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The map label for this gene is sirB [H]

Identifier: 78221697

GI number: 78221697

Start: 522445

End: 522867

Strand: Direct

Name: sirB [H]

Synonym: Gmet_0476

Alternate gene names: 78221697

Gene position: 522445-522867 (Clockwise)

Preceding gene: 78221696

Following gene: 78221698

Centisome position: 13.07

GC content: 62.41

Gene sequence:

>423_bases
GTGTCCTCTGTGATCTCTGTGGCAAAGAATGGAGTGCTCATGAAAACCGCAATTTTACTGATGGCCCACGGGAGCCGCAT
TGCCGAGGCTAACAACGCCGTGCGGGAGATCGCCGCCATGGTAAAGGAAATGACCGGCTACGACATCGTTGAGGTGTCGT
TCCGGGAACAGCACCTTCCCAACATCCAGGAGGGGATCGACGCTTGCGTGGCGAAAGGGGCGAGGCGGGTGCTGCTGATG
CCCTACTTCCTCTTCGTGGGGGCCCACGTCCAGGAGGACCTTCCCGAGGAGATGGCCCAGGCCCGGGAGCGCTACCCCAA
AGTCGAATTCGCCATGGGGCCGCACCTTGGTGTTCACCGCAAGCTGGCCGAGGTGGAAGTGGAGCGGATCGCCGAGGCCC
TCACCGCCACGGGGTGGCACTGA

Upstream 100 bases:

>100_bases
GAAATACTGCAAAAACATTAGCCACAGAGGACACAGAGCGCACAGAGAATGGCTTTTGGCCCATGAGTCTTGGAAAACGG
AGTTTGTTTCCTTTTTCTCT

Downstream 100 bases:

>100_bases
TGTCGGTCCACCTCGCCCCCGAGGAGATCGAGGCCGAATCGTTCCGCCTCATCGATGAAGAAGTGGGAACCCATCACTGG
GGGCCTGCCGAGTGGCCGGT

Product: cobalamin (vitamin B12) biosynthesis CbiX protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSSVISVAKNGVLMKTAILLMAHGSRIAEANNAVREIAAMVKEMTGYDIVEVSFREQHLPNIQEGIDACVAKGARRVLLM
PYFLFVGAHVQEDLPEEMAQARERYPKVEFAMGPHLGVHRKLAEVEVERIAEALTATGWH

Sequences:

>Translated_140_residues
MSSVISVAKNGVLMKTAILLMAHGSRIAEANNAVREIAAMVKEMTGYDIVEVSFREQHLPNIQEGIDACVAKGARRVLLM
PYFLFVGAHVQEDLPEEMAQARERYPKVEFAMGPHLGVHRKLAEVEVERIAEALTATGWH
>Mature_139_residues
SSVISVAKNGVLMKTAILLMAHGSRIAEANNAVREIAAMVKEMTGYDIVEVSFREQHLPNIQEGIDACVAKGARRVLLMP
YFLFVGAHVQEDLPEEMAQARERYPKVEFAMGPHLGVHRKLAEVEVERIAEALTATGWH

Specific function: Chelates iron to the siroheme precursor [H]

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. SirB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002762 [H]

Pfam domain/function: PF01903 CbiX [H]

EC number: =4.99.1.4 [H]

Molecular weight: Translated: 15510; Mature: 15379

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVISVAKNGVLMKTAILLMAHGSRIAEANNAVREIAAMVKEMTGYDIVEVSFREQHLP
CCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCC
NIQEGIDACVAKGARRVLLMPYFLFVGAHVQEDLPEEMAQARERYPKVEFAMGPHLGVHR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHH
KLAEVEVERIAEALTATGWH
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSVISVAKNGVLMKTAILLMAHGSRIAEANNAVREIAAMVKEMTGYDIVEVSFREQHLP
CHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHCCC
NIQEGIDACVAKGARRVLLMPYFLFVGAHVQEDLPEEMAQARERYPKVEFAMGPHLGVHR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHH
KLAEVEVERIAEALTATGWH
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA