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The map label for this gene is prmA [H]

Identifier: 78221363

GI number: 78221363

Start: 165102

End: 165746

Strand: Direct

Name: prmA [H]

Synonym: Gmet_0136

Alternate gene names: 78221363

Gene position: 165102-165746 (Clockwise)

Preceding gene: 78221359

Following gene: 78221364

Centisome position: 4.13

GC content: 65.12

Gene sequence:

>645_bases
ATGTACGGACGCATCTTCACCCCCTTTGCCATCGGGGGGTTCACCATCGTGCCGGAGGATCATCCCGAGGACCCGGCAGC
GGGCCTCCCCCTCATCATGGGGAAAAAAGGGGCCTTCGGCTCCGGCGAGCACGAGACCACCGCCTCCTGCCTGGAAGAGA
TGGAGCGAATCCCCGGCATCGCCGGCATGCGCTGCCTCGATCTCGGGAGCGGCACCGGCATCCTGGCCGTGGCCGCCATC
CGCCTCGGAGCCGCCAGCGTGGTGGCGGTGGACATCGACCCAAAGGCCGCTGAATCGTGCGCCGCCAACGTGCGCCTCAA
CGGCATGGAGGGACGGATCTTCTCCGTCTGCGGCGAACTGGCCTCGGTGGGGCGGGAACCCTACGACCTCCTCCTGGCCA
ACATCTACGCCGACATCCACCTGGCCCTGGCCCACGAGATGGTGGGGCTCGTGCGCCCCGGCGGGTGGCTCATCCTCTCC
GGCATTCCGCTTCAGGACAAGTTCGACATCCAGCGCCGCTTCCGGAACCTGGGATGCATCGAGCACGACTGGCAAATCCT
GGAGGAATACGTCACCATCGTCCTGCGCAAGCCTGACGCGGAAGGCGATGAAATGATTGACGAGAAGGCTGCATCCTCAT
TATAA

Upstream 100 bases:

>100_bases
CCGCACTATCGCCCGTCAAGTCAACCTTTTGTTTATTTCTTTCACCGTCGAATTGGGGTATGGTTTTCCCTTCACCACGC
CACCGAGGAGGCCCATGCCT

Downstream 100 bases:

>100_bases
TTCAGCGGTTTGATTATCGACTCGGAGGAGTGACACTATGTTCAAACGGATTATCCTGGCCCTGACAATCTGCGGTCTTT
TCAGCGTGCTTCTCATCGCC

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MYGRIFTPFAIGGFTIVPEDHPEDPAAGLPLIMGKKGAFGSGEHETTASCLEEMERIPGIAGMRCLDLGSGTGILAVAAI
RLGAASVVAVDIDPKAAESCAANVRLNGMEGRIFSVCGELASVGREPYDLLLANIYADIHLALAHEMVGLVRPGGWLILS
GIPLQDKFDIQRRFRNLGCIEHDWQILEEYVTIVLRKPDAEGDEMIDEKAASSL

Sequences:

>Translated_214_residues
MYGRIFTPFAIGGFTIVPEDHPEDPAAGLPLIMGKKGAFGSGEHETTASCLEEMERIPGIAGMRCLDLGSGTGILAVAAI
RLGAASVVAVDIDPKAAESCAANVRLNGMEGRIFSVCGELASVGREPYDLLLANIYADIHLALAHEMVGLVRPGGWLILS
GIPLQDKFDIQRRFRNLGCIEHDWQILEEYVTIVLRKPDAEGDEMIDEKAASSL
>Mature_214_residues
MYGRIFTPFAIGGFTIVPEDHPEDPAAGLPLIMGKKGAFGSGEHETTASCLEEMERIPGIAGMRCLDLGSGTGILAVAAI
RLGAASVVAVDIDPKAAESCAANVRLNGMEGRIFSVCGELASVGREPYDLLLANIYADIHLALAHEMVGLVRPGGWLILS
GIPLQDKFDIQRRFRNLGCIEHDWQILEEYVTIVLRKPDAEGDEMIDEKAASSL

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22948; Mature: 22948

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGRIFTPFAIGGFTIVPEDHPEDPAAGLPLIMGKKGAFGSGEHETTASCLEEMERIPGI
CCCCEECCEEECCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
AGMRCLDLGSGTGILAVAAIRLGAASVVAVDIDPKAAESCAANVRLNGMEGRIFSVCGEL
CCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCEEECCCCCHHHHHHHHH
ASVGREPYDLLLANIYADIHLALAHEMVGLVRPGGWLILSGIPLQDKFDIQRRFRNLGCI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
EHDWQILEEYVTIVLRKPDAEGDEMIDEKAASSL
HHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MYGRIFTPFAIGGFTIVPEDHPEDPAAGLPLIMGKKGAFGSGEHETTASCLEEMERIPGI
CCCCEECCEEECCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
AGMRCLDLGSGTGILAVAAIRLGAASVVAVDIDPKAAESCAANVRLNGMEGRIFSVCGEL
CCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCEEECCCCCHHHHHHHHH
ASVGREPYDLLLANIYADIHLALAHEMVGLVRPGGWLILSGIPLQDKFDIQRRFRNLGCI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
EHDWQILEEYVTIVLRKPDAEGDEMIDEKAASSL
HHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA