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The map label for this gene is flhA

Identifier: 78221647

GI number: 78221647

Start: 472019

End: 474103

Strand: Direct

Name: flhA

Synonym: Gmet_0426

Alternate gene names: 78221647

Gene position: 472019-474103 (Clockwise)

Preceding gene: 78221646

Following gene: 78221648

Centisome position: 11.81

GC content: 64.08

Gene sequence:

>2085_bases
ATGGCACACCCGGCGGCCGGAGTTGTGGATCTTCAGCCAGCAAAAAGCAACTCGGACATCTACATGGCCGTGGCGCTCAT
CGGCGTCCTGGCCCTCATGATCGTGCCGCTGCCGGCGATCCTGCTCGATATCTTTCTCGCCGCCAACATCACCATCGCCC
TGGCGATCCTCCTGGTGGCCCTCTACACCCAGCAGCCCCTGGATTTCTCCGTCTTCCCGTCGGTACTCCTCGTCACTACC
CTCTACCGCCTCGCCCTGAACGTTGCCGGTACGCGGCTCATCCTCCTCCACGGCAACGAGGGGACCGACGCGGCCGGGCA
CGTGATCAAGGCCTTCGGCCAGTTCGTGGTGGGCGGAAACTTCGTGGTGGGGGCGGTCATCTTCCTGATCCTCGTCATCA
TCAACTTCACGGTCATCACCAAGGGCGCCGGCCGGGTGGCCGAGGTGGCGGCCCGCTTCACCCTGGACGCCATGCCCGGC
AAGCAGATGGCCATCGACGCCGACCTCTCCTCGGGACTCATCAACGAGAAGGAGGCCCGCCGCCGCCGGTCGCGGGTATC
GCGGGAGGCCGACTTCTACGGCTCCATGGACGGTGCCAGCAAGTTCGTGCGGGGGGACGCCATCGCCGGCATCCTCATCA
TGCTGGTGAACATCATCGGCGGGTTTGTCATCGGCGTCTGGCAGAACGGGATGCCCCTCGAAACGGCCCTGTCAAATTAT
ACGCTCCTGACCATCGGTGAGGGGCTCGTGGCCCAGATCCCGGCCCTCATCATCTCCACCGCCGCCGGCATCATCGTGAC
CCGCTCGGCCGACGAGAAGAATTTCGGCCACGAAATCACCGGTCAGTTCCTCAACTATCCCAAGGCCTTCTACGTCTCCT
CTGGGGTCCTCTTCGCCTTCGGCCTCATTCCGGGGCTTCCCCACTTCGCCTTCTTCCTCCTCTCGGGACTGGCCTACATG
GGGGGGCGCATGGCCAAGGAGGCTCCCCAGGTGATGGAGGAGGAACTGGCGGCCCTTCCTGCCGCAGCCGAGGCTGGAGA
GGGAGAGCAGGCGGCTATCCGCCCTCTGGACATGCTGGAGCTTGAGGTGGGATACGGGCTGGTTCCCATGGTGGATGCGG
CCCAGGAGGGTGAACTCCTGGAACGGATCCGCTCCATCCGCCGCCAGTACGCCCAGAAGATGGGGTTTGTGGTGCCGCCG
ATCCATATCCACGACAACCTGCAGCTGAAGCCCCACGAGTACAACGTCCTCATCAAGGGGGCCAAGGTGGGTGGTGGCGA
GCTGGCCGGCCAGTACCTGGCCATGGATTCCGGCGCCGTTGCCGCCCAGGTGGAAGGGGTGCGGACCACGGAGCCGGTCT
TTGGCCTGCCGGCCATCTGGATCAGGCCCGAGGTGAAGGAGCAGGCCCAACTCTACGGCTACACCGTGGTGGACAGCACC
ACGATCATCGCCACCCATATCAGCGAGATCATCAAGAAACATGCCCACGAGATGGTGGGGCGCCAGGAGCTCCAGCAGCT
CCTGGACAACCTCTCCTCCAGCTTCCCCAAGGTGGTGGACGAACTGGTGCCGAACCTCCTCAACCTGGGAACGGTGCTCC
GGGTCATCAAGAACCTCCTTCGCGAGGGAGTCTCCATCCGGGATCTGCGGACGATCCTGGAGACCCTGGCCGACTACGGC
GGGCTCACCAAGGACCCGGAGATGCTCACCGAGTTCACCCGCCAGGCCCTGGGGCGCTACATCGTCGACCAGTACAAGCG
GGACGACGAGACCCTCTGCATCATCAGTCTCGACCGCCGGGTGGAGGAGGTCGTGGCCGAAGGAATTCAGCCGTCGGAGC
AGGGGAGCTACCTGGCCATCGAGCCGAACACGGCCCAGGTGATCCTCTCCGGCATCCGGCAGGAGATCGAGAAGTTCAAC
CAGGCGGGGACCAACCCGACGCTTCTGGCGTCACCGTCCATCCGGCGGCACGTGAAGAAGCTCACCGAGCGGTTCGTCCC
GAACCTGGCGGTGCTGTCGCACAACGAGATCCCGTCAAACGTCAAAATCCAATCGTTAGGGGTGGTGACGCTCAATGCTG
GTTAA

Upstream 100 bases:

>100_bases
CCACGTTTTTCCCCTCATCTCCTTTTTCCATCTGGCACAACGGTTGCAGAATTATGGGTGCGCCCGAAAAGGGCTTGAAT
TTTCAAGGAGATTTTACCCT

Downstream 100 bases:

>100_bases
AACATTCGAAGCAGTGGACATGTCGGAGGCCCTCCGGAAGGTCAAGGCAGAGCTTGGCCCGGACGCCATGATCATCTCCT
CGAAGAAGGAGAAGCGGGGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MAHPAAGVVDLQPAKSNSDIYMAVALIGVLALMIVPLPAILLDIFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTT
LYRLALNVAGTRLILLHGNEGTDAAGHVIKAFGQFVVGGNFVVGAVIFLILVIINFTVITKGAGRVAEVAARFTLDAMPG
KQMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAIAGILIMLVNIIGGFVIGVWQNGMPLETALSNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEITGQFLNYPKAFYVSSGVLFAFGLIPGLPHFAFFLLSGLAYM
GGRMAKEAPQVMEEELAALPAAAEAGEGEQAAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPP
IHIHDNLQLKPHEYNVLIKGAKVGGGELAGQYLAMDSGAVAAQVEGVRTTEPVFGLPAIWIRPEVKEQAQLYGYTVVDST
TIIATHISEIIKKHAHEMVGRQELQQLLDNLSSSFPKVVDELVPNLLNLGTVLRVIKNLLREGVSIRDLRTILETLADYG
GLTKDPEMLTEFTRQALGRYIVDQYKRDDETLCIISLDRRVEEVVAEGIQPSEQGSYLAIEPNTAQVILSGIRQEIEKFN
QAGTNPTLLASPSIRRHVKKLTERFVPNLAVLSHNEIPSNVKIQSLGVVTLNAG

Sequences:

>Translated_694_residues
MAHPAAGVVDLQPAKSNSDIYMAVALIGVLALMIVPLPAILLDIFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTT
LYRLALNVAGTRLILLHGNEGTDAAGHVIKAFGQFVVGGNFVVGAVIFLILVIINFTVITKGAGRVAEVAARFTLDAMPG
KQMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAIAGILIMLVNIIGGFVIGVWQNGMPLETALSNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEITGQFLNYPKAFYVSSGVLFAFGLIPGLPHFAFFLLSGLAYM
GGRMAKEAPQVMEEELAALPAAAEAGEGEQAAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPP
IHIHDNLQLKPHEYNVLIKGAKVGGGELAGQYLAMDSGAVAAQVEGVRTTEPVFGLPAIWIRPEVKEQAQLYGYTVVDST
TIIATHISEIIKKHAHEMVGRQELQQLLDNLSSSFPKVVDELVPNLLNLGTVLRVIKNLLREGVSIRDLRTILETLADYG
GLTKDPEMLTEFTRQALGRYIVDQYKRDDETLCIISLDRRVEEVVAEGIQPSEQGSYLAIEPNTAQVILSGIRQEIEKFN
QAGTNPTLLASPSIRRHVKKLTERFVPNLAVLSHNEIPSNVKIQSLGVVTLNAG
>Mature_693_residues
AHPAAGVVDLQPAKSNSDIYMAVALIGVLALMIVPLPAILLDIFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTTL
YRLALNVAGTRLILLHGNEGTDAAGHVIKAFGQFVVGGNFVVGAVIFLILVIINFTVITKGAGRVAEVAARFTLDAMPGK
QMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAIAGILIMLVNIIGGFVIGVWQNGMPLETALSNYT
LLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEITGQFLNYPKAFYVSSGVLFAFGLIPGLPHFAFFLLSGLAYMG
GRMAKEAPQVMEEELAALPAAAEAGEGEQAAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPPI
HIHDNLQLKPHEYNVLIKGAKVGGGELAGQYLAMDSGAVAAQVEGVRTTEPVFGLPAIWIRPEVKEQAQLYGYTVVDSTT
IIATHISEIIKKHAHEMVGRQELQQLLDNLSSSFPKVVDELVPNLLNLGTVLRVIKNLLREGVSIRDLRTILETLADYGG
LTKDPEMLTEFTRQALGRYIVDQYKRDDETLCIISLDRRVEEVVAEGIQPSEQGSYLAIEPNTAQVILSGIRQEIEKFNQ
AGTNPTLLASPSIRRHVKKLTERFVPNLAVLSHNEIPSNVKIQSLGVVTLNAG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=662, Percent_Identity=48.7915407854985, Blast_Score=617, Evalue=1e-178,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75076; Mature: 74945

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPAAGVVDLQPAKSNSDIYMAVALIGVLALMIVPLPAILLDIFLAANITIALAILLVA
CCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTQQPLDFSVFPSVLLVTTLYRLALNVAGTRLILLHGNEGTDAAGHVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
FVVGAVIFLILVIINFTVITKGAGRVAEVAARFTLDAMPGKQMAIDADLSSGLINEKEAR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHH
RRRSRVSREADFYGSMDGASKFVRGDAIAGILIMLVNIIGGFVIGVWQNGMPLETALSNY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHCCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEITGQFLNYPKAFYVSSGVLFAF
EEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCCCHHHHCCHHHHHH
GLIPGLPHFAFFLLSGLAYMGGRMAKEAPQVMEEELAALPAAAEAGEGEQAAIRPLDMLE
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHCCCHHHHE
LEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPPIHIHDNLQLKPHEYNVLIKG
ECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEEEE
AKVGGGELAGQYLAMDSGAVAAQVEGVRTTEPVFGLPAIWIRPEVKEQAQLYGYTVVDST
CCCCCHHHCCHHEEECCCCCEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHCEEEECCC
TIIATHISEIIKKHAHEMVGRQELQQLLDNLSSSFPKVVDELVPNLLNLGTVLRVIKNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGVSIRDLRTILETLADYGGLTKDPEMLTEFTRQALGRYIVDQYKRDDETLCIISLDRR
HCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
VEEVVAEGIQPSEQGSYLAIEPNTAQVILSGIRQEIEKFNQAGTNPTLLASPSIRRHVKK
HHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
LTERFVPNLAVLSHNEIPSNVKIQSLGVVTLNAG
HHHHHCCCEEEEECCCCCCCCEEEEEEEEEECCC
>Mature Secondary Structure 
AHPAAGVVDLQPAKSNSDIYMAVALIGVLALMIVPLPAILLDIFLAANITIALAILLVA
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTQQPLDFSVFPSVLLVTTLYRLALNVAGTRLILLHGNEGTDAAGHVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
FVVGAVIFLILVIINFTVITKGAGRVAEVAARFTLDAMPGKQMAIDADLSSGLINEKEAR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHH
RRRSRVSREADFYGSMDGASKFVRGDAIAGILIMLVNIIGGFVIGVWQNGMPLETALSNY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHCCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEITGQFLNYPKAFYVSSGVLFAF
EEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCCCHHHHCCHHHHHH
GLIPGLPHFAFFLLSGLAYMGGRMAKEAPQVMEEELAALPAAAEAGEGEQAAIRPLDMLE
HHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHCCCHHHHE
LEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPPIHIHDNLQLKPHEYNVLIKG
ECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEEEE
AKVGGGELAGQYLAMDSGAVAAQVEGVRTTEPVFGLPAIWIRPEVKEQAQLYGYTVVDST
CCCCCHHHCCHHEEECCCCCEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHCEEEECCC
TIIATHISEIIKKHAHEMVGRQELQQLLDNLSSSFPKVVDELVPNLLNLGTVLRVIKNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGVSIRDLRTILETLADYGGLTKDPEMLTEFTRQALGRYIVDQYKRDDETLCIISLDRR
HCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
VEEVVAEGIQPSEQGSYLAIEPNTAQVILSGIRQEIEKFNQAGTNPTLLASPSIRRHVKK
HHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
LTERFVPNLAVLSHNEIPSNVKIQSLGVVTLNAG
HHHHHCCCEEEEECCCCCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]