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The map label for this gene is aroF [H]

Identifier: 78221567

GI number: 78221567

Start: 384597

End: 385616

Strand: Direct

Name: aroF [H]

Synonym: Gmet_0346

Alternate gene names: 78221567

Gene position: 384597-385616 (Clockwise)

Preceding gene: 78221563

Following gene: 78221568

Centisome position: 9.62

GC content: 63.53

Gene sequence:

>1020_bases
ATGATCATCGTCATGAAAGCAGGTGCAGCGAAAAAGGACCGGGACGAGGTAATCAAGCGGATCAAGGAGCTGGGGTACAA
GCCCCACGTGATCCACGGAACCACGCGGGACGTGATCGGGGCCGTGGGGGACGAGCGGGGGAAGCTGGTGCTGCAATCGA
TCGAATCGATGCACGGGGTGGAGAGCGTGGTCCCGATCCTCAAGCCCTACAAACTCGCCTCCAAGGAGGTGAAGGTGGAG
CCGAGCATCATCCGGATCAGCGATGCGGTGAGCATCGGCGGCAAGGAGATCATCGTCATGGCCGGCCCCTGTTCGGTGGA
AGGGGAGGAGCAGATCATCGAGACGGCCAAGGCGGTGAAGGCCGCCGGCGCCCAGGTGCTCCGCGGTGGGGCGTTCAAGC
CGCGCACCTCCCCGTACTCCTTCCAGGGCCTTGAGGAAGAAGGACTCAAGCTTCTGGCCAAGGCCCGGGAGATCACCGGC
CTTCCCATCGTTACCGAGGTGGTGAATCCCGAGACGGCGGATCTCGTGGCCGAGTACTCTGACATCCTCCAGATCGGCGC
CCGCAATGCCCAGAACTTCGCCCTGCTCAAGAAGGTCGGGCAGCTCAGGCGGCCGGTACTCCTCAAGCGGGGCATGTCCA
TGACCATCCAGGAGTTCCTCATGAGCGCCGAGTACGTCTTGAGCGAGGGGAACCAGTCGGTGATCCTCTGCGAGCGGGGA
ATCCGCACCTTCGAGACGGCAACTCGCAATACCCTTGACCTCTCCGCCATCCCGGTCCTCAAGGGGATGACGCACCTGCC
GGTCATTGCCGACCCCTCCCACGGTACCGGTAACTACCACTACGTGGCCCCCATGGCGCTGGCCGCCGTTGCCGCCGGGG
CCGACGGGCTAATGATCGAGGTGCATCCCGATCCGGAACGGGCCTCGTCGGACGGTCCCCAGTCCCTCAAGCCCAAGAAG
TTCGATGCCCTCATGACGAAACTCAGGCTCGTTGCCGAGTCCGTGGACCGGATTGTCTAG

Upstream 100 bases:

>100_bases
ACCCCCGGCTTTTTCAGTTGTTAAGACCAATATCGTGACAGTCAAAGGCCGGGGGAAATCCTCCGGCCTTTCGTCTTTCC
GGGACCACAGGGAGGAAAGG

Downstream 100 bases:

>100_bases
CAAACGGTCGAGCAAAACCCTTGCGCCCTTCCCGATGCTGCGATAGGATTGGTTGTTTTTAACCATGGTGGACAGCACAA
GCTGAGGGAGGGGTACATGC

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIIVMKAGAAKKDRDEVIKRIKELGYKPHVIHGTTRDVIGAVGDERGKLVLQSIESMHGVESVVPILKPYKLASKEVKVE
PSIIRISDAVSIGGKEIIVMAGPCSVEGEEQIIETAKAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREITG
LPIVTEVVNPETADLVAEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVLSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMTKLRLVAESVDRIV

Sequences:

>Translated_339_residues
MIIVMKAGAAKKDRDEVIKRIKELGYKPHVIHGTTRDVIGAVGDERGKLVLQSIESMHGVESVVPILKPYKLASKEVKVE
PSIIRISDAVSIGGKEIIVMAGPCSVEGEEQIIETAKAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREITG
LPIVTEVVNPETADLVAEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVLSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMTKLRLVAESVDRIV
>Mature_339_residues
MIIVMKAGAAKKDRDEVIKRIKELGYKPHVIHGTTRDVIGAVGDERGKLVLQSIESMHGVESVVPILKPYKLASKEVKVE
PSIIRISDAVSIGGKEIIVMAGPCSVEGEEQIIETAKAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREITG
LPIVTEVVNPETADLVAEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVLSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKGMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMTKLRLVAESVDRIV

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=212, Percent_Identity=28.7735849056604, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36575; Mature: 36575

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVMKAGAAKKDRDEVIKRIKELGYKPHVIHGTTRDVIGAVGDERGKLVLQSIESMHGV
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHH
ESVVPILKPYKLASKEVKVEPSIIRISDAVSIGGKEIIVMAGPCSVEGEEQIIETAKAVK
HHHHHHHCCHHHCCCCEECCCCEEEEECHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREITGLPIVTEVVNPETADLVAEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCHHHHHHHHH
DILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVLSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKGMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIE
CHHHHHHCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEE
VHPDPERASSDGPQSLKPKKFDALMTKLRLVAESVDRIV
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIVMKAGAAKKDRDEVIKRIKELGYKPHVIHGTTRDVIGAVGDERGKLVLQSIESMHGV
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHH
ESVVPILKPYKLASKEVKVEPSIIRISDAVSIGGKEIIVMAGPCSVEGEEQIIETAKAVK
HHHHHHHCCHHHCCCCEECCCCEEEEECHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREITGLPIVTEVVNPETADLVAEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCHHHHHHHHH
DILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVLSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKGMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIE
CHHHHHHCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEE
VHPDPERASSDGPQSLKPKKFDALMTKLRLVAESVDRIV
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]