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The map label for this gene is pgpA [H]

Identifier: 78221419

GI number: 78221419

Start: 225734

End: 226183

Strand: Direct

Name: pgpA [H]

Synonym: Gmet_0195

Alternate gene names: 78221419

Gene position: 225734-226183 (Clockwise)

Preceding gene: 78221418

Following gene: 78221420

Centisome position: 5.65

GC content: 63.33

Gene sequence:

>450_bases
ATGAGGGGCTTCGTCGTCTGCGCGGCAAGCTGGTTCGGTACCGGGTTTTTCCCCGTGGCTTCGGGGACCGTGGGGACCCT
GGGGGCCATCCCCCTCTACCTGGTCCTGGCGCGGCTTCCCCTCTGGCTCTACCTCCTGACTCTCGTCCCCTTCTTCTTCC
TCGCTTCATGGGTCTCAGGGGCGGCGGAACGGGAGTTCGGCGAGAAGGACTCGGGAAAGATCGTCATTGACGAGGTGATC
GGCTTCCTCATAACCATGGCCGGGGCGCCGGTCCACTGGCGGAGCATCGTGATCGGCTTTCTCCTCTTCCGGTTCTTCGA
CATCGTCAAGGTGCCGCCGGCCCGCTACTTCGACCGGCAGGTGAAAAACGGTTACGGCGTGGTCCTCGATGACGTGGTGG
CCGGCATCTACGCCTGCGTGGTGCTCCACGTGATCCTGAGGTTTCTGTGA

Upstream 100 bases:

>100_bases
GGGTAACCCCCGAATACGATGCGTGCCGCCGGATCGCCGCCGAGCGGGAAATGTCGCTTCTGGAGGTCTACCGGATCGTG
GAGCGGGAGGCGGGGGAGCC

Downstream 100 bases:

>100_bases
AAACGGCGCTTCTCTCCATCGGCGACGAACTCCTCCTTGGTGAGGTTGTGGATACCAACTCGGCTCGAATCGCAGCACGG
CTGGCCGACGAGGGGATCGT

Product: phosphatidylglycerophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRGFVVCAASWFGTGFFPVASGTVGTLGAIPLYLVLARLPLWLYLLTLVPFFFLASWVSGAAEREFGEKDSGKIVIDEVI
GFLITMAGAPVHWRSIVIGFLLFRFFDIVKVPPARYFDRQVKNGYGVVLDDVVAGIYACVVLHVILRFL

Sequences:

>Translated_149_residues
MRGFVVCAASWFGTGFFPVASGTVGTLGAIPLYLVLARLPLWLYLLTLVPFFFLASWVSGAAEREFGEKDSGKIVIDEVI
GFLITMAGAPVHWRSIVIGFLLFRFFDIVKVPPARYFDRQVKNGYGVVLDDVVAGIYACVVLHVILRFL
>Mature_149_residues
MRGFVVCAASWFGTGFFPVASGTVGTLGAIPLYLVLARLPLWLYLLTLVPFFFLASWVSGAAEREFGEKDSGKIVIDEVI
GFLITMAGAPVHWRSIVIGFLLFRFFDIVKVPPARYFDRQVKNGYGVVLDDVVAGIYACVVLHVILRFL

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=135, Percent_Identity=37.037037037037, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 16479; Mature: 16479

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFVVCAASWFGTGFFPVASGTVGTLGAIPLYLVLARLPLWLYLLTLVPFFFLASWVSG
CCCEEEEHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEREFGEKDSGKIVIDEVIGFLITMAGAPVHWRSIVIGFLLFRFFDIVKVPPARYFDRQ
HHHHHCCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VKNGYGVVLDDVVAGIYACVVLHVILRFL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRGFVVCAASWFGTGFFPVASGTVGTLGAIPLYLVLARLPLWLYLLTLVPFFFLASWVSG
CCCEEEEHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEREFGEKDSGKIVIDEVIGFLITMAGAPVHWRSIVIGFLLFRFFDIVKVPPARYFDRQ
HHHHHCCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VKNGYGVVLDDVVAGIYACVVLHVILRFL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]