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The map label for this gene is hycD [H]

Identifier: 78221595

GI number: 78221595

Start: 417638

End: 418546

Strand: Reverse

Name: hycD [H]

Synonym: Gmet_0374

Alternate gene names: 78221595

Gene position: 418546-417638 (Counterclockwise)

Preceding gene: 78221596

Following gene: 78221594

Centisome position: 10.47

GC content: 66.56

Gene sequence:

>909_bases
ATGGTCGACGCCGTTATCCATATCCTGATTACCCTGCTCATGCCGCCGCTGCTGCTCGGGGTGATCAACCGGACCAAGGC
CATCTTTGCAGGCCGCACCGGTCCACCGCTTTTTCAAGCGTACTACGACCTGGCAAAGCTCGTGCGCAAGGGGTCGGTCT
TCAGCGAAACCACGAGCTGGGTCTTCCGGGCGGGACCAGTGGCGGGCCTGGCGGCAACGCTTGTGGCCTCGCTCCTGATC
CCCCTCGGGGAGCACCGCCCCCCTCTCTCTTTCAGCGGCGACATGATCCTCTTCGCCTATCTCTTCGGGCTGGCCCGCTT
CTGCACCACGGCGGCGGCCCTGGATACCGGTTCCAGCTTCGAGGGGATGGGGGCGGCCCGGGAGGCCACCTTCGCCTGCC
TGGCCGAGCCGGCCCTCTTCTTCTCCCTGGCGGTGCTGGCACGGCTCTCCGGCTCCCTCTCCCTGACCCCCATGCTGACC
GGGACTGCCGCCACCTCCTGGCTTTCGGCCGGCGCATCGCTCCTCCTGCTGGTGGGAAGCCTCTTCATCGTGCTCCTGGC
CGAGAACTGCCGGGTCCCTTTCGACGACCCCACCACCCACCTGGAACTGACCATGATCCACGAGGTGATGGTGCTCGACC
ACAGCGGCCCCCTCTTCGGCGCCATCCTCTACGGGGCGGCCCTGAAACTCTTCGTGCTGGGTGCCCTGTTCACCGACATC
GCCCTCCCCTATGCCACCGGCATCCCCGTGGTGGACTGGGTCCTCTTCGTGATCGCCATGATGATGCTGGCCGTGGGGAT
CGGCATGGTGGAATCGGTCATGGCACGGCTGCGGCTCCCCAAGGTCCCCCAGATGCTGGCGGCGGCCTGCATCCTGGCGG
CGTTTTCGCTGCTCCTGGTGCTGAGGTAG

Upstream 100 bases:

>100_bases
CCGCAAGCTCCAGCACGGCCGGCTCCACCTTTATATCCTCTACATCTTCGTGACGCTGGCGCTCTTGCTGGCGTGGGCCT
ATTAAAGGAGCAGGAAGGGA

Downstream 100 bases:

>100_bases
ACCATGACTTCCCTGGTGGACCAGCTCATCGTCCTCGTGATGCTCATCAACTTCGCGGCCCTCGGTTCGGGGCGCCTGGC
CGTGGCGATCCGCGCCGTGG

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVDAVIHILITLLMPPLLLGVINRTKAIFAGRTGPPLFQAYYDLAKLVRKGSVFSETTSWVFRAGPVAGLAATLVASLLI
PLGEHRPPLSFSGDMILFAYLFGLARFCTTAAALDTGSSFEGMGAAREATFACLAEPALFFSLAVLARLSGSLSLTPMLT
GTAATSWLSAGASLLLLVGSLFIVLLAENCRVPFDDPTTHLELTMIHEVMVLDHSGPLFGAILYGAALKLFVLGALFTDI
ALPYATGIPVVDWVLFVIAMMMLAVGIGMVESVMARLRLPKVPQMLAAACILAAFSLLLVLR

Sequences:

>Translated_302_residues
MVDAVIHILITLLMPPLLLGVINRTKAIFAGRTGPPLFQAYYDLAKLVRKGSVFSETTSWVFRAGPVAGLAATLVASLLI
PLGEHRPPLSFSGDMILFAYLFGLARFCTTAAALDTGSSFEGMGAAREATFACLAEPALFFSLAVLARLSGSLSLTPMLT
GTAATSWLSAGASLLLLVGSLFIVLLAENCRVPFDDPTTHLELTMIHEVMVLDHSGPLFGAILYGAALKLFVLGALFTDI
ALPYATGIPVVDWVLFVIAMMMLAVGIGMVESVMARLRLPKVPQMLAAACILAAFSLLLVLR
>Mature_302_residues
MVDAVIHILITLLMPPLLLGVINRTKAIFAGRTGPPLFQAYYDLAKLVRKGSVFSETTSWVFRAGPVAGLAATLVASLLI
PLGEHRPPLSFSGDMILFAYLFGLARFCTTAAALDTGSSFEGMGAAREATFACLAEPALFFSLAVLARLSGSLSLTPMLT
GTAATSWLSAGASLLLLVGSLFIVLLAENCRVPFDDPTTHLELTMIHEVMVLDHSGPLFGAILYGAALKLFVLGALFTDI
ALPYATGIPVVDWVLFVIAMMMLAVGIGMVESVMARLRLPKVPQMLAAACILAAFSLLLVLR

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=290, Percent_Identity=32.7586206896552, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082115, Length=242, Percent_Identity=33.0578512396694, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 32015; Mature: 32015

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDAVIHILITLLMPPLLLGVINRTKAIFAGRTGPPLFQAYYDLAKLVRKGSVFSETTSW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VFRAGPVAGLAATLVASLLIPLGEHRPPLSFSGDMILFAYLFGLARFCTTAAALDTGSSF
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
EGMGAAREATFACLAEPALFFSLAVLARLSGSLSLTPMLTGTAATSWLSAGASLLLLVGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LFIVLLAENCRVPFDDPTTHLELTMIHEVMVLDHSGPLFGAILYGAALKLFVLGALFTDI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALPYATGIPVVDWVLFVIAMMMLAVGIGMVESVMARLRLPKVPQMLAAACILAAFSLLLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LR
CC
>Mature Secondary Structure
MVDAVIHILITLLMPPLLLGVINRTKAIFAGRTGPPLFQAYYDLAKLVRKGSVFSETTSW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VFRAGPVAGLAATLVASLLIPLGEHRPPLSFSGDMILFAYLFGLARFCTTAAALDTGSSF
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
EGMGAAREATFACLAEPALFFSLAVLARLSGSLSLTPMLTGTAATSWLSAGASLLLLVGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LFIVLLAENCRVPFDDPTTHLELTMIHEVMVLDHSGPLFGAILYGAALKLFVLGALFTDI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALPYATGIPVVDWVLFVIAMMMLAVGIGMVESVMARLRLPKVPQMLAAACILAAFSLLLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]