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The map label for this gene is ftsK [H]

Identifier: 78221588

GI number: 78221588

Start: 409721

End: 412003

Strand: Direct

Name: ftsK [H]

Synonym: Gmet_0367

Alternate gene names: 78221588

Gene position: 409721-412003 (Clockwise)

Preceding gene: 78221587

Following gene: 78221589

Centisome position: 10.25

GC content: 61.59

Gene sequence:

>2283_bases
ATGGACGAACAGATCGACAAGAAAGAAAAACTGAAGAAGGAGATCCAGGGGATGGCCCTCGGCGCGCTGGGGCTCTTCAT
CCTCATTGCCCTTGTGTCGTTCAATGCCGGCGACCCCTCGTCAAATACGTACAATTCCGAAACAGGGGTTCACAATTTCG
GCGGCAGATTGGGAGCGGAGCTTTCCGACCTTCTCATCCAGATCGTTGGGCTTGCCTCTTATGCTGTCCCAACGGGTCTG
CTGTATCTTTCGTACAAACTTCTCCGCTTTAAGGAGTTGCGTTGGAAAAATTATAAAGCGTTTGCCTTTATTACGCTGTT
GATCTCATTGTCGTCGTTGTTCGGATTTTTTAAGCCCGACACGGTCTTTCTTGGTCAAAAAGTCCTCACCGGCGGTGCCG
TTGGGACTAAGACGGCAACGTTCCTCAAGACCTACTTCGGCATCCCCGGAGCCATCCTTATCATCCTCCCCCTCCTGGCC
GCTTCGGCCATGGTCCTGTCCCGCTTCTCCTTCGTCCTCTTCGCCGACTGGTGGTTCGCGAACCTGAAGGAGCGCTGGGC
CCGACGTCGGGAGCGGCAGGAGCTGAACCGCCAGCTCCTCGATACGGGGGAGAAGGCCGAGAAGAAAAAATCACCGGAAA
TCAAGCCGGTCCACGTGGCGGTTCCCCCTCCGCCGCCGGTCCAGAAAAAAGAGGAGAAGAAGGAAAAGGCCAAGATCGCC
CCACTCCAGGAGGCCTTCGACTTCATCAAGGCGGAGGGGGACCACCGCACTCCGCCGCTCTCGCTCCTCGATACCCCTCC
CCAGACCGAGAAGCGCCTCGACCGCGACATCCTCACCATGAACGCCCGGCTTCTGGAGAAGAAGTTCAAGGATTTCGGCA
TCGACGGCGAGGTGGTGGAGATCTGCCCCGGCCCGGTGATCACCATGTTCGAGTTCGCCCCGGGCCCCGGCATCAAGGTG
AGTCGCATAGCCTCCCTCTCCGACGACCTCTCCATGGCGCTCCAGTCCATGTCGATCCGGATCGTGGCCCCCATTCCCGG
CAAGGGGGTGGTGGGGATCGAGATCCCGAACCGGGAGCGGGAGACGGTCTTTCTTAAGGAGATTTTCAACGGCGAGGAGT
TCCACGGCAGCAAGATGAAGCTGCCGCTCGCTCTCGGCAAAGACATCGCCGGCGCCCCGGTCGTGACCGATCTGGCCAAA
ATGCCCCACCTCCTGGTGGCCGGCGCCACCGGATCGGGAAAGTCCGTATCCATCAACACCATGATCCTGTCGCTCCTCTA
TACCGCTACCCCCAAGGACGTGCGGGTCATCATGGTGGACCCGAAGATGCTGGAACTTTCCATCTACGAGGGGATCCCGC
ACCTGCTTCTTCCCGTTGTCACCAACCCCAAGAAGGCATCCCTGGCGCTGAAGTGGGCCGTGGAGGAGATGGGGCGTCGC
TACCGCCTCATGGCCGACAAGGGGGTGCGGAACATCGGCTCCTACAACCAGTGCCTCGAAAAGGAGGAGAAGGAGGCCGA
GGAGCTCAAGGCCCAGGGGACCGTTGTGCTGGAAGACGTGGTGGACGAGTCCCCGGACGACGAGGAGGCGATCCAGCAGT
TCCTGGCCAAGCAGGAGGAGCTGGAGCACGGGCACCTGCCGTACATCGTCGTCATCGTGGACGAACTGGCGGACCTCATG
ATGGTGGCCGGCCGGGAGATCGAGGAGTCCATCGCACGCCTGGCCCAGATGGCCCGGGCCGCCGGCATCCATCTCATCCT
CGCCACGCAGCGGCCGTCGGTGGACGTCATCACCGGCCTCATCAAGGCCAACTTCCCGGCCCGGATCTCCTTCCAGGTCT
CCTCCAAAATCGACTCCCGGACCATCCTCGACACCAACGGCGCCGAGTCGCTCCTGGGGGCCGGCGACATGCTCTTCCTT
CCCCCGGGAACCGCCAAGATGCAGCGGGTCCACGGGGCCTTCGTTTCCGACGCCGAGGTGCAGCGGGTGGTGGACTTCCT
CAAGAAGCAGGGGAAGCCGGTCTACGACAAGTCGATCCTGGAGATGAAGGAAGAGAGCGGCTCCGGCAGCGGCGACGACG
AGGATATGGTGGACGAGCGGTACGATGACGCCGTGGCCCTGGTGGCCGAGACGCGCCAGGCCTCCATCTCCATGGTCCAG
CGGCGGCTGCGGATCGGCTACAACCGCGCCGCGAGAATCATCGAGCGGATGGAGCAGGAGGGGATCGTCGGCCCAAGCGA
CGGGACCAGCAAGCCACGGGAAGTCTTCATCAACAAGATCTGA

Upstream 100 bases:

>100_bases
ACGAGGTGAAGCAGGAAGTGCGGCGCATCCTGAGACGTTTCTTCAACAAGACCATTGAGCGGCGGCCAGTGATCCTGCCG
CTGATTATAGAGATGTAGGA

Downstream 100 bases:

>100_bases
GCCGTCATGACAGAGTACCCTCTCCCCCTTTTTATCCTCAATCTCATCCTCACCCTTGTCGATGCCGCCATCGGCTACCA
CGTGGCGCCGATGATCATGC

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MDEQIDKKEKLKKEIQGMALGALGLFILIALVSFNAGDPSSNTYNSETGVHNFGGRLGAELSDLLIQIVGLASYAVPTGL
LYLSYKLLRFKELRWKNYKAFAFITLLISLSSLFGFFKPDTVFLGQKVLTGGAVGTKTATFLKTYFGIPGAILIILPLLA
ASAMVLSRFSFVLFADWWFANLKERWARRRERQELNRQLLDTGEKAEKKKSPEIKPVHVAVPPPPPVQKKEEKKEKAKIA
PLQEAFDFIKAEGDHRTPPLSLLDTPPQTEKRLDRDILTMNARLLEKKFKDFGIDGEVVEICPGPVITMFEFAPGPGIKV
SRIASLSDDLSMALQSMSIRIVAPIPGKGVVGIEIPNRERETVFLKEIFNGEEFHGSKMKLPLALGKDIAGAPVVTDLAK
MPHLLVAGATGSGKSVSINTMILSLLYTATPKDVRVIMVDPKMLELSIYEGIPHLLLPVVTNPKKASLALKWAVEEMGRR
YRLMADKGVRNIGSYNQCLEKEEKEAEELKAQGTVVLEDVVDESPDDEEAIQQFLAKQEELEHGHLPYIVVIVDELADLM
MVAGREIEESIARLAQMARAAGIHLILATQRPSVDVITGLIKANFPARISFQVSSKIDSRTILDTNGAESLLGAGDMLFL
PPGTAKMQRVHGAFVSDAEVQRVVDFLKKQGKPVYDKSILEMKEESGSGSGDDEDMVDERYDDAVALVAETRQASISMVQ
RRLRIGYNRAARIIERMEQEGIVGPSDGTSKPREVFINKI

Sequences:

>Translated_760_residues
MDEQIDKKEKLKKEIQGMALGALGLFILIALVSFNAGDPSSNTYNSETGVHNFGGRLGAELSDLLIQIVGLASYAVPTGL
LYLSYKLLRFKELRWKNYKAFAFITLLISLSSLFGFFKPDTVFLGQKVLTGGAVGTKTATFLKTYFGIPGAILIILPLLA
ASAMVLSRFSFVLFADWWFANLKERWARRRERQELNRQLLDTGEKAEKKKSPEIKPVHVAVPPPPPVQKKEEKKEKAKIA
PLQEAFDFIKAEGDHRTPPLSLLDTPPQTEKRLDRDILTMNARLLEKKFKDFGIDGEVVEICPGPVITMFEFAPGPGIKV
SRIASLSDDLSMALQSMSIRIVAPIPGKGVVGIEIPNRERETVFLKEIFNGEEFHGSKMKLPLALGKDIAGAPVVTDLAK
MPHLLVAGATGSGKSVSINTMILSLLYTATPKDVRVIMVDPKMLELSIYEGIPHLLLPVVTNPKKASLALKWAVEEMGRR
YRLMADKGVRNIGSYNQCLEKEEKEAEELKAQGTVVLEDVVDESPDDEEAIQQFLAKQEELEHGHLPYIVVIVDELADLM
MVAGREIEESIARLAQMARAAGIHLILATQRPSVDVITGLIKANFPARISFQVSSKIDSRTILDTNGAESLLGAGDMLFL
PPGTAKMQRVHGAFVSDAEVQRVVDFLKKQGKPVYDKSILEMKEESGSGSGDDEDMVDERYDDAVALVAETRQASISMVQ
RRLRIGYNRAARIIERMEQEGIVGPSDGTSKPREVFINKI
>Mature_760_residues
MDEQIDKKEKLKKEIQGMALGALGLFILIALVSFNAGDPSSNTYNSETGVHNFGGRLGAELSDLLIQIVGLASYAVPTGL
LYLSYKLLRFKELRWKNYKAFAFITLLISLSSLFGFFKPDTVFLGQKVLTGGAVGTKTATFLKTYFGIPGAILIILPLLA
ASAMVLSRFSFVLFADWWFANLKERWARRRERQELNRQLLDTGEKAEKKKSPEIKPVHVAVPPPPPVQKKEEKKEKAKIA
PLQEAFDFIKAEGDHRTPPLSLLDTPPQTEKRLDRDILTMNARLLEKKFKDFGIDGEVVEICPGPVITMFEFAPGPGIKV
SRIASLSDDLSMALQSMSIRIVAPIPGKGVVGIEIPNRERETVFLKEIFNGEEFHGSKMKLPLALGKDIAGAPVVTDLAK
MPHLLVAGATGSGKSVSINTMILSLLYTATPKDVRVIMVDPKMLELSIYEGIPHLLLPVVTNPKKASLALKWAVEEMGRR
YRLMADKGVRNIGSYNQCLEKEEKEAEELKAQGTVVLEDVVDESPDDEEAIQQFLAKQEELEHGHLPYIVVIVDELADLM
MVAGREIEESIARLAQMARAAGIHLILATQRPSVDVITGLIKANFPARISFQVSSKIDSRTILDTNGAESLLGAGDMLFL
PPGTAKMQRVHGAFVSDAEVQRVVDFLKKQGKPVYDKSILEMKEESGSGSGDDEDMVDERYDDAVALVAETRQASISMVQ
RRLRIGYNRAARIIERMEQEGIVGPSDGTSKPREVFINKI

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=502, Percent_Identity=54.3824701195219, Blast_Score=506, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83950; Mature: 83950

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQIDKKEKLKKEIQGMALGALGLFILIALVSFNAGDPSSNTYNSETGVHNFGGRLGAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCHHHHH
LSDLLIQIVGLASYAVPTGLLYLSYKLLRFKELRWKNYKAFAFITLLISLSSLFGFFKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
TVFLGQKVLTGGAVGTKTATFLKTYFGIPGAILIILPLLAASAMVLSRFSFVLFADWWFA
CEECCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLKERWARRRERQELNRQLLDTGEKAEKKKSPEIKPVHVAVPPPPPVQKKEEKKEKAKIA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCC
PLQEAFDFIKAEGDHRTPPLSLLDTPPQTEKRLDRDILTMNARLLEKKFKDFGIDGEVVE
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ICPGPVITMFEFAPGPGIKVSRIASLSDDLSMALQSMSIRIVAPIPGKGVVGIEIPNRER
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCC
ETVFLKEIFNGEEFHGSKMKLPLALGKDIAGAPVVTDLAKMPHLLVAGATGSGKSVSINT
HHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEHHH
MILSLLYTATPKDVRVIMVDPKMLELSIYEGIPHLLLPVVTNPKKASLALKWAVEEMGRR
HHHHHHHHCCCCCEEEEEECCCEEEEEHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCHH
YRLMADKGVRNIGSYNQCLEKEEKEAEELKAQGTVVLEDVVDESPDDEEAIQQFLAKQEE
EEHHHHHCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCHHHHHHHHHHHHHH
LEHGHLPYIVVIVDELADLMMVAGREIEESIARLAQMARAAGIHLILATQRPSVDVITGL
HCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANFPARISFQVSSKIDSRTILDTNGAESLLGAGDMLFLPPGTAKMQRVHGAFVSDAEV
HHCCCCCEEEEEECCCCCCCEEECCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHHH
QRVVDFLKKQGKPVYDKSILEMKEESGSGSGDDEDMVDERYDDAVALVAETRQASISMVQ
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHH
RRLRIGYNRAARIIERMEQEGIVGPSDGTSKPREVFINKI
HHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MDEQIDKKEKLKKEIQGMALGALGLFILIALVSFNAGDPSSNTYNSETGVHNFGGRLGAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCHHHHH
LSDLLIQIVGLASYAVPTGLLYLSYKLLRFKELRWKNYKAFAFITLLISLSSLFGFFKPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
TVFLGQKVLTGGAVGTKTATFLKTYFGIPGAILIILPLLAASAMVLSRFSFVLFADWWFA
CEECCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLKERWARRRERQELNRQLLDTGEKAEKKKSPEIKPVHVAVPPPPPVQKKEEKKEKAKIA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHCCC
PLQEAFDFIKAEGDHRTPPLSLLDTPPQTEKRLDRDILTMNARLLEKKFKDFGIDGEVVE
CHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ICPGPVITMFEFAPGPGIKVSRIASLSDDLSMALQSMSIRIVAPIPGKGVVGIEIPNRER
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCC
ETVFLKEIFNGEEFHGSKMKLPLALGKDIAGAPVVTDLAKMPHLLVAGATGSGKSVSINT
HHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEHHH
MILSLLYTATPKDVRVIMVDPKMLELSIYEGIPHLLLPVVTNPKKASLALKWAVEEMGRR
HHHHHHHHCCCCCEEEEEECCCEEEEEHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHCHH
YRLMADKGVRNIGSYNQCLEKEEKEAEELKAQGTVVLEDVVDESPDDEEAIQQFLAKQEE
EEHHHHHCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCHHHHHHHHHHHHHH
LEHGHLPYIVVIVDELADLMMVAGREIEESIARLAQMARAAGIHLILATQRPSVDVITGL
HCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANFPARISFQVSSKIDSRTILDTNGAESLLGAGDMLFLPPGTAKMQRVHGAFVSDAEV
HHCCCCCEEEEEECCCCCCCEEECCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHHH
QRVVDFLKKQGKPVYDKSILEMKEESGSGSGDDEDMVDERYDDAVALVAETRQASISMVQ
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHH
RRLRIGYNRAARIIERMEQEGIVGPSDGTSKPREVFINKI
HHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]