIDVNENQA
APKRFRVQMIPTQIFFDARGKEVKRHMGFMDKADIVKELNALGVR
>Mature_125_residues
MRFLTLLFLLLTATVARAELPSATDDAINKALASGKPAVIDLGARYCIPCKKMAPILESLATEYRGKATVLFIDVNENQA
APKRFRVQMIPTQIFFDARGKEVKRHMGFMDKADIVKELNALGVR

Specific function: Participates In Various Redox Reactions Through The Reversible Oxidation Of Its Active Center Dithiol To A Disulfide And Catalyzes Dithiol-Disulfide Exchange Reactions. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=99, Percent_Identity=31.3131313131313, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF00085 Thioredoxin [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 13868; Mature: 13868

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLTLLFLLLTATVARAELPSATDDAINKALASGKPAVIDLGARYCIPCKKMAPILESL
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
ATEYRGKATVLFIDVNENQAAPKRFRVQMIPTQIFFDARGKEVKRHMGFMDKADIVKELN
HHHHCCCEEEEEEECCCCCCCCHHEEEEECCHHEEECCCCHHHHHHCCCCCHHHHHHHHH
ALGVR
HHCCC
>Mature Secondary Structure
MRFLTLLFLLLTATVARAELPSATDDAINKALASGKPAVIDLGARYCIPCKKMAPILESL
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
ATEYRGKATVLFIDVNENQAAPKRFRVQMIPTQIFFDARGKEVKRHMGFMDKADIVKELN
HHHHCCCEEEEEEECCCCCCCCHHEEEEECCHHEEECCCCHHHHHHCCCCCHHHHHHHHH
ALGVR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969512; 7476189; 11234002 [H]