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The map label for this gene is 78221676

Identifier: 78221676

GI number: 78221676

Start: 502453

End: 503313

Strand: Reverse

Name: 78221676

Synonym: Gmet_0455

Alternate gene names: NA

Gene position: 503313-502453 (Counterclockwise)

Preceding gene: 78221677

Following gene: 78221675

Centisome position: 12.59

GC content: 57.84

Gene sequence:

>861_bases
ATGAGCAGCCCCCTTTTCGTAGCAGAGGTATCCAGCAATCACCACCGCGACCTGGAGCGCTGCTTTCGCTTCATCGACAC
CGCAGCGGCCGTAGGCTGTGGAGCGGTAAAGTTCCAGCTTTTCCGAGTCGAGGAACTCTTCGCGCCGGAAGTTCTCGCCA
AGAGCCCCGTGCTCAGGGCACGGAAAGCATGGGAACTCCCCGTTGAATTTCTCTCTCCCCTCGCCGAGAGGTGCCGAAAG
CAGGGGATTCAGTTTTCGTGCACCCCCTTTTACCTCCAGGCGGTAGAAGAGCTCTTGCCGTATGTGGATTTTTATAAAAT
CGCATCATATGAGCTTCTCTGGAATGACCTGTTACGGGCATGTGCCGCGACCGGAAAACCCGTGATCCTTTCAACAGGGA
TGGCCACACTGGACGAGATTGGCGGTGCGGTGGAAATGCTGCGCACAGCGGGGTGCAGGGATCTTACCCTGCTCCACTGT
GTTTCCGGGTATCCTGCCCCCCCAGAAGAGTGCAACCTCGCAGCCATTGAAACCATTCGCTCACGCTTCGGTTGCCCGGT
AGGCTGGTCCGACCATAGCGTCTCCCCTGCAGTAATCCAGCGGGCAGTGCATCAGTGGGAAGCCAGTGCAGTGGAGTTCC
ATCTCGACCTGGAAGGTGAGGGAGAAGAGTTCGCGACCGGCCATTGCTGGCTCCCTGACGGAATCAAAGCCGTCATTGCG
GATGTGAGCACTGCTCTGTCTGCAGACGGCACAGGAGAAAAGGTGCCCACCCCCGTTGAGTTCCCTGACCGCGAATGGCG
TGCCGACCCTTCCGACGGCTTGAGACCTTTTCTGCATGTAAGGAACGAATGGAATGGCTAA

Upstream 100 bases:

>100_bases
CCTTTTCTTCTCGCCCGACTGAAGAGTGTAGATAAGGAGCGGGTATAGTGATATTTCAAAAGGCTCTTGAACCAATTACA
GGCCGACTTCAGGAGAACAC

Downstream 100 bases:

>100_bases
AAAGAAAATTGTAGCTGTCATTCAAGCCCGCATGGGTTCTTCGCGCCTGCCGGGAAAGGTGCTCATGACAGTGGCGGGCA
AACCGCTGCTTGAGCATATT

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSSPLFVAEVSSNHHRDLERCFRFIDTAAAVGCGAVKFQLFRVEELFAPEVLAKSPVLRARKAWELPVEFLSPLAERCRK
QGIQFSCTPFYLQAVEELLPYVDFYKIASYELLWNDLLRACAATGKPVILSTGMATLDEIGGAVEMLRTAGCRDLTLLHC
VSGYPAPPEECNLAAIETIRSRFGCPVGWSDHSVSPAVIQRAVHQWEASAVEFHLDLEGEGEEFATGHCWLPDGIKAVIA
DVSTALSADGTGEKVPTPVEFPDREWRADPSDGLRPFLHVRNEWNG

Sequences:

>Translated_286_residues
MSSPLFVAEVSSNHHRDLERCFRFIDTAAAVGCGAVKFQLFRVEELFAPEVLAKSPVLRARKAWELPVEFLSPLAERCRK
QGIQFSCTPFYLQAVEELLPYVDFYKIASYELLWNDLLRACAATGKPVILSTGMATLDEIGGAVEMLRTAGCRDLTLLHC
VSGYPAPPEECNLAAIETIRSRFGCPVGWSDHSVSPAVIQRAVHQWEASAVEFHLDLEGEGEEFATGHCWLPDGIKAVIA
DVSTALSADGTGEKVPTPVEFPDREWRADPSDGLRPFLHVRNEWNG
>Mature_285_residues
SSPLFVAEVSSNHHRDLERCFRFIDTAAAVGCGAVKFQLFRVEELFAPEVLAKSPVLRARKAWELPVEFLSPLAERCRKQ
GIQFSCTPFYLQAVEELLPYVDFYKIASYELLWNDLLRACAATGKPVILSTGMATLDEIGGAVEMLRTAGCRDLTLLHCV
SGYPAPPEECNLAAIETIRSRFGCPVGWSDHSVSPAVIQRAVHQWEASAVEFHLDLEGEGEEFATGHCWLPDGIKAVIAD
VSTALSADGTGEKVPTPVEFPDREWRADPSDGLRPFLHVRNEWNG

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=225, Percent_Identity=26.2222222222222, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357081, Length=258, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31487

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPLFVAEVSSNHHRDLERCFRFIDTAAAVGCGAVKFQLFRVEELFAPEVLAKSPVLRA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
RKAWELPVEFLSPLAERCRKQGIQFSCTPFYLQAVEELLPYVDFYKIASYELLWNDLLRA
HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CAATGKPVILSTGMATLDEIGGAVEMLRTAGCRDLTLLHCVSGYPAPPEECNLAAIETIR
HHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
SRFGCPVGWSDHSVSPAVIQRAVHQWEASAVEFHLDLEGEGEEFATGHCWLPDGIKAVIA
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
DVSTALSADGTGEKVPTPVEFPDREWRADPSDGLRPFLHVRNEWNG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SSPLFVAEVSSNHHRDLERCFRFIDTAAAVGCGAVKFQLFRVEELFAPEVLAKSPVLRA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
RKAWELPVEFLSPLAERCRKQGIQFSCTPFYLQAVEELLPYVDFYKIASYELLWNDLLRA
HHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CAATGKPVILSTGMATLDEIGGAVEMLRTAGCRDLTLLHCVSGYPAPPEECNLAAIETIR
HHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
SRFGCPVGWSDHSVSPAVIQRAVHQWEASAVEFHLDLEGEGEEFATGHCWLPDGIKAVIA
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
DVSTALSADGTGEKVPTPVEFPDREWRADPSDGLRPFLHVRNEWNG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]