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The map label for this gene is flhF [H]

Identifier: 78221648

GI number: 78221648

Start: 474093

End: 475451

Strand: Direct

Name: flhF [H]

Synonym: Gmet_0427

Alternate gene names: 78221648

Gene position: 474093-475451 (Clockwise)

Preceding gene: 78221647

Following gene: 78221649

Centisome position: 11.86

GC content: 63.94

Gene sequence:

>1359_bases
ATGCTGGTTAAAACATTCGAAGCAGTGGACATGTCGGAGGCCCTCCGGAAGGTCAAGGCAGAGCTTGGCCCGGACGCCAT
GATCATCTCCTCGAAGAAGGAGAAGCGGGGGGGGATCCTCGGGTTTTTCTCCAAAGAGGTGGTGCAGGTGACCGCCGGCA
TCGAGATGAAGCCCCGGCAGCCGGCACCGAGCCAGAATCCCTACCGGGAGGCCCAGGAGGAGACCCTCTCCGCCAAGGAG
ATGATGGAGAACTCCATGCTGGGACCCCTGGCCCGGGAGCTGAAGGATCTGCGGGAGCGGGTCGAGGTCCTCACCCGCAA
GGAAACGGCCGCAAAGGCCCAGGCAGCGTCCCAGGTCTTGCCCGCCGCTCCTGTGGTGGAGAAGGTCGTTCCGTCACCCC
CCGCCGACTCCGTGCCCAAGACGATCCAGAAGCAGGACCTGGAGGAGATGAAGAAGCTCCTCTTCAAGACCCTGGCTGCC
AAGGAGGCCGGCGAGGGGGTAACCCCCGCCGAGAAGGCTGAAGTCCTTGCGAAGCCTGCGGCGGCTCCGGCCGACGGCGG
CAAGGGGGGCTTCAAGGGGACACTCCGGGTGATCATGAGCGAGCTGCACCGCAAAGGGCTGGAGCGGGGTTCGGTGCGGG
CGGTCATGGAGCAGGTGGAGCCCGAGGCCAAGAAGGGGGGGACCGTGGAGGCGCTCCGCTCATTCCTTCCCAATGCCTTC
ACCTCCGTCATCAAATGTGCCGGTCCCGTGGCCTTCAAGAAGAACAGCCCGCGGATCGTGGCCCTGGTGGGGCCTACGGG
GGTCGGCAAGACCACCACCATTGCCAAGCTGGCGGCCCACTACGCCCTACGGGAGAATCACCGGGCCGCCCTCATCACTA
TCGACAATTTTCGGGTCGGCGCGGTAGAGCAGCTCAAGACCTACTCACGCATCATGGGGGTTCCCGTGGAGGTGGCATCG
ACGCCTGCCGAACTGGAGGCGGCCATCGAGCTCCACTCCGACAAGGAGCTGATCCTCATCGATACGGCCGGCAGAAGCCA
CAAGGATAACGAGAAGATCGAGGAGCTGAAGGGATTCCTGGAGTCGCGGTTCGCCATCGAGATTCACCTCTGTCTCGCGG
CCACCACCCGTGACCGGGAGATCCTGGAGGTGGTGGAGCGGTTCGGCGTCCTCCCCATCTCCCGCGTCATCTTCACCAAG
CTGGACGAGAGCGAGAGCTACGGCACCATCGTCAACGCCCACCTCCGGACAAAGTTCCCGCTCTCTTACTTCACCACCGG
GCAACGGGTGCCCGAGGATCTTGAAATAGCAACGCCCGGCAGGGTAGCCGGGCTTGTCCTGGGGGAGATCAAGGAATGA

Upstream 100 bases:

>100_bases
AAGAAGCTCACCGAGCGGTTCGTCCCGAACCTGGCGGTGCTGTCGCACAACGAGATCCCGTCAAACGTCAAAATCCAATC
GTTAGGGGTGGTGACGCTCA

Downstream 100 bases:

>100_bases
ACGTCACGGCGACCACGGGAGATCAGGCAGACAGCCTCCGGCAGTTGGCCACCTCCGTAAACAAGAAGCGCAAGGCCTCG
GCGGCCCGTGCCCTTGAAGG

Product: GTP-binding signal recognition particle

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLVKTFEAVDMSEALRKVKAELGPDAMIISSKKEKRGGILGFFSKEVVQVTAGIEMKPRQPAPSQNPYREAQEETLSAKE
MMENSMLGPLARELKDLRERVEVLTRKETAAKAQAASQVLPAAPVVEKVVPSPPADSVPKTIQKQDLEEMKKLLFKTLAA
KEAGEGVTPAEKAEVLAKPAAAPADGGKGGFKGTLRVIMSELHRKGLERGSVRAVMEQVEPEAKKGGTVEALRSFLPNAF
TSVIKCAGPVAFKKNSPRIVALVGPTGVGKTTTIAKLAAHYALRENHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAS
TPAELEAAIELHSDKELILIDTAGRSHKDNEKIEELKGFLESRFAIEIHLCLAATTRDREILEVVERFGVLPISRVIFTK
LDESESYGTIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRVAGLVLGEIKE

Sequences:

>Translated_452_residues
MLVKTFEAVDMSEALRKVKAELGPDAMIISSKKEKRGGILGFFSKEVVQVTAGIEMKPRQPAPSQNPYREAQEETLSAKE
MMENSMLGPLARELKDLRERVEVLTRKETAAKAQAASQVLPAAPVVEKVVPSPPADSVPKTIQKQDLEEMKKLLFKTLAA
KEAGEGVTPAEKAEVLAKPAAAPADGGKGGFKGTLRVIMSELHRKGLERGSVRAVMEQVEPEAKKGGTVEALRSFLPNAF
TSVIKCAGPVAFKKNSPRIVALVGPTGVGKTTTIAKLAAHYALRENHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAS
TPAELEAAIELHSDKELILIDTAGRSHKDNEKIEELKGFLESRFAIEIHLCLAATTRDREILEVVERFGVLPISRVIFTK
LDESESYGTIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRVAGLVLGEIKE
>Mature_452_residues
MLVKTFEAVDMSEALRKVKAELGPDAMIISSKKEKRGGILGFFSKEVVQVTAGIEMKPRQPAPSQNPYREAQEETLSAKE
MMENSMLGPLARELKDLRERVEVLTRKETAAKAQAASQVLPAAPVVEKVVPSPPADSVPKTIQKQDLEEMKKLLFKTLAA
KEAGEGVTPAEKAEVLAKPAAAPADGGKGGFKGTLRVIMSELHRKGLERGSVRAVMEQVEPEAKKGGTVEALRSFLPNAF
TSVIKCAGPVAFKKNSPRIVALVGPTGVGKTTTIAKLAAHYALRENHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAS
TPAELEAAIELHSDKELILIDTAGRSHKDNEKIEELKGFLESRFAIEIHLCLAATTRDREILEVVERFGVLPISRVIFTK
LDESESYGTIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRVAGLVLGEIKE

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=202, Percent_Identity=30.6930693069307, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4507215, Length=202, Percent_Identity=30.6930693069307, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788963, Length=204, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789874, Length=218, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539958, Length=226, Percent_Identity=28.7610619469027, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17647949, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 49157; Mature: 49157

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVKTFEAVDMSEALRKVKAELGPDAMIISSKKEKRGGILGFFSKEVVQVTAGIEMKPRQ
CCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEHHHHHHHHHHCCCEECCCC
PAPSQNPYREAQEETLSAKEMMENSMLGPLARELKDLRERVEVLTRKETAAKAQAASQVL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAAPVVEKVVPSPPADSVPKTIQKQDLEEMKKLLFKTLAAKEAGEGVTPAEKAEVLAKPA
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
AAPADGGKGGFKGTLRVIMSELHRKGLERGSVRAVMEQVEPEAKKGGTVEALRSFLPNAF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHCHHH
TSVIKCAGPVAFKKNSPRIVALVGPTGVGKTTTIAKLAAHYALRENHRAALITIDNFRVG
HHHHHHCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AVEQLKTYSRIMGVPVEVASTPAELEAAIELHSDKELILIDTAGRSHKDNEKIEELKGFL
HHHHHHHHHHHHCCCHHHCCCCHHHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
ESRFAIEIHLCLAATTRDREILEVVERFGVLPISRVIFTKLDESESYGTIVNAHLRTKFP
HCCEEEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCEECC
LSYFTTGQRVPEDLEIATPGRVAGLVLGEIKE
HHHHCCCCCCCCCCEECCCCHHHHHHHHCCCC
>Mature Secondary Structure
MLVKTFEAVDMSEALRKVKAELGPDAMIISSKKEKRGGILGFFSKEVVQVTAGIEMKPRQ
CCCCCHHHCCHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEHHHHHHHHHHCCCEECCCC
PAPSQNPYREAQEETLSAKEMMENSMLGPLARELKDLRERVEVLTRKETAAKAQAASQVL
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAAPVVEKVVPSPPADSVPKTIQKQDLEEMKKLLFKTLAAKEAGEGVTPAEKAEVLAKPA
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
AAPADGGKGGFKGTLRVIMSELHRKGLERGSVRAVMEQVEPEAKKGGTVEALRSFLPNAF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHCHHH
TSVIKCAGPVAFKKNSPRIVALVGPTGVGKTTTIAKLAAHYALRENHRAALITIDNFRVG
HHHHHHCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AVEQLKTYSRIMGVPVEVASTPAELEAAIELHSDKELILIDTAGRSHKDNEKIEELKGFL
HHHHHHHHHHHHCCCHHHCCCCHHHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
ESRFAIEIHLCLAATTRDREILEVVERFGVLPISRVIFTKLDESESYGTIVNAHLRTKFP
HCCEEEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCEECC
LSYFTTGQRVPEDLEIATPGRVAGLVLGEIKE
HHHHCCCCCCCCCCEECCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]