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The map label for this gene is cinA [C]

Identifier: 78221420

GI number: 78221420

Start: 226180

End: 227421

Strand: Direct

Name: cinA [C]

Synonym: Gmet_0196

Alternate gene names: 78221420

Gene position: 226180-227421 (Clockwise)

Preceding gene: 78221419

Following gene: 78221421

Centisome position: 5.66

GC content: 67.79

Gene sequence:

>1242_bases
GTGAAAACGGCGCTTCTCTCCATCGGCGACGAACTCCTCCTTGGTGAGGTTGTGGATACCAACTCGGCTCGAATCGCAGC
ACGGCTGGCCGACGAGGGGATCGTCACGGCCCGGAAACTGACCGTGGGGGATGACGAGGGGGAAATCGCCGGGGCCCTGG
AGGAGCTTGCCCGTGGTCACGACGTGGTCATCGCCACGGGAGGCCTCGGCCCCACCGATGACGACGTGACCGCCCGGGCC
GCTGCCCGGGCCACGGGAAGGCGCCTCGTCCTGAACGAGGAGGCCATGGGGCACCTCAGGGAGTTTTTCGTCCGGCTGGG
GCGGGAGATGCACCCGGCCAACGGCCGCCAGTGCCTTCTGCCGGCCAAGGCGGAACTCATCCCGAATCCCACCGGCACTG
CCAGCGGTTTTTATCTCCCCCTCGACAGATGTCTCCTCATGTTCCTCCCCGGGGTCCCCTCCGAGATGGCCGTGATGCTG
GATGAGACGGTTGTTCCCCTGGTTCTGGAGCGGCGCGGGGAGCACCGGCGCACCCGAACTTTGACCCTTACGGTCTTCGG
CCTCTCCGAGGCGGAGATCGGCGCCCGCCTCTCGGACTTGGACCGCTCACGGCCGGGGCTTACGGTCGCCTACTGCGTGG
AGTATCCGGTGGTTCAGGTGAAGCTCCGGGCCACAGGGGAGGACGAGGGGGCGCTGACGGCGCTTCTGGAGGACGGTGCG
GCCCTGGTGCGGGAACGTCTCGGGGGGCACGTGGTCGCCGGGGACGGGGAAACCATCGACACAACAGTGGCCCGCCTCTT
CCGGGAAACGGGGATGACCCTGGCCCTGGCCGAGTCGTGTACCGGCGGCCTCATCGCCGGACGGGTCACGGCGATTCCCG
GCAGTTCCGCCTATTTTTTCCTCAGCGCGGTCACCTATGCCAACGACGCCAAGGCGCGTCTGCTTGGCGTTCCCCAGGGG
CTTCTGGCCGAGACCGGGGCCGTGAGCGCCGAGGTGGCCAAGGCCATGGCCCGGGGGGCGCGGCAACTGGCCGGGAGCGA
TCTGGCCCTGGCCGTTACCGGCATCGCCGGGCCGGAGGGGGGGAGCCCGGACAAGCCAGTGGGGACGGTGTTCATCGCCT
TGGCGGACCAGGCAGGTTGCTCTGCCAAGGGGTACCATTTCAGGGGAGACCGCGACAGGATCAGGACGATCACCGCGGTT
ACGGCCATGGATTGGCTGAGAAGGCGGCTTTTATCACATTAG

Upstream 100 bases:

>100_bases
ACTTCGACCGGCAGGTGAAAAACGGTTACGGCGTGGTCCTCGATGACGTGGTGGCCGGCATCTACGCCTGCGTGGTGCTC
CACGTGATCCTGAGGTTTCT

Downstream 100 bases:

>100_bases
TCCTTGGCGGGATGGATAGGTAGTCATGTCTTCACCAAACCATCGGATATGCCTCGTTGTCGGCTGGGGGGGCGCCGTTC
TGCTCTTCCTGGGGCTTGTC

Product: competence/damage-inducible protein cinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKTALLSIGDELLLGEVVDTNSARIAARLADEGIVTARKLTVGDDEGEIAGALEELARGHDVVIATGGLGPTDDDVTARA
AARATGRRLVLNEEAMGHLREFFVRLGREMHPANGRQCLLPAKAELIPNPTGTASGFYLPLDRCLLMFLPGVPSEMAVML
DETVVPLVLERRGEHRRTRTLTLTVFGLSEAEIGARLSDLDRSRPGLTVAYCVEYPVVQVKLRATGEDEGALTALLEDGA
ALVRERLGGHVVAGDGETIDTTVARLFRETGMTLALAESCTGGLIAGRVTAIPGSSAYFFLSAVTYANDAKARLLGVPQG
LLAETGAVSAEVAKAMARGARQLAGSDLALAVTGIAGPEGGSPDKPVGTVFIALADQAGCSAKGYHFRGDRDRIRTITAV
TAMDWLRRRLLSH

Sequences:

>Translated_413_residues
MKTALLSIGDELLLGEVVDTNSARIAARLADEGIVTARKLTVGDDEGEIAGALEELARGHDVVIATGGLGPTDDDVTARA
AARATGRRLVLNEEAMGHLREFFVRLGREMHPANGRQCLLPAKAELIPNPTGTASGFYLPLDRCLLMFLPGVPSEMAVML
DETVVPLVLERRGEHRRTRTLTLTVFGLSEAEIGARLSDLDRSRPGLTVAYCVEYPVVQVKLRATGEDEGALTALLEDGA
ALVRERLGGHVVAGDGETIDTTVARLFRETGMTLALAESCTGGLIAGRVTAIPGSSAYFFLSAVTYANDAKARLLGVPQG
LLAETGAVSAEVAKAMARGARQLAGSDLALAVTGIAGPEGGSPDKPVGTVFIALADQAGCSAKGYHFRGDRDRIRTITAV
TAMDWLRRRLLSH
>Mature_413_residues
MKTALLSIGDELLLGEVVDTNSARIAARLADEGIVTARKLTVGDDEGEIAGALEELARGHDVVIATGGLGPTDDDVTARA
AARATGRRLVLNEEAMGHLREFFVRLGREMHPANGRQCLLPAKAELIPNPTGTASGFYLPLDRCLLMFLPGVPSEMAVML
DETVVPLVLERRGEHRRTRTLTLTVFGLSEAEIGARLSDLDRSRPGLTVAYCVEYPVVQVKLRATGEDEGALTALLEDGA
ALVRERLGGHVVAGDGETIDTTVARLFRETGMTLALAESCTGGLIAGRVTAIPGSSAYFFLSAVTYANDAKARLLGVPQG
LLAETGAVSAEVAKAMARGARQLAGSDLALAVTGIAGPEGGSPDKPVGTVFIALADQAGCSAKGYHFRGDRDRIRTITAV
TAMDWLRRRLLSH

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=290, Percent_Identity=38.2758620689655, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1789052, Length=152, Percent_Identity=44.078947368421, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787818, Length=121, Percent_Identity=38.0165289256198, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71993974, Length=284, Percent_Identity=28.8732394366197, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993966, Length=284, Percent_Identity=28.8732394366197, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323832, Length=170, Percent_Identity=32.9411764705882, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_GEOMG (Q39Z82)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_383167.1
- ProteinModelPortal:   Q39Z82
- STRING:   Q39Z82
- GeneID:   3739658
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_0196
- NMPDR:   fig|269799.3.peg.227
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- PhylomeDB:   Q39Z82
- ProtClustDB:   CLSK827663
- BioCyc:   GMET269799:GMET_0196-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR020817
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 43545; Mature: 43545

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTALLSIGDELLLGEVVDTNSARIAARLADEGIVTARKLTVGDDEGEIAGALEELARGH
CCCEEECCCCHHEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHCCC
DVVIATGGLGPTDDDVTARAAARATGRRLVLNEEAMGHLREFFVRLGREMHPANGRQCLL
EEEEEECCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCEEEE
PAKAELIPNPTGTASGFYLPLDRCLLMFLPGVPSEMAVMLDETVVPLVLERRGEHRRTRT
CCHHHHCCCCCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
LTLTVFGLSEAEIGARLSDLDRSRPGLTVAYCVEYPVVQVKLRATGEDEGALTALLEDGA
EEEEEEECCHHHHCCHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHCCH
ALVRERLGGHVVAGDGETIDTTVARLFRETGMTLALAESCTGGLIAGRVTAIPGSSAYFF
HHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEECEEEECCCCCEEEE
LSAVTYANDAKARLLGVPQGLLAETGAVSAEVAKAMARGARQLAGSDLALAVTGIAGPEG
EEEEHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GSPDKPVGTVFIALADQAGCSAKGYHFRGDRDRIRTITAVTAMDWLRRRLLSH
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTALLSIGDELLLGEVVDTNSARIAARLADEGIVTARKLTVGDDEGEIAGALEELARGH
CCCEEECCCCHHEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHCCC
DVVIATGGLGPTDDDVTARAAARATGRRLVLNEEAMGHLREFFVRLGREMHPANGRQCLL
EEEEEECCCCCCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCEEEE
PAKAELIPNPTGTASGFYLPLDRCLLMFLPGVPSEMAVMLDETVVPLVLERRGEHRRTRT
CCHHHHCCCCCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
LTLTVFGLSEAEIGARLSDLDRSRPGLTVAYCVEYPVVQVKLRATGEDEGALTALLEDGA
EEEEEEECCHHHHCCHHHHHHCCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHCCH
ALVRERLGGHVVAGDGETIDTTVARLFRETGMTLALAESCTGGLIAGRVTAIPGSSAYFF
HHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEECEEEECCCCCEEEE
LSAVTYANDAKARLLGVPQGLLAETGAVSAEVAKAMARGARQLAGSDLALAVTGIAGPEG
EEEEHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GSPDKPVGTVFIALADQAGCSAKGYHFRGDRDRIRTITAVTAMDWLRRRLLSH
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA